A new chiral lanthanide NMR probe for the determination of the enantiomeric purity of α-hydroxy acids and the absolute configuration of α-amino acids in water

2006 ◽  
pp. 3088-3096 ◽  
Author(s):  
Rachel S. Dickins ◽  
Alessandra Badari
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Enantiomeric Purity ◽  
Hydroxy Acids ◽  
The Absolute

scholarly journals Rapid Organocatalytic Chirality Analysis of Amines, Amino Acids, Alcohols, Amino Alcohols and Diols with Achiral Iso(thio)cyanate Probes

2021 ◽  
Author(s):  
Eryn Nelson ◽  
Jeffrey S. S. K. Formen ◽  
Christian Wolf
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Rapid Determination ◽  
Amino Alcohols ◽  
Enantioselective Synthesis ◽  
Widespread Occurrence ◽  
Chiral Compounds ◽  
New Methods ◽  
The Absolute

The widespread occurrence and significance of chiral compounds does not only require new methods for their enantioselective synthesis but also efficient tools that allow rapid determination of the absolute configuration,...

Determination of the Absolute Configuration of Amines and α-Amino Acids by1H NMR of (R)-O-Aryllactic Acid Amides†

1996 ◽  
Vol 61 (21) ◽  
pp. 7285-7290 ◽  
Author(s):  
Rafael Chinchilla ◽  
Larry R. Falvello ◽  
Carmen Nájera
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
The Absolute

scholarly journals Synthesis of enantiomerically enriched (R)-13C-labelled 2-aminoisobutyric acid (Aib) by conformational memory in the alkylation of a derivative of L-alanine

2011 ◽  
Vol 7 ◽  
pp. 1304-1309 ◽  
Author(s):  
Stephen P Fletcher ◽  
Jordi Solà ◽  
Dean Holt ◽  
Robert A Brown ◽  
Jonathan Clayden
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Enantiomeric Purity ◽  
Methyl Groups ◽  
Aminoisobutyric Acid ◽  
The Absolute ◽  
Conformational Memory ◽  
Enantioselective Alkylation ◽  
Derivatives Of

The method of Kouklovsky and coworkers for the enantioselective alkylation of cyclic N-naphthoyl derivatives of amino acids was used to introduce a 13C label into one of the two enantiotopic methyl groups of 2-aminoisobutyric acid (Aib) by retentive alkylation of L-alanine with 13CH3I. Conditions were identified for optimization of yield and enantiomeric purity, and the absolute configuration of the labelled product was established.

Determination of the absolute configuration and enantiomeric purity of alcohols from the13C-NMR spectra of the corresponding MTPA esters

Chirality ◽  
1990 ◽  
Vol 2 (3) ◽  
pp. 175-184 ◽  
Author(s):  
G. L. Lemière ◽  
J. J. Willaert ◽  
R. A. Dommisse ◽  
J. A. Lepoivre ◽  
F. C. Alderweireldt
Keyword(s):  
Absolute Configuration ◽  
Nmr Spectra ◽  
Enantiomeric Purity ◽  
The Absolute
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