A novel approach to carbon hollow spheres and vessels from CCl4 at low temperaturesElectronic supplementary information (ESI) available: mass and GC spectra. See http://www.rsc.org/suppdata/cc/b2/b211996j/

2003 ◽  
pp. 904-905 ◽  
Author(s):  
Yujie Xiong ◽  
Yi Xie ◽  
Zhengquan Li ◽  
Changzheng Wu ◽  
Rong Zhang
2005 ◽  
Vol 22 (1) ◽  
pp. 42-45 ◽  
Author(s):  
Jae Kwang Lee ◽  
Sang Yun Han ◽  
Seung-Kyu Park ◽  
Yong-Ki Park ◽  
Chul Wee Lee

2019 ◽  
Vol 295 ◽  
pp. 246-252 ◽  
Author(s):  
Jianbiao Wang ◽  
Chengyu Yang ◽  
Jingjing Wang ◽  
Lijing Han ◽  
Mingdeng Wei

Nano Research ◽  
2017 ◽  
Vol 11 (1) ◽  
pp. 370-382 ◽  
Author(s):  
Manasi Jambhrunkar ◽  
Meihua Yu ◽  
Hongwei Zhang ◽  
Prasanna Abbaraju ◽  
Anand Kumar Meka ◽  
...  

2016 ◽  
Author(s):  
Stephen G. Gaffney ◽  
Jeffrey P. Townsend

ABSTRACTSummaryPathScore quantifies the level of enrichment of somatic mutations within curated pathways, applying a novel approach that identifies pathways enriched across patients. The application provides several user-friendly, interactive graphic interfaces for data exploration, including tools for comparing pathway effect sizes, significance, gene-set overlap and enrichment differences between projects.Availability and ImplementationWeb application available at pathscore.publichealth.yale.edu. Site implemented in Python and MySQL, with all major browsers supported. Source code available at github.com/sggaffney/pathscore with a GPLv3 [email protected] InformationAdditional documentation can be found at http://pathscore.publichealth.yale.edu/faq.


2004 ◽  
Vol 33 (5) ◽  
pp. 532-533 ◽  
Author(s):  
Liang Shi ◽  
Yunle Gu ◽  
Luyang Chen ◽  
Zeheng Yang ◽  
Jianhua Ma ◽  
...  

2019 ◽  
Author(s):  
Raphaël Mourad

Abstract Motivation The three dimensions (3D) genome is essential to numerous key processes such as the regulation of gene expression and the replication-timing program. In vertebrates, chromatin looping is often mediated by CTCF, and marked by CTCF motif pairs in convergent orientation. Comparative high-throughput sequencing technique (Hi-C) recently revealed that chromatin looping evolves across species. However, Hi-C experiments are complex and costly, which currently limits their use for evolutionary studies over a large number of species. Results Here, we propose a novel approach to study the 3D genome evolution in vertebrates using the genomic sequence only, e.g. without the need for Hi-C data. The approach is simple and relies on comparing the distances between convergent and divergent CTCF motifs by computing a ratio we named the 3D ratio or ‘3DR’. We show that 3DR is a powerful statistic to detect CTCF looping encoded in the human genome sequence, thus reflecting strong evolutionary constraints encoded in DNA and associated with the 3D genome. When comparing vertebrate genomes, our results reveal that 3DR which underlies CTCF looping and topologically associating domain organization evolves over time and suggest that ancestral character reconstruction can be used to infer 3DR in ancestral genomes. Availability and implementation The R code is available at https://github.com/morphos30/PhyloCTCFLooping. Supplementary information Supplementary data are available at Bioinformatics online.


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