Applications of advanced experimental techniques: high pressure NMR and computer simulationsBased on the presentation given at Dalton Discussion No. 4, 10–13th January 2002, Kloster Banz, Germany.

2002 ◽  
pp. 633-641 ◽  
Author(s):  
Lothar Helm ◽  
André E. Merbach
Keyword(s):  
High Pressure ◽  
Experimental Techniques

scholarly journals Recent development of experimental techniques for high-pressure mineral physics under simulated mantle conditions

2006 ◽  
Vol 26 (4) ◽  
pp. 529-537 ◽  
Author(s):  
H. J. Mueller ◽  
F. R. Schilling ◽  
C. Lathe ◽  
J. Lauterjung
Keyword(s):  
High Pressure ◽  
Experimental Techniques ◽  
Mineral Physics

High pressure macromolecular crystallography for structural biology: a review

2010 ◽  
Vol 5 (5) ◽  
pp. 531-542 ◽  
Author(s):  
Katarzyna Kurpiewska ◽  
Krzysztof Lewiński
Keyword(s):  
High Pressure ◽  
Protein Folding ◽  
Structural Biology ◽  
Functional Significance ◽  
Protein Structures ◽  
Experimental Techniques ◽  
Macromolecular Crystallography ◽  
Significant Progress ◽  
Conformational Diseases ◽  
Structural Base

AbstractIn recent years, significant progress in high pressure macromolecular crystallography has been observed. It can be attributed both to the developments in experimental techniques, as well as to recognition of importance of high pressure protein studies in biochemistry and biophysics. The number of protein structures determined at pressure up to 1 GPa is growing. The unique advantages of this method can greatly improve the investigation of higher energy conformers of functional significance and our understanding of functionally important conformers, protein folding processes and the structural base of conformational diseases.

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