An astrophysically-relevant mechanism for amino acid enantiomer enrichment

2007 ◽  
pp. 2578 ◽  
Author(s):  
Stephen P. Fletcher ◽  
Richard B. C. Jagt ◽  
Ben L. Feringa
Keyword(s):  
Amino Acid ◽  
Enantiomer Enrichment ◽  
Amino Acid Enantiomer

Aqueous-phase quantitative NMR determination of amino acid enantiomer ratio by 13C-NMR using chiral neodymium shift reagent

Amino Acids ◽  
2009 ◽  
Vol 38 (5) ◽  
pp. 1343-1350 ◽  
Author(s):  
Nicola Florini ◽  
Francesco Faglioni ◽  
Claudia Zucchi ◽  
Luciano Caglioti ◽  
Gyula Pályi
Keyword(s):  
Amino Acid ◽  
Aqueous Phase ◽  
13C Nmr ◽  
Shift Reagent ◽  
Quantitative Nmr ◽  
Amino Acid Enantiomer

Dansyl amino acid enantiomer separation on a teicoplanin chiral stationary phase: effect of eluent pH

2001 ◽  
Vol 923 (1-2) ◽  
pp. 37-43 ◽  
Author(s):  
Eric Peyrin ◽  
Corinne Ravelet ◽  
Edwige Nicolle ◽  
Annick Villet ◽  
Catherine Grosset ◽  
...  
Keyword(s):  
Amino Acid ◽  
Stationary Phase ◽  
Chiral Stationary Phase ◽  
Enantiomer Separation ◽  
Phase Effect ◽  
Dansyl Amino Acid ◽  
Amino Acid Enantiomer

Separation of amino acid enantiomers by a capillary modified with a metal–organic framework

RSC Advances ◽  
2016 ◽  
Vol 6 (47) ◽  
pp. 41587-41593 ◽  
Author(s):  
Nengsheng Ye ◽  
Jichao Ma ◽  
Jianxin An ◽  
Jian Li ◽  
Zhimin Cai ◽  
...  
Keyword(s):  
Amino Acid ◽  
Capillary Electrochromatography ◽  
Enantiomer Separation ◽  
Metal Organic Framework ◽  
Covalent Bonding ◽  
Amino Acid Enantiomers ◽  
Metal Organic ◽  
Amino Acid Enantiomer ◽  
Organic Framework

Covalent bonding of homochiral metal–organic framework in capillaries for amino acid enantiomer separation by capillary electrochromatography.

scholarly journals Broad-Spectrum Antimicrobial Activity and Improved Stability of a D-Amino Acid Enantiomer of DMPC-10A, the Designed Derivative of Dermaseptin Truncates

Antibiotics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 627
Author(s):  
Yu Zai ◽  
Yuan Ying ◽  
Zhuming Ye ◽  
Mei Zhou ◽  
Chengbang Ma ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Amino Acid ◽  
Broad Spectrum ◽  
Hemolytic Activity ◽  
Galleria Mellonella ◽  
Amino Acid Residues ◽  
Antibiotic Resistant ◽  
Promising Alternative ◽  
Improved Stability ◽  
Amino Acid Enantiomer

DMPC-10A (ALWKKLLKK-Cha-NH2) is a 10-mer peptide derivative from the N-terminal domain of Dermaseptin-PC which has shown broad-spectrum antimicrobial activity as well as a considerable hemolytic effect. In order to reduce hemolytic activity and improve stability to endogenous enzymes, a D-amino acid enantiomer (DMPC-10B) was designed by substituting all L-Lys and L-Leu with their respective D-form amino acid residues, while the Ala1 and Trp3 remained unchanged. The D-amino acid enantiomer exhibited similar antimicrobial potency to the parent peptide but exerted lower cytotoxicity and hemolytic activity. Meanwhile, DMPC-10B exhibited remarkable resistance to hydrolysis by trypsin and chymotrypsin. In addition to these advantages, DMPC-10B exhibited an outstanding antibacterial effect against Methicillin-resistant Staphylococcus aureus (MRSA) and Klebsiella pneumoniae using the Galleria mellonella larva model and displayed synergistic activities with gentamicin against carbapenem-resistant K. pneumoniae strains. This indicates that DMPC-10B would be a promising alternative for treating antibiotic-resistant pathogens.

scholarly journals Enzyme-Based Microfluidic Chip Coupled to Graphene Electrodes for the Detection of D-Amino Acid Enantiomer-Biomarkers

2015 ◽  
Vol 87 (10) ◽  
pp. 5074-5078 ◽  
Author(s):  
Pilar Batalla ◽  
Aída Martín ◽  
Miguel Ángel López ◽  
María Cristina González ◽  
Alberto Escarpa
Keyword(s):  
Amino Acid ◽  
Microfluidic Chip ◽  
Amino Acid Enantiomer

Amino acid enantiomer separation for the detection of adulteration in fruit juices

1984 ◽  
Vol 7 (5) ◽  
pp. 284-285 ◽  
Author(s):  
W. Ooghe ◽  
H. Kasteleyn ◽  
I. Temmerman ◽  
P. Sandra
Keyword(s):  
Amino Acid ◽  
Enantiomer Separation ◽  
Fruit Juices ◽  
Amino Acid Enantiomer

scholarly journals The nonconservative distribution pattern of organic matter in the Rajang, a tropical river with peatland in its estuary

2020 ◽  
Vol 17 (9) ◽  
pp. 2473-2485
Author(s):  
Zhuo-Yi Zhu ◽  
Joanne Oakes ◽  
Bradley Eyre ◽  
Youyou Hao ◽  
Edwin Sien Aun Sia ◽  
...  
Keyword(s):  
Organic Matter ◽  
Amino Acid ◽  
Organic Carbon ◽  
Dissolved Organic Matter ◽  
Anthropogenic Activities ◽  
Field Investigation ◽  
Carbon And Nitrogen ◽  
Organic Matter Composition ◽  
Doc Concentration ◽  
Amino Acid Enantiomer

Abstract. Southeast Asian peatland-draining rivers have attracted much attention due to their high dissolved organic carbon (DOC) yield and high CO2 emissions under anthropogenic influences. In August 2016, we carried out a field investigation of the Rajang River and its estuary, a tropical system located in Sarawak, Malaysia. The Rajang has peatland in its estuary, while the river basin is covered by tropical rainforest. DOC-δ13C in the Rajang ranged from −28.7 ‰ to −20.1 ‰, with a U-shaped trend from river to estuary. For particulate organic carbon (POC), δ13C ranged between −29.4 ‰ and −31.1 ‰ in the river, and there was a clear increasing trend towards more enriched δ13C values with higher salinity. In the estuary, there was a linear conservative dilution pattern for dissolved organic matter composition (as quantified by D- and L-amino acid enantiomers) plotted against DOC-δ13C, whereas when plotted against salinity, dissolved D- and L-amino acid enantiomer values were higher than the theoretical dilution value. Together, these data indicate that the addition of DOC to the estuary (by peatland) not only increased the DOC concentration but also altered its composition, by adding more biodegraded, 13C-depleted organic matter into the bulk dissolved organic matter. Alteration of organic matter composition (addition of a more degraded subpart) was also apparent for the particulate phase, but patterns were less clear. The Rajang was characterized by DOC to DON (dissolved organic nitrogen) ratios of 50 in the river section, with loss of DON in the estuary increasing the ratio to 140, suggesting an unbalanced export of organic carbon and nitrogen. Where affected by anthropogenic activities, further assessment of organic carbon to nitrogen ratios is needed.

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