Mononuclear nonheme ferric-peroxo complex in aldehyde deformylation

2005 ◽  
pp. 4529 ◽  
Author(s):  
Jamespandi Annaraj ◽  
Yumi Suh ◽  
Mi Sook Seo ◽  
Sun Ok Kim ◽  
Wonwoo Nam
Keyword(s):  
Peroxo Complex ◽  
Ferric Peroxo

Oxygen-Oxygen Bond Cleavage and Formation in Co(II) Mediated Stoichiometric O2 Reduction via the Potential Intermediacy of a Co(IV) Oxyl Radical

2018 ◽  
Author(s):  
Lucie Nurdin ◽  
Denis M. Spasyuk ◽  
Laura Fairburn ◽  
Warren Piers ◽  
Laurent Maron
Keyword(s):  
Bond Cleavage ◽  
Peroxo Complex ◽  
Oxygen Oxygen ◽  
O2 Reduction ◽  
Oxygen Bond ◽  
Pentadentate Ligand

Diprotonation of a remarkably stable, toluene soluble cobalt peroxo complex supported by a neutral, dianionic pentadentate ligand leads to facile O-O bond cleavage and production of a highly reactive Co(IV) oxyl cation intermediate that dimerizes and releases O<sub>2</sub>. These processes are relevant to both O<sub>2</sub> reduction and O<sub>2</sub> evolution and the mechanism was probed in detail both experimentally and computationally.

scholarly journals Unveiling the crucial intermediates in androgen production

2015 ◽  
Vol 112 (52) ◽  
pp. 15856-15861 ◽  
Author(s):  
Piotr J. Mak ◽  
Michael C. Gregory ◽  
Ilia G. Denisov ◽  
Stephen G. Sligar ◽  
James R. Kincaid
Keyword(s):  
Bond Cleavage ◽  
Nucleophilic Attack ◽  
Reaction Intermediates ◽  
Structural Determinants ◽  
Initial Product ◽  
Androgen Synthesis ◽  
Ferric Peroxo ◽  
Enzymatic Mechanisms ◽  
Primary Substrate

Ablation of androgen production through surgery is one strategy against prostate cancer, with the current focus placed on pharmaceutical intervention to restrict androgen synthesis selectively, an endeavor that could benefit from the enhanced understanding of enzymatic mechanisms that derives from characterization of key reaction intermediates. The multifunctional cytochrome P450 17A1 (CYP17A1) first catalyzes the typical hydroxylation of its primary substrate, pregnenolone (PREG) and then also orchestrates a remarkable C17–C20 bond cleavage (lyase) reaction, converting the 17-hydroxypregnenolone initial product to dehydroepiandrosterone, a process representing the first committed step in the biosynthesis of androgens. Now, we report the capture and structural characterization of intermediates produced during this lyase step: an initial peroxo-anion intermediate, poised for nucleophilic attack on the C20 position by a substrate-associated H-bond, and the crucial ferric peroxo-hemiacetal intermediate that precedes carbon–carbon (C-C) bond cleavage. These studies provide a rare glimpse at the actual structural determinants of a chemical transformation that carries profound physiological consequences.

Structural and Spectroscopic Characterization of a Monomeric Side-On Manganese(IV) Peroxo Complex

2012 ◽  
Vol 51 (22) ◽  
pp. 5427-5430 ◽  
Author(s):  
Chien-Ming Lee ◽  
Chi-He Chuo ◽  
Ching-Hui Chen ◽  
Cho-Chun Hu ◽  
Ming-Hsi Chiang ◽  
...  
Keyword(s):  
Spectroscopic Characterization ◽  
Peroxo Complex

Molybdenum(VI)-peroxo Complex Catalyzed Oxidation of Alkylbenzenes with Hydrogen Peroxide.

ChemInform ◽  
2003 ◽  
Vol 34 (40) ◽  
Author(s):  
Subhabrata Das ◽  
Tandra Bhowmick ◽  
T. Punniyamurthy ◽  
Deepa Dey ◽  
Jayashree Nath ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Peroxo Complex ◽  
Catalyzed Oxidation

Efficient oxidation of ethyl benzene using in situ generated molybdenum acetylide oxo-peroxo complex as recyclable catalyst

2017 ◽  
Vol 531 ◽  
pp. 45-51 ◽  
Author(s):  
Sonali B. Khomane ◽  
Dhananjay S. Doke ◽  
M.K. Dongare ◽  
S.B. Halligudi ◽  
S.B. Umbarkar
Keyword(s):  
Recyclable Catalyst ◽  
Ethyl Benzene ◽  
Peroxo Complex

scholarly journals Do two oxidants (ferric-peroxo and ferryl-oxo species) act in the biosynthesis of estrogens? A DFT calculation

RSC Advances ◽  
2018 ◽  
Vol 8 (27) ◽  
pp. 15196-15201 ◽  
Author(s):  
Xiang-Yun Wang ◽  
Hui-Min Yan ◽  
Yan-Li Han ◽  
Zhu-Xia Zhang ◽  
Xiao-Yun Zhang ◽  
...  
Keyword(s):  
Density Functional Theory ◽  
Density Functional ◽  
Dft Calculation ◽  
Density Functional Theory Calculations ◽  
Functional Theory ◽  
Two Oxidants ◽  
Ferric Peroxo

Density functional theory calculations were performed in order to reveal the mysterious catalytic step of the biosynthesis of estrogens.

Temperature-Dependent Immobilization of a Tungsten Peroxo Complex That Catalyzes the Hydroxymethoxylation of Olefins

ChemPlusChem ◽  
2015 ◽  
Vol 80 (6) ◽  
pp. 1029-1037 ◽  
Author(s):  
Jizhong Chen ◽  
Li Hua ◽  
Chen Chen ◽  
Li Guo ◽  
Ran Zhang ◽  
...  
Keyword(s):  
Peroxo Complex ◽  
Temperature Dependent

Fine Control of the Redox Reactivity of a Nonheme Iron(III)–Peroxo Complex by Binding Redox‐Inactive Metal Ions

2016 ◽  
Vol 129 (3) ◽  
pp. 819-823 ◽  
Author(s):  
Seong Hee Bae ◽  
Yong‐Min Lee ◽  
Shunichi Fukuzumi ◽  
Wonwoo Nam
Keyword(s):  
Metal Ions ◽  
Nonheme Iron ◽  
Peroxo Complex ◽  
Redox Reactivity ◽  
Fine Control
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