Electrokinetic flow control in microfluidic chips using a field-effect transistor

Lab on a Chip ◽  
2006 ◽  
Vol 6 (6) ◽  
pp. 714 ◽  
Author(s):  
Keisuke Horiuchi ◽  
Prashanta Dutta
Keyword(s):  
Flow Control ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Microfluidic Chips ◽  
Electrokinetic Flow ◽  
Effect Transistor

Local Flow Control Using a Field Effect Transistor

2006 ◽  
Author(s):  
Keisuke Horiuchi ◽  
Prashanta Dutta
Keyword(s):  
Zeta Potential ◽  
Flow Control ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Low Voltage ◽  
Control Flow ◽  
Charge Condition ◽  
Lateral Direction ◽  
Local Flow ◽  
Effect Transistor

A field-effect transistor is developed on PDMS microchannel to control flow in microfluidic chips by modifying the surface charge condition. By applying a gate voltage to one side of the microchannel wall, zeta potential at that side is altered, while the zeta potential at the other side is maintained at the original value. This non-uniform zeta potential results in a secondary electroosmotic flow in lateral direction, which is used for flow control in microchannel geometries. The flow control is observed both quantitatively and qualitatively at relatively low voltage (less than 50 [V]), and this local flow control is primarily due to the leakage current through the interface between PDMS and glass layers. To verify the experimental results, a leakage capacitance model is introduced to estimate the modified zeta potential for the straight channel case, and excellent agreement is obtained between the predicted and experimental zeta potential results.

Applications of Field Effect Transistor Biosensors Integrated in Microfluidic Chips

2020 ◽  
Vol 12 (4) ◽  
pp. 427-445
Author(s):  
Lemeng Chao ◽  
Huanhuan Shi ◽  
Kaixuan Nie ◽  
Bo Dong ◽  
Jiafeng Ding ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
High Sensitivity ◽  
Cell Detection ◽  
Microfluidic Chips ◽  
Label Free ◽  
Gene Detection ◽  
Nano Technology ◽  
Effect Transistor ◽  
And Performance

With the progress of micro-nano technology, the integration of microfluidic technology with a field effect transistor (FET) sensor has made portable biosensing devices of miniaturized structure available. As compared to traditional biosensors that requires large equipment and anti-interfering detection, FET biosensors integrated in microfluidic chips are fully-closed devices with the advantages of high sensitivity and accurate target capturing. Meanwhile FET biosensors integrated in microfluidic chips can be prepared by a simple, batch-produced manufacturing process to achieve label-free electrical detection. Herein, the progress of the FET biosensors integrated in microfluidic chips is reviewed in terms of sensing principle, configuration, and performance. Especially, the applications of these integrated biosensors in the areas of cell detection, gene detection, biomacromolecule detection, ion detection and pH detection are highlighted. This review provides a certain guiding role in the design and development of FET-based biosensors.

Simulation of Gate-All-Around Tunnel Field-Effect Transistor with an n-Doped Layer

2010 ◽  
Vol E93-C (5) ◽  
pp. 540-545 ◽  
Author(s):  
Dong Seup LEE ◽  
Hong-Seon YANG ◽  
Kwon-Chil KANG ◽  
Joung-Eob LEE ◽  
Jung Han LEE ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Effect Transistor ◽  
Tunnel Field Effect Transistor

InGaAs/Si Heterojunction Tunneling Field-Effect Transistor on Silicon Substrate

2014 ◽  
Vol E97.C (7) ◽  
pp. 677-682
Author(s):  
Sung YUN WOO ◽  
Young JUN YOON ◽  
Jae HWA SEO ◽  
Gwan MIN YOO ◽  
Seongjae CHO ◽  
...  
Keyword(s):  
Silicon Substrate ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Effect Transistor

Biosensor Based on Ion-Sensitive Field-Effect Transistor Using Minimum Contact to Float-ing Gate

2019 ◽  
Vol 24 (4) ◽  
pp. 407-414
Author(s):  
Oksana V. Gubanova ◽  
◽  
Evgeniy V. Kuznetsov ◽  
Elena N. Rybachek ◽  
Alexander N. Saurov ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Effect Transistor
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