Controlled capture and release of cardiac fibroblasts using peptide-functionalized alginate gels in microfluidic channels

Lab on a Chip ◽  
2009 ◽  
Vol 9 (11) ◽  
pp. 1507 ◽  
Author(s):  
Brian D. Plouffe ◽  
Melissa A. Brown ◽  
Rohin K. Iyer ◽  
Milica Radisic ◽  
Shashi K. Murthy
Keyword(s):  
Cardiac Fibroblasts ◽  
Microfluidic Channels ◽  
Capture And Release ◽  
Alginate Gels

Light-Directed Self-Assembly of Robust Alginate Gels at Precise Locations in Microfluidic Channels

2016 ◽  
Vol 8 (27) ◽  
pp. 17529-17538 ◽  
Author(s):  
Hyuntaek Oh ◽  
Annie Xi Lu ◽  
Vishal Javvaji ◽  
Don L. DeVoe ◽  
Srinivasa R. Raghavan
Keyword(s):  
Self Assembly ◽  
Microfluidic Channels ◽  
Alginate Gels

Protective role of peroxiredoxin-4 in heart failure

2020 ◽  
Vol 134 (1) ◽  
pp. 71-72
Author(s):  
Naseer Ahmed ◽  
Masooma Naseem ◽  
Javeria Farooq
Keyword(s):  
Heart Failure ◽  
Cardiac Fibroblasts ◽  
Protective Role ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Galectin 3 ◽  
Consequent Increase ◽  
And Oxidative Stress

Abstract Recently, we have read with great interest the article published by Ibarrola et al. (Clin. Sci. (Lond.) (2018) 132, 1471–1485), which used proteomics and immunodetection methods to show that Galectin-3 (Gal-3) down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers in cardiac fibroblasts.’ We would like to point out some results stated in the article that need further investigation and more detailed discussion to clarify certain factors involved in the protective role of Prx-4 in heart failure.

Grafting of Connexin43 (Cx43) Overexpressing Cardiac Fibroblasts Protects from Postinfarct Arrhythmia

2020 ◽  
Author(s):  
M. Schiffer ◽  
E. Carls ◽  
G. D. Dürr ◽  
H. Treede ◽  
J. M. Delafuente ◽  
...  
Keyword(s):  
Cardiac Fibroblasts

JOULE HEATING INDUCED HEAT TRANSFER IN ELECTROKINETIC FLOW THROUGH MICROFLUIDIC CHANNELS

Equipment ◽  
2006 ◽  
Author(s):  
C. Yang ◽  
G. Y. Tang ◽  
D. G. Yan ◽  
H. Q. Gong ◽  
John C. Chai ◽  
...  
Keyword(s):  
Heat Transfer ◽  
Joule Heating ◽  
Microfluidic Channels ◽  
Electrokinetic Flow ◽  
Flow Through

Stochastic Computing via In Operando Modulation of Rectification in Molecular Tunneling Junctions

2020 ◽  
Author(s):  
Xinkai Qiu ◽  
Sylvia Rousseva ◽  
Gang Ye ◽  
Jan C. Hummelen ◽  
Ryan Chiechi
Keyword(s):  
Self Assembly ◽  
Variable Temperature ◽  
Self Assembled Monolayers ◽  
Microfluidic Channels ◽  
Proof Of Concept ◽  
Glycol Ethers ◽  
Stochastic Computing ◽  
Assembled Monolayers ◽  
In Operando ◽  
Tunneling Junctions

This paper describes the reconfiguration of molecular tunneling junctions during operation via the self-assembly of bilayers of glycol ethers. We use well-established functional groups to modulate the magnitude and direction of rectification in assembled tunneling junctions by exposing them to solutions containing different glycol ethers. Variable-temperature measurements establish that rectification occurs by a bias-dependent tunneling-hopping mechanism and that glycol ethers, beside being an unusually efficient tunneling medium, behave identically to alkanes. We fabricated memory bits from crossbar junctions prepared by injecting eutectic Ga-In into microfluidic channels. Two 8-bit registers were able to perform logical AND operations on bit strings encoded into chemical packets as microfluidic droplets that alter the composition of the crossbar junctions through self-assembly to effect memristor-like properties. This proof of concept work demonstrates the potential for fieldable molecular-electronic devices based on tunneling junctions of self-assembled monolayers and bilayers.

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