Molecular dynamics study of zinc binding to cysteines in a peptide mimic of the alcohol dehydrogenase structural zinc site

Erik G. Brandt; Mikko Hellgren; Tore Brinck; Tomas Bergman; Olle Edholm

doi:10.1039/b815482a

Molecular dynamics study of zinc binding to cysteines in a peptide mimic of the alcohol dehydrogenase structural zinc site

Physical Chemistry Chemical Physics ◽

10.1039/b815482a ◽

2009 ◽

Vol 11 (6) ◽

pp. 975-983 ◽

Cited By ~ 37

Author(s):

Erik G. Brandt ◽

Mikko Hellgren ◽

Tore Brinck ◽

Tomas Bergman ◽

Olle Edholm

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Zinc Binding ◽

Peptide Mimic ◽

Zinc Site

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Zinc binding to peptide analogs of the structural zinc site in alcohol dehydrogenase: Implications for an entatic state

Cellular and Molecular Life Sciences ◽

10.1007/s00018-008-8379-5 ◽

2008 ◽

Vol 65 (24) ◽

pp. 4019-4027 ◽

Cited By ~ 12

Author(s):

T. Bergman ◽

K. Zhang ◽

C. Palmberg ◽

H. Jörnvall ◽

D. S. Auld

Keyword(s):

Alcohol Dehydrogenase ◽

Zinc Binding ◽

Entatic State ◽

Peptide Analogs ◽

Zinc Site

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Zinc Binding Characteristics of the Synthetic Peptide Corresponding to the Structural Zinc Site of Horse Liver Alcohol Dehydrogenase

Advances in Experimental Medicine and Biology - Enzymology and Molecular Biology of Carbonyl Metabolism 7 ◽

10.1007/978-1-4615-4735-8_41 ◽

1999 ◽

pp. 339-342

Author(s):

Tomas Bergman ◽

Carina Palmberg ◽

Hans Jörnvall ◽

David S. Auld ◽

Bert L. Vallée

Keyword(s):

Alcohol Dehydrogenase ◽

Synthetic Peptide ◽

Zinc Binding ◽

Horse Liver Alcohol Dehydrogenase ◽

Binding Characteristics ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Zinc Site

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Molecular Dynamics Simulation Studies on Effects of Erythritol on Alcohol Dehydrogenase Folding~!2010-03-01~!2010-06-08~!2010-07-20~!

The Open Nutraceuticals Journal ◽

10.2174/1876396001003010213 ◽

2010 ◽

Vol 3 (1) ◽

pp. 213-219

Author(s):

Surya Dwivedi

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Alcohol Dehydrogenase ◽

Dynamics Simulation ◽

Simulation Studies

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Synthetic model peptides of the noncatalytic zinc site of EE and SS isozymes of horse liver alcohol dehydrogenase: Interaction with cobalt (II) and nickel (II) ions

Journal of Inorganic Biochemistry ◽

10.1016/0162-0134(95)97417-o ◽

1995 ◽

Vol 59 (2-3) ◽

pp. 316

Author(s):

Grazyna Formicka ◽

Ralf Hoffmann ◽

Stephan Rawer ◽

Michael Zeppezauer

Keyword(s):

Alcohol Dehydrogenase ◽

Horse Liver Alcohol Dehydrogenase ◽

Synthetic Model ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Zinc Site ◽

Model Peptides

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Coordination geometry for cadmium in the catalytic zinc site of horse liver alcohol dehydrogenase: studies by PAC spectroscopy

European Biophysics Journal ◽

10.1007/bf00183458 ◽

1991 ◽

Vol 20 (4) ◽

Cited By ~ 16

Author(s):

R. Bauer ◽

H.W. Adolph ◽

I. Andersson ◽

E. Danielsen ◽

G. Formicka ◽

...

Keyword(s):

Alcohol Dehydrogenase ◽

Coordination Geometry ◽

Pac Spectroscopy ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Catalytic Zinc ◽

Zinc Site

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Comparison of the effects of sucrose molecules on alcohol dehydrogenase folding with those of sorbitol molecules on alcohol dehydrogenase folding using molecular dynamics simulation

Journal of the Iranian Chemical Society ◽

10.1007/s13738-015-0671-3 ◽

2015 ◽

Vol 12 (11) ◽

pp. 1973-1982 ◽

Cited By ~ 7

Author(s):

Homayoon Bahrami ◽

Mansour Zahedi

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Alcohol Dehydrogenase ◽

Dynamics Simulation

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Spectroscopic studies of the metal(II) complexes with peptides simulating the noncatalytic zinc-binding site of horse liver alcohol dehydrogenase

Peptides 1992 ◽

10.1007/978-94-011-1470-7_431 ◽

1993 ◽

pp. 940-941

Author(s):

Stefan Rawer ◽

Ralf Hoffmann ◽

Grazyna Formicka ◽

Michael Zeppezauer

Keyword(s):

Alcohol Dehydrogenase ◽

Binding Site ◽

Spectroscopic Studies ◽

Zinc Binding ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Zinc Binding Site

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Review for "Zinc Binding Promotes Greater Hydrophobicity in Alzheimer's Aβ42 peptide than Copper Binding: Molecular Dynamics and Solvation Thermodynamics Studies"

10.1002/prot.25901/v2/review2 ◽

2020 ◽

Keyword(s):

Molecular Dynamics ◽

Zinc Binding ◽

Copper Binding ◽

Solvation Thermodynamics ◽

Aβ42 Peptide

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Review for "Zinc Binding Promotes Greater Hydrophobicity in Alzheimer's Aβ42 peptide than Copper Binding: Molecular Dynamics and Solvation Thermodynamics Studies"

10.1002/prot.25901/v1/review2 ◽

2020 ◽

Keyword(s):

Molecular Dynamics ◽

Zinc Binding ◽

Copper Binding ◽

Solvation Thermodynamics ◽

Aβ42 Peptide

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Response to Comment on “Effect of Active Site Mutation Phe93 → Trp in the Horse Liver Alcohol Dehydrogenase Enzyme on Catalysis: A Molecular Dynamics Study”

The Journal of Physical Chemistry B ◽

10.1021/jp035474+ ◽

2003 ◽

Vol 107 (44) ◽

pp. 12372-12372 ◽

Cited By ~ 2

Author(s):

Steven D. Schwartz

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Active Site ◽

Site Mutation ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Dehydrogenase Enzyme

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