Liquid phase behaviour of 1-butyl-3-methylimidazolium 2-(2-methoxyethoxy)-ethylsulfate with organic solvents and water

2007 ◽  
Vol 9 (3) ◽  
pp. 262-266 ◽  
Author(s):  
Urszula Domańska ◽  
Andrzej Marciniak
Keyword(s):  
Liquid Phase ◽  
Organic Solvents ◽  
Phase Behaviour

Effect of organic solvents and ionic liquids on resolution of 2-epoxyhexane by whole cells ofRhodotorula glutinisin a two-liquid phase system

2013 ◽  
Vol 89 (4) ◽  
pp. 522-527 ◽  
Author(s):  
Michiaki Matsumoto ◽  
Takashi Sugimoto ◽  
Yudai Ishiguro ◽  
Hiroyuki Yamaguchi ◽  
Kazuo Kondo
Keyword(s):  
Ionic Liquids ◽  
Liquid Phase ◽  
Organic Solvents ◽  
Phase System ◽  
Whole Cells

scholarly journals Expansion of Intrinsically Disordered Proteins Increases the Range of Stability of Liquid–Liquid Phase Separation

Molecules ◽  
2020 ◽  
Vol 25 (20) ◽  
pp. 4705
Author(s):  
Adiran Garaizar ◽  
Ignacio Sanchez-Burgos ◽  
Rosana Collepardo-Guevara ◽  
Jorge R. Espinosa
Keyword(s):  
Phase Separation ◽  
Liquid Phase ◽  
Protein Interactions ◽  
Conformational Dynamics ◽  
Liquid Phase Separation ◽  
Phase Behaviour ◽  
Coarse Grained ◽  
Protein Protein Interactions ◽  
Intrinsically Disordered ◽  
Liquid Liquid Phase Separation

Proteins containing intrinsically disordered regions (IDRs) are ubiquitous within biomolecular condensates, which are liquid-like compartments within cells formed through liquid–liquid phase separation (LLPS). The sequence of amino acids of a protein encodes its phase behaviour, not only by establishing the patterning and chemical nature (e.g., hydrophobic, polar, charged) of the various binding sites that facilitate multivalent interactions, but also by dictating the protein conformational dynamics. Besides behaving as random coils, IDRs can exhibit a wide-range of structural behaviours, including conformational switching, where they transition between alternate conformational ensembles. Using Molecular Dynamics simulations of a minimal coarse-grained model for IDRs, we show that the role of protein conformation has a non-trivial effect in the liquid–liquid phase behaviour of IDRs. When an IDR transitions to a conformational ensemble enriched in disordered extended states, LLPS is enhanced. In contrast, IDRs that switch to ensembles that preferentially sample more compact and structured states show inhibited LLPS. This occurs because extended and disordered protein conformations facilitate LLPS-stabilising multivalent protein–protein interactions by reducing steric hindrance; thereby, such conformations maximize the molecular connectivity of the condensed liquid network. Extended protein configurations promote phase separation regardless of whether LLPS is driven by homotypic and/or heterotypic protein–protein interactions. This study sheds light on the link between the dynamic conformational plasticity of IDRs and their liquid–liquid phase behaviour.

Solid–Liquid Phase Equilibrium and Solubility of Dibenzo[b,d]furan and 9H-Fluoren-9-one in Organic Solvents

2012 ◽  
Vol 57 (4) ◽  
pp. 1279-1287 ◽  
Author(s):  
Yufeng Wei ◽  
Leping Dang ◽  
Xiangyang Zhang ◽  
Weimin Cui ◽  
Hongyuan Wei
Keyword(s):  
Phase Equilibrium ◽  
Liquid Phase ◽  
Organic Solvents ◽  
Solid Liquid

Role of water traces in the liquid-phase catalytic hydrochlorination of olefins in organic solvents

1998 ◽  
Vol 47 (2) ◽  
pp. 243-246 ◽  
Author(s):  
A. A. Mal'kov ◽  
I. P. Romm ◽  
I. A. Abronin
Keyword(s):  
Liquid Phase ◽  
Organic Solvents

Liquid-phase behaviour of normal spectral emissivity at 684.5 nm of some selected metals

2002 ◽  
Vol 34 (6) ◽  
pp. 669-679 ◽  
Author(s):  
Claus Cagran ◽  
Christian Brunner ◽  
Achim Seifter ◽  
Gernot Pottlacher
Keyword(s):  
Liquid Phase ◽  
Spectral Emissivity ◽  
Phase Behaviour ◽  
Normal Spectral Emissivity
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