Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM)This paper is dedicated to Professor Heinz G. Floss on the occasion of his 70th birthday.Electronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b3/b315768g/

2004 ◽  
pp. 516 ◽  
Author(s):  
T. H. Samuel Tan ◽  
David T. Hickman ◽  
Jordi Morral ◽  
Ian G. Beadham ◽  
Jason Micklefield
Keyword(s):  
Nucleic Acid ◽  
Supplementary Information ◽  
Nucleic Acid Binding ◽  
Binding Properties

scholarly journals A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55Gag polyprotein alters nucleic acid binding properties

2017 ◽  
Vol 130 ◽  
pp. 137-145 ◽  
Author(s):  
Maria C. Bewley ◽  
Lisa Reinhart ◽  
Matthew S. Stake ◽  
Shorena Nadaraia-Hoke ◽  
Leslie J. Parent ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Carboxyl Terminus ◽  
Nucleic Acid Binding ◽  
Affinity Tag ◽  
Binding Properties ◽  
Hiv 1

scholarly journals In Silico Analysis: Annotations about Structural and Functional Features of DUF 2726 Family Member Proteins

2016 ◽  
pp. 53-58
Author(s):  
SM Sabbir Alam ◽  
M Ruhul Amin ◽  
M Anwar Hossain
Keyword(s):  
Nucleic Acid ◽  
Nuclear Localization ◽  
Nuclear Localization Signal ◽  
Bacterial Species ◽  
Nucleic Acid Binding ◽  
Protein Families ◽  
Binding Properties ◽  
Pfam Database ◽  
Localization Signal ◽  
Functional Features

Domains of unknown functions (DUFs) are a big set of protein families within the Pfam database that includes proteins of unknown function. In the absence of functional information, proteins are classified into different families based on conserved amino acid sequences and are potentially functionally important. In Pfam database, the numbers of families of DUFs are rapidly increasing and in current the fraction of DUF families had increased to about twenty two percent of all protein families. In this study we targeted DUF2726 member proteins which are mainly present in different bacterial species of Gamma-proteobacteria and have a particular domain organization. We analyzed the protein sequences of domain DUF2726 using different computational tools and databases. We found that this domain contains a nuclear localization signal peptide, which is conserved in Escherichia spp. and Shigella spp. It were also predicted that it has nucleic acid binding properties. Analyzing protein-protein interactions functional partners associated with DUF 2726 were revealed. Protein secondary structure, transmembrane helices structure were predicted. We have found that it has gene neighbourhood and co-occurrences with protein RepA and RepB. RepA and RepB are functionally associated with replication. RepA is a replication protein and RepB is a replication regulatory protein. Presence of a nucleic acid binding properties, a nuclear localization signal (NLS) signalling peptide, and possible interaction pattern with replication proteins, conjectures its possible role as a NLS like signalling peptide.Bangladesh J Microbiol, Volume 31, Number 1-2,June-Dec 2014, pp 53-58

RPA nucleic acid-binding properties of IFI16-HIN200

2008 ◽  
Vol 1784 (7-8) ◽  
pp. 1087-1097 ◽  
Author(s):  
Hongyue Yan ◽  
Kush Dalal ◽  
Benjamin K. Hon ◽  
Philippe Youkharibache ◽  
Desmond Lau ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Binding ◽  
Binding Properties

Polyplexes based on cationic polymers with strong nucleic acid binding properties

2012 ◽  
Vol 45 (4) ◽  
pp. 459-466 ◽  
Author(s):  
Amir K. Varkouhi ◽  
Grigoris Mountrichas ◽  
Raymond M. Schiffelers ◽  
Twan Lammers ◽  
Gert Storm ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Binding ◽  
Cationic Polymers ◽  
Binding Properties

scholarly journals Dynamics of Linker Residues Modulate the Nucleic Acid Binding Properties of the HIV-1 Nucleocapsid Protein Zinc Fingers

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e102150 ◽  
Author(s):  
Loussiné Zargarian ◽  
Carine Tisné ◽  
Pierre Barraud ◽  
Xiaoqian Xu ◽  
Nelly Morellet ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleocapsid Protein ◽  
Zinc Fingers ◽  
Nucleic Acid Binding ◽  
Binding Properties ◽  
Hiv 1

scholarly journals Structural and nucleic acid binding properties of hepatitis delta virus small antigen

2017 ◽  
Vol 6 (2) ◽  
pp. 26 ◽  
Author(s):  
Carolina Alves ◽  
Hong Cheng ◽  
João Paulo Tavanez ◽  
Ana Casaca ◽  
Severin Gudima ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Hepatitis Delta Virus ◽  
Nucleic Acid Binding ◽  
Binding Properties ◽  
Hepatitis Delta ◽  
Delta Virus
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