Gold and platinum catalysis—a convenient tool for generating molecular complexity

2009 ◽  
Vol 38 (11) ◽  
pp. 3208 ◽  
Author(s):  
Alois Fürstner
Keyword(s):  
Convenient Tool ◽  
Platinum Catalysis ◽  
Molecular Complexity

Can Crowdfunding Come to the Rescue of Culture and Arts? Evidence from Romania

2019 ◽  
Vol 3 (2) ◽  
pp. 73-82
Author(s):  
Mina Fanea-Ivanovici
Keyword(s):  
Success Rate ◽  
Public Financing ◽  
Artistic Creation ◽  
Cultural Activities ◽  
Convenient Tool ◽  
Cost Disease ◽  
Artistic Activity ◽  
To Receive

Financing culture and arts is a difficult task to achieve, especially due to the fact that the revenues ob-tained from such activities may not be enough to cover the costs. This has been claimed to be true for certain cultural activities or events, such as concerts, and is named Baumol’s cost disease. Although other forms of cultural and artistic activity can entirely rely upon the revenues earned, many types of artistic creation depend on public financing or sponsorship. With the advent and democratisation of Internet-based technologies, crowdfunding has become a convenient tool to raise funds in order to fi-nance cultural activities. The aim of this paper is to investigate to what extent cultural and artistic pro-jects are likely to receive financing through crowdfunding. The study is based on the main Romanian crowdfunding platforms and analyses the success rate of crowdfunding projects in culture and arts.

scholarly journals New bi-harmonic superspace formulation of 4D, $$ \mathcal{N} $$ = 4 SYM theory

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
I. L. Buchbinder ◽  
E. A. Ivanov ◽  
V. A. Ivanovskiy
Keyword(s):  
Effective Action ◽  
Harmonic Superspace ◽  
Four Dimensions ◽  
Yang Mills ◽  
Convenient Tool ◽  
Leading Term

Abstract We develop a novel bi-harmonic $$ \mathcal{N} $$ N = 4 superspace formulation of the $$ \mathcal{N} $$ N = 4 supersymmetric Yang-Mills theory (SYM) in four dimensions. In this approach, the $$ \mathcal{N} $$ N = 4 SYM superfield constraints are solved in terms of on-shell $$ \mathcal{N} $$ N = 2 harmonic superfields. Such an approach provides a convenient tool of constructing the manifestly $$ \mathcal{N} $$ N = 4 supersymmetric invariants and further rewriting them in $$ \mathcal{N} $$ N = 2 harmonic superspace. In particular, we present $$ \mathcal{N} $$ N = 4 superfield form of the leading term in the $$ \mathcal{N} $$ N = 4 SYM effective action which was known previously in $$ \mathcal{N} $$ N = 2 superspace formulation.

scholarly journals Identifying molecules as biosignatures with assembly theory and mass spectrometry

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Stuart M. Marshall ◽  
Cole Mathis ◽  
Emma Carrick ◽  
Graham Keenan ◽  
Geoffrey J. T. Cooper ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
De Novo ◽  
Outer Space ◽  
Molecular Assembly ◽  
Detection Experiment ◽  
Complex Molecules ◽  
The World ◽  
Life Detection ◽  
Molecular Complexity ◽  
The Universe

AbstractThe search for alien life is hard because we do not know what signatures are unique to life. We show why complex molecules found in high abundance are universal biosignatures and demonstrate the first intrinsic experimentally tractable measure of molecular complexity, called the molecular assembly index (MA). To do this we calculate the complexity of several million molecules and validate that their complexity can be experimentally determined by mass spectrometry. This approach allows us to identify molecular biosignatures from a set of diverse samples from around the world, outer space, and the laboratory, demonstrating it is possible to build a life detection experiment based on MA that could be deployed to extraterrestrial locations, and used as a complexity scale to quantify constraints needed to direct prebiotically plausible processes in the laboratory. Such an approach is vital for finding life elsewhere in the universe or creating de-novo life in the lab.

scholarly journals Genetic and Transcriptomic Biomarkers in Neurodegenerative Diseases: Current Situation and the Road Ahead

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1030
Author(s):  
Julie Lake ◽  
Catherine S. Storm ◽  
Mary B. Makarious ◽  
Sara Bandres-Ciga
Keyword(s):  
Neurodegenerative Diseases ◽  
Large Scale ◽  
Disease Diagnosis ◽  
Open Science ◽  
Future Directions ◽  
The Road ◽  
Current State ◽  
Molecular Complexity ◽  
Science Framework ◽  
Lateral Sclerosis

Neurodegenerative diseases are etiologically and clinically heterogeneous conditions, often reflecting a spectrum of disease rather than well-defined disorders. The underlying molecular complexity of these diseases has made the discovery and validation of useful biomarkers challenging. The search of characteristic genetic and transcriptomic indicators for preclinical disease diagnosis, prognosis, or subtyping is an area of ongoing effort and interest. The next generation of biomarker studies holds promise by implementing meaningful longitudinal and multi-modal approaches in large scale biobank and healthcare system scale datasets. This work will only be possible in an open science framework. This review summarizes the current state of genetic and transcriptomic biomarkers in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis, providing a comprehensive landscape of recent literature and future directions.

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