A highly efficient and general method for the ring-opening of aziridines with various nucleophiles in DMSO

2006 ◽  
Vol 4 (22) ◽  
pp. 4231 ◽  
Author(s):  
Jie Wu ◽  
Xiaoyu Sun ◽  
Wei Sun
Keyword(s):  
Ring Opening ◽  
Highly Efficient ◽  
General Method

Highly Efficient, Selective, and General Method for the Preparation of Meridional Homo- and Heteroleptic Tris-cyclometalated Iridium Complexes

2006 ◽  
Vol 45 (8) ◽  
pp. 3155-3157 ◽  
Author(s):  
Shouquan Huo ◽  
Joseph C. Deaton ◽  
Manju Rajeswaran ◽  
William C. Lenhart
Keyword(s):  
Iridium Complexes ◽  
Highly Efficient ◽  
General Method

Copper-Catalyzed Intramolecular α-C–H Amination via Ring-Opening Cyclization Strategy to Quinazolin-4-ones: Development and Application in Rutaecarpine Synthesis

Synthesis ◽  
2019 ◽  
Vol 51 (16) ◽  
pp. 3160-3170
Author(s):  
Srilaxmi M. Patel ◽  
Harika Chada ◽  
Sonali Biswal ◽  
Sonika Sharma ◽  
Duddu S. Sharada
Keyword(s):  
Ring Opening ◽  
Functional Group ◽  
Bond Cleavage ◽  
Isatoic Anhydride ◽  
General Method

A copper-catalyzed intramolecular α-C–H amination has been developed for the synthesis of quinazolin-4(3H)-one derivatives from commercially available isatoic anhydride and primary and secondary benzylamines via ring-opening cyclization (ROC). This method shows good functional group tolerance and allows access to a range of 2-aryl, 2-alkyl, and spiroquinazolinone derivatives. However, 2-methylquinazolin-4(3H)-one was synthesized from 2-amino-N-isopropylbenzamide by C–C bond cleavage, and N-benzyl-2-(methylamino)benzamide afforded 1-methyl-2-phenylquinazolin-4(1H)-one along with 2-phenylquinazolin-4(3H)-one by N–C bond cleavage for aromatization. It is the first general method to construct the potentially useful 2-methylquinazolin-4(3H)-one by copper-catalyzed intramolecular C–H amination. Also this ROC strategy has been successfully applied to the synthesis of quinazolinone alkaloid rutaecarpine.

Simple and highly efficient catalyst- and waste-free ring opening of epoxides with Na2S in water

2010 ◽  
Vol 141 (3) ◽  
pp. 323-326 ◽  
Author(s):  
Najmedin Azizi ◽  
Elham Akbari ◽  
Frough Ebrahimi ◽  
Mohammad R. Saidi
Keyword(s):  
Ring Opening ◽  
Efficient Catalyst ◽  
Free Ring ◽  
Highly Efficient ◽  
Ring Opening Of Epoxides
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