An ICP-MS methodology using a combined high-resolution/multi-collector detector system for the measurement of total zinc and zinc isotope ratios in faecal samples from a human nutrition study

2002 ◽  
Vol 17 (11) ◽  
pp. 1502-1505 ◽  
Author(s):  
Christopher Ingle ◽  
Nicola Langford ◽  
Linda Harvey ◽  
Jack R. Dainty ◽  
Charlotte Armah ◽  
...  
Keyword(s):  
High Resolution ◽  
Isotope Ratios ◽  
Human Nutrition ◽  
Detector System ◽  
Zinc Isotope ◽  
Icp Ms ◽  
Faecal Samples ◽  
Nutrition Study

Development of a high-resolution ICP-MS method, suitable for the measurement of iron and iron isotope ratios in acid digests of faecal samples from a human nutrition study

2002 ◽  
Vol 17 (11) ◽  
pp. 1498-1501 ◽  
Author(s):  
Christopher Ingle ◽  
Nicola Langford ◽  
Linda Harvey ◽  
Jack R. Dainty ◽  
Charlotte Armah ◽  
...  
Keyword(s):  
High Resolution ◽  
Isotope Ratios ◽  
Human Nutrition ◽  
Iron Isotope ◽  
Icp Ms ◽  
Faecal Samples ◽  
Nutrition Study

In situ determination of precise stable Si isotope ratios by UV-femtosecond laser ablation high-resolution multi-collector ICP-MS

2008 ◽  
Vol 249 (1-2) ◽  
pp. 155-166 ◽  
Author(s):  
Jérôme Chmeleff ◽  
Ingo Horn ◽  
Grit Steinhoefel ◽  
Friedhelm von Blanckenburg
Keyword(s):  
Laser Ablation ◽  
High Resolution ◽  
Femtosecond Laser ◽  
Femtosecond Laser Ablation ◽  
Isotope Ratios ◽  
Icp Ms ◽  
Si Isotope

Ultratrace and isotope ratios analyses of some radionuclides by ICP-MS

2004 ◽  
Vol 92 (4-6) ◽  
Author(s):  
A. I. Helal ◽  
N. F. Zahran ◽  
M. A. Amr ◽  
A. M. Abd El-Lateef ◽  
I. I. Bashter ◽  
...  
Keyword(s):  
High Resolution ◽  
Isotope Ratios ◽  
Icp Ms

AbstractExtensive work is under way using High Resolution-ICP-MS for

Determination of silicon isotope ratios in silicate materials by high-resolution MC-ICP-MS using a sodium hydroxide sample digestion method

2006 ◽  
Vol 21 (8) ◽  
pp. 734 ◽  
Author(s):  
Sander H. J. M. van den Boorn ◽  
Pieter Z. Vroon ◽  
Coos C. van Belle ◽  
Bas van der Wagt ◽  
Johannes Schwieters ◽  
...  
Keyword(s):  
High Resolution ◽  
Sodium Hydroxide ◽  
Isotope Ratios ◽  
Silicon Isotope ◽  
Digestion Method ◽  
Sample Digestion ◽  
Icp Ms ◽  
Silicate Materials

scholarly journals Iron accumulation in the oculomotor nerve of the progressive supranuclear palsy brain

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hansol Lee ◽  
Myung Jun Lee ◽  
Eun-Joo Kim ◽  
Gi Yeong Huh ◽  
Jae-Hyeok Lee ◽  
...  
Keyword(s):  
High Resolution ◽  
Progressive Supranuclear Palsy ◽  
Oculomotor Nerve ◽  
Iron Accumulation ◽  
Blue Staining ◽  
Normal Brain ◽  
Myelinated Fiber ◽  
Healthy Controls ◽  
Icp Ms

AbstractAbnormal iron accumulation around the substantia nigra (SN) is a diagnostic indicator of Parkinsonism. This study aimed to identify iron-related microarchitectural changes around the SN of brains with progressive supranuclear palsy (PSP) via postmortem validations and in vivo magnetic resonance imaging (MRI). 7 T high-resolution MRI was applied to two postmortem brain tissues, from one normal brain and one PSP brain. Histopathological examinations were performed to demonstrate the molecular origin of the high-resolution postmortem MRI findings, by using ferric iron staining, myelin staining, and two-dimensional laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) imaging. In vivo iron-related MRI was performed on five healthy controls, five patients with Parkinson’s disease (PD), and five patients with PSP. In the postmortem examination, excessive iron deposition along the myelinated fiber at the anterior SN and third cranial nerve (oculomotor nerve) fascicles of the PSP brain was verified by LA-ICP-MS. This region corresponded to those with high R2* values and positive susceptibility from quantitative susceptibility mapping (QSM), but was less sensitive in Perls’ Prussian blue staining. In in vivo susceptibility-weighted imaging, hypointense pixels were observed in the region between the SN and red nucleus (RN) in patients with PSP, but not in healthy controls and patients with PD. R2* and QSM values of such region were significantly higher in patients with PSP compared to those in healthy controls and patients with PD as well (vs. healthy control: p = 0.008; vs. PD: p = 0.008). Thus, excessive iron accumulation along the myelinated fibers at the anterior SN and oculomotor nerve fascicles may be a pathological characteristic and crucial MR biomarker in a brain with PSP.

In situ Fe isotopic analyses of fourteen reference materials using a synthetic Cr standard for mass bias and isobaric interference corrections by femtosecond LA-MC-ICP-MS

2021 ◽  
Author(s):  
Lei Xu ◽  
Wen Zhang ◽  
Tao Luo ◽  
Jin-Hui Yang ◽  
Zhaochu Hu
Keyword(s):  
Reference Materials ◽  
Isotope Ratios ◽  
Isobaric Interference ◽  
Analytical Technique ◽  
Mass Bias ◽  
Icp Ms ◽  
Isotopic Analyses

High precise and accurate measurements of Fe isotope ratios for fourteen reference materials from the USGS, MPI-DING and CGSG were successfully carried out using a developed analytical technique by fs...

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