Analyzing effects of photodynamic therapy with 5-aminolevulinic acid (ALA) induced protoporphyrin IX (PPIX) in urothelial cells using reverse phase protein arrays

2007 ◽  
Vol 6 (12) ◽  
pp. 1296 ◽  
Author(s):  
R. C. Krieg ◽  
A. Herr ◽  
K. Raupach ◽  
Q. Ren ◽  
K. Schwamborn ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Aminolevulinic Acid ◽  
Protoporphyrin Ix ◽  
Urothelial Cells ◽  
Reverse Phase ◽  
Protein Arrays ◽  
Phase Protein

Protoporphyrin IX Fluorescence Photobleaching and the Response of Rat Barrett's Esophagus Following 5-aminolevulinic Acid Photodynamic Therapy

2006 ◽  
Vol 82 (6) ◽  
pp. 1638 ◽  
Author(s):  
Ingrid A. Boere ◽  
Dominic J. Robinson ◽  
Henriette S. de Bruijn ◽  
Jolanda Kluin ◽  
Hugo W. Tilanus ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Aminolevulinic Acid ◽  
Protoporphyrin Ix

scholarly journals Systematic Review and Meta-Analysis of In Vitro Anti-Human Cancer Experiments Investigating the Use of 5-Aminolevulinic Acid (5-ALA) for Photodynamic Therapy

2021 ◽  
Vol 14 (3) ◽  
pp. 229
Author(s):  
Yo Shinoda ◽  
Daitetsu Kato ◽  
Ryosuke Ando ◽  
Hikaru Endo ◽  
Tsutomu Takahashi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Photodynamic Therapy ◽  
Aminolevulinic Acid ◽  
Human Cancer ◽  
Meta Analysis ◽  
Protoporphyrin Ix ◽  
Cell Types ◽  
Amino Acid Derivative ◽  
Photodynamic Diagnosis

5-Aminolevulinic acid (5-ALA) is an amino acid derivative and a precursor of protoporphyrin IX (PpIX). The photophysical feature of PpIX is clinically used in photodynamic diagnosis (PDD) and photodynamic therapy (PDT). These clinical applications are potentially based on in vitro cell culture experiments. Thus, conducting a systematic review and meta-analysis of in vitro 5-ALA PDT experiments is meaningful and may provide opportunities to consider future perspectives in this field. We conducted a systematic literature search in PubMed to summarize the in vitro 5-ALA PDT experiments and calculated the effectiveness of 5-ALA PDT for several cancer cell types. In total, 412 articles were identified, and 77 were extracted based on our inclusion criteria. The calculated effectiveness of 5-ALA PDT was statistically analyzed, which revealed a tendency of cancer-classification-dependent sensitivity to 5-ALA PDT, and stomach cancer was significantly more sensitive to 5-ALA PDT compared with cancers of different origins. Based on our analysis, we suggest a standardized in vitro experimental protocol for 5-ALA PDT.

Subtyping of breast cancer using reverse phase protein arrays

2014 ◽  
Vol 11 (6) ◽  
pp. 757-770 ◽  
Author(s):  
Johanna Sonntag ◽  
Kerstin Schlüter ◽  
Stephan Bernhardt ◽  
Ulrike Korf
Keyword(s):  
Breast Cancer ◽  
Reverse Phase ◽  
Protein Arrays ◽  
Phase Protein

scholarly journals eEF1A1 binds and enriches protoporphyrin IX in cancer cells in 5-aminolevulinic acid based photodynamic therapy

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Zhichao Fan ◽  
Xiaojun Cui ◽  
Dan Wei ◽  
Wei Liu ◽  
Buhong Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Aminolevulinic Acid ◽  
Protoporphyrin Ix

Characterization of Kinase Inhibitors Using Reverse Phase Protein Arrays

2011 ◽  
pp. 79-107 ◽  
Author(s):  
Georg Martiny-Baron ◽  
Dorothea Haasen ◽  
Daniel D’Dorazio ◽  
Johannes Voshol ◽  
Doriano Fabbro
Keyword(s):  
Kinase Inhibitors ◽  
Reverse Phase ◽  
Protein Arrays ◽  
Phase Protein

Characterization of Signalling Pathways by Reverse Phase Protein Arrays

2013 ◽  
pp. 285-299 ◽  
Author(s):  
Katharina Malinowsky ◽  
Claudia Wolff ◽  
Christina Schott ◽  
Karl-Friedrich Becker
Keyword(s):  
Signalling Pathways ◽  
Reverse Phase ◽  
Protein Arrays ◽  
Phase Protein

Protein Arrays III: Reverse-Phase Protein Arrays

2017 ◽  
pp. 279-289 ◽  
Author(s):  
Yulin Yuan ◽  
Xia Hong ◽  
Zuan-Tao Lin ◽  
Hongting Wang ◽  
Mikala Heon ◽  
...  
Keyword(s):  
Reverse Phase ◽  
Protein Arrays ◽  
Phase Protein
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