Induction of cell death by photodynamic therapy with water-soluble lipid-membrane-incorporated [60]fullerene

2007 ◽  
Vol 5 (8) ◽  
pp. 1158 ◽  
Author(s):  
Atsushi Ikeda ◽  
Yuki Doi ◽  
Koji Nishiguchi ◽  
Keiko Kitamura ◽  
Mineo Hashizume ◽  
...  
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Lipid Membrane ◽  
Water Soluble

Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

2017 ◽  
Author(s):  
Ellen Sletten ◽  
Rachael A. Day ◽  
Daniel A. Estabrook ◽  
Jessica K. Logan
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Induce Cell Death ◽  
Perfluorocarbon Nanoemulsions

<p>Photodynamic therapy (PDT) requires photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT. </p>

Combination of photodynamic therapy with doxorubicin in osteosarcoma: Cell death and the role of oxidative stress

2016 ◽  
Vol 61 ◽  
pp. S141
Author(s):  
B. Serambeque ◽  
G. Brites ◽  
M. Laranjo ◽  
G. Chohfi de Miguel ◽  
A. Serra ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Death ◽  
Photodynamic Therapy ◽  
Osteosarcoma Cell

Photodynamic Therapy with Liposomal Zinc Phthalocyanine and Tirapazamine Increases Tumor Cell Death via DNA Damage

2017 ◽  
Vol 13 (2) ◽  
pp. 204-220 ◽  
Author(s):  
Mans Broekgaarden ◽  
Ruud Weijer ◽  
AlbertC. van Wijk ◽  
RuudC. Cox ◽  
MaartenR. Egmond ◽  
...  
Keyword(s):  
Dna Damage ◽  
Cell Death ◽  
Photodynamic Therapy ◽  
Tumor Cell ◽  
Zinc Phthalocyanine ◽  
Tumor Cell Death

scholarly journals Protection by Bcl-2 against apoptotic but not autophagic cell death after photodynamic therapy

Autophagy ◽  
2008 ◽  
Vol 4 (1) ◽  
pp. 125-127 ◽  
Author(s):  
Liang-yan Xue ◽  
Song-mao Chiu ◽  
Kashif Azizuddin ◽  
Sheeba Joseph ◽  
Nancy L. Oleinick
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Autophagic Cell Death

Methylene blue and photodynamic therapy for melanomas: Inducing different rates of cell death (necrosis and apoptosis) in B16-F10 melanoma cells according to methylene blue concentration and energy dose

2021 ◽  
pp. 102635
Author(s):  
Murilo Penteado Del Grande ◽  
Andréa Midory Miyake ◽  
Márcia Kazumi Nagamine ◽  
João Vitor Pereira Leite ◽  
Ivone Izabel Mackowiak da Fonseca ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Cell Death ◽  
Photodynamic Therapy ◽  
Melanoma Cells ◽  
Energy Dose

Simple nanophotosensitizer fabrication using water-soluble chitosan for photodynamic therapy in gastrointestinal cancer cells

2017 ◽  
Vol 532 (1) ◽  
pp. 194-203 ◽  
Author(s):  
Young-IL Jeong ◽  
Byungyoul Cha ◽  
Hye Lim Lee ◽  
Yeon Hui Song ◽  
Yun Hye Jung ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Gastrointestinal Cancer ◽  
Water Soluble

Water-soluble dendritic polyaspartic porphyrins: potential photosensitizers for photodynamic therapy

2012 ◽  
Vol 36 (1) ◽  
pp. 28-31 ◽  
Author(s):  
Baoxiang Gao ◽  
Yueling Liu ◽  
Huijuan Yin ◽  
Yingxin Li ◽  
Qianqian Bai ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Water Soluble

scholarly journals TB-4 Antitumor effects of a novel curcumin derivative curcumin monoglucuronide on glioblastoma cells in vitro and in vivo

2021 ◽  
Vol 3 (Supplement_6) ◽  
pp. vi6-vi6
Author(s):  
Takashi Fujii ◽  
Shun Yamamuro ◽  
Masamichi Takahashi ◽  
Akihide Kondo ◽  
Yoshitaka Narita ◽  
...  
Keyword(s):  
Cell Death ◽  
Water Soluble ◽  
Dependent Manner ◽  
Antitumor Effects ◽  
Multiple Cell ◽  
Human Gbm ◽  
Dose Dependent ◽  
Novel Therapeutic

Abstract The therapeutic outcome of glioblastomas (GBMs) is still very poor. Therefore, invention of novel therapeutic methods against GBM cases is considered urgent. The antitumor effects of naturally-derived compounds are attracting attention recently, and therapeutic efficacy of curcumin, a plant-derived compound previously used for multiple purpose, has been indicated in many cancer systems; however, clinical application of curcumin is considered difficult because of its poor bioavailability (under 1 %). Curcumin monoglucuronide (CMG), a water-soluble prodrug of curcumin recently developed for overcoming this weakness, has been demonstrated excellent antitumor effects for several malignancies in vitro and in vivo; therefore, we investigated the effects of CMG against GBM cells. CMG induced cell death of human GBM cells lines (T98G, U251MG, and U87MG) by dose dependent manner by triggering multiple forms of cell death such as apoptosis and perthanatos. Immunoblotting of CMG-treated GBM cell lysates demonstrated activation of multiple cell death signaling. Furthermore, immunodeficiency mice harboring intracerebral U87MG cell xenografts systemically treated by CMG showed significantly prolonged survival compared with control mice. These results suggest CMG would be a novel therapeutic agent against GBM cases.

Sign in / Sign up

Export Citation Format

Share Document