Correlation of the β-sheet crystal size in silk fibers with the protein amino acid sequence

Soft Matter ◽  
2007 ◽  
Vol 3 (7) ◽  
pp. 877-882 ◽  
Author(s):  
Lawrence F. Drummy ◽  
B. L. Farmer ◽  
Rajesh R. Naik
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Crystal Size ◽  
Protein Amino Acid ◽  
Silk Fibers ◽  
Protein Amino Acid Sequence ◽  
Β Sheet

Shark Myelin Basic Protein: Amino Acid Sequence, Secondary Structure, and Self-Association

1990 ◽  
Vol 55 (3) ◽  
pp. 950-955 ◽  
Author(s):  
Trudy J. Milne ◽  
Annette R. Atkins ◽  
Juanita A. Warren ◽  
Wendy P. Auton ◽  
Ross Smith
Keyword(s):  
Amino Acid ◽  
Secondary Structure ◽  
Amino Acid Sequence ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Protein Amino Acid ◽  
Protein Amino Acid Sequence ◽  
Self Association

scholarly journals Scrapie Resistance in ARQ Sheep

2007 ◽  
Vol 82 (20) ◽  
pp. 10318-10320 ◽  
Author(s):  
W. W. Laegreid ◽  
M. L. Clawson ◽  
M. P. Heaton ◽  
B. T. Green ◽  
K. I. O'Rourke ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Amino Acid ◽  
Amino Acid Sequence ◽  
Survival Time ◽  
Odds Ratio ◽  
Nucleotide Polymorphism ◽  
Protein Amino Acid ◽  
Single Nucleotide ◽  
Prion Gene ◽  
Protein Amino Acid Sequence

ABSTRACT Variation in the ovine prion protein amino acid sequence influences scrapie progression, with sheep homozygous for A136R154Q171 considered susceptible. This study examined the association of survival time of scrapie-exposed ARQ sheep with variation elsewhere in the ovine prion gene. Four single nucleotide polymorphism alleles were associated with prolonged survival. One nonsynonymous allele (T112) was associated with an additional 687 days of survival for scrapie-exposed sheep compared to M112 sheep (odds ratio, 42.5; P = 0.00014). The only two sheep homozygous for T112 (TARQ) did not develop scrapie, suggesting that the allelic effect may be additive. These results provide evidence that TARQ sheep are genetically resistant to development of classical scrapie.

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