Thermodynamics of sulfate anion binding by macrocyclic polyammonium receptors

2001 ◽  
pp. 1765-1770 ◽  
Author(s):  
Paloma Arranz ◽  
Andrea Bencini ◽  
Antonio Bianchi ◽  
Pilar Diaz ◽  
Enrique García-España ◽  
...  
Keyword(s):  
Anion Binding ◽  
Sulfate Anion

Accessing the inaccessible: discrete multinuclear coordination complexes and selective anion binding attainable only by tethering ligands together

2017 ◽  
Vol 53 (6) ◽  
pp. 1029-1032 ◽  
Author(s):  
Basil M. Ahmed ◽  
Gellert Mezei
Keyword(s):  
Coordination Complexes ◽  
Anion Binding ◽  
Selective Binding ◽  
Sulfate Anion

The use of tethers between ligands allows for the preparation of novel multimetallic complexes, not obtainable without tethers, and leads to unexpected properties, such as selective binding of the carbonate vs. sulfate anion by nanojars.

The Ability of Thrombin Inhibitors to Reduce the Thrombin Activity Generated in Plasma on Extrinsic and Intrinsic Activation

1997 ◽  
Vol 77 (03) ◽  
pp. 498-503 ◽  
Author(s):  
D Prasa ◽  
L Svendsen ◽  
J Stürzebecher
Keyword(s):  
Active Site ◽  
Thrombin Generation ◽  
Anion Binding ◽  
Thrombin Inhibitors ◽  
Coagulation System ◽  
Thrombin Activity ◽  
Continuous Registration ◽  
High Concentrations ◽  
20 Nm ◽  
Generation Test

SummaryIn a thrombin generation test with continuous registration of thrombin activity in plasma we studied the ability of a variety of thrombin inhibitors of different type and mechanism of action to influence the activity of thrombin after activation of the coagulation system. Depending on the inhibitor, the peak of thrombin activity is delayed and/or reduced.By blocking the active site of generated thrombin inhibitors cause a concentration dependent reduction of the thrombin peak and inhibit feed-back reactions of thrombin resulting in a delay of thrombin generation. Highly potent synthetic active-site directed inhibitors (Ki ≤ 20 nM) reduce the thrombin activity formed in plasma after extrinsic or intrinsic activation with the same efficiency (IC50 0.1 - 0.6 μM) as hirudin. The delay and reduction of thrombin generation by inhibitors of the anion-binding exosite 1 of thrombin is only attributed to an inhibition of feed-back reactions of thrombin. For a 50% reduction of thrombin activity in plasma by this type of inhibitors relatively high concentrations were determined.

Formation of water chemistry in the Modonkul river under the action of mine drainage effluent

2020 ◽  
pp. 56-66
Author(s):  
Z. I. Khazheeva ◽  
S. S. Sanzhanova
Keyword(s):  
Water Chemistry ◽  
Mine Drainage ◽  
High Concentration ◽  
Catchment Basin ◽  
Sulfate Anion ◽  
Concentrated Flow ◽  
Sodium Calcium ◽  
Calcium Cation ◽  
Calcium Magnesium ◽  
The Town

The Dzhida ore field in the Zakamensk district of Buryatia features high concentration of mineralization within a small area. The Dzhida deposit is composed of complex ore. The ore field contains commercial-value primary deposits: Pervomai stockwork of molybdenum, Kholtoson tungsten lode and Inkur stockwork of tungsten. The Modonkul river catchment basin lies inside the Dzhida ore field. A real threat to the town of Zakamensk is created by manmade sand-bulk (old) tailings and slurry dump. By now, the concentrated flow of natural and man-made sand enters the low terrace and floodplain of the Modonkul river in the form of a talus train. This study is focused on the influence of the mine drainage effluent and the Inkur tributary on the water chemistry in the Modonkul river. 80 water samples were taken from the surface layer 0-0.5 m thick at five stations. Physicochemical indices of water were measured at the water sampling points, and the water chemistry was analyzed in a laboratory. In the background conditions, cations and anions in the Modonkul water chemistry range in decreasing order as follows: Са2+ > Mg2+ > Na++К+ и HCO - > SO 2- > Cl-. In the zone of mixture of natural and mine process water, the chemistry changes: from hydrocarbonate to sulfate (anion), from calcium-magnesium to sodium-calcium (cation). Downstream the natural chemistry changes to the hydrocabonate-sulfate composition, with prevailing content of calcium in cations. Iron content of water lowers 3-4 times after influx of mine effluents, while the contents of Mn, Zn, Co and Cd grow and then decrease downstream.

Cambiarenes: Single-Step Synthesis and Anion Binding of a Clip- Shaped Macrocycle with a Redox-Active Core

2019 ◽  
Author(s):  
Riley J. Petersen ◽  
Brett J. Rozeboom ◽  
Shalisa Oburn ◽  
Nolan Blythe ◽  
Tanner Rathje ◽  
...  
Keyword(s):  
Electron Density ◽  
Single Step ◽  
Anion Binding ◽  
Host Molecule ◽  
Selective Binding ◽  
The Core ◽  
Redox Active ◽  
Active Core ◽  
Guest Binding

<div>We report the synthesis of a novel macrocyclic host molecule that forms in a single step from commercially available starting materials. The core of the macrocycle backbone possesses two quinone rings and, thus, is redox-active. Host-guest binding involving the clip-shaped cavity indicates selective binding of pyridine <i>N</i>-oxides based of the electron density of and steric bulk of the anionic oxygen.</div>

scholarly journals Effects of anion binding on the deprotonation reactions of halorhodopsin.

1986 ◽  
Vol 261 (6) ◽  
pp. 2690-2696 ◽  
Author(s):  
B Schobert ◽  
J K Lanyi ◽  
D Oesterhelt
Keyword(s):  
Anion Binding

Pyrrole-bridged quinones: π-electronic systems that modulate electronic structures by tautomerism and deprotonation

2021 ◽  
Author(s):  
Shinya Sugiura ◽  
Hiromitsu Maeda
Keyword(s):  
Infrared Absorption ◽  
Electronic Structures ◽  
Near Infrared ◽  
Ion Pairing ◽  
Anion Binding ◽  
Electronic Systems

A new series of π-extended quinone derivatives containing a pyrrole bridge exhibited NH/OH-type tautomerization and anion binding along with deprotonation that induced near-infrared absorption and ion-pairing assemblies.

scholarly journals Anion binding in metal-organic frameworks

2021 ◽  
pp. 213708
Author(s):  
Xin Wu ◽  
Lauren K. Macreadie ◽  
Philip A. Gale
Keyword(s):  
Metal Organic Frameworks ◽  
Anion Binding ◽  
Metal Organic

scholarly journals Doubling the Carbonate-Binding Capacity of Nanojars by the Formation of Expanded Nanojars

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3083
Author(s):  
Wisam A. Al Isawi ◽  
Gellert Mezei
Keyword(s):  
Co2 Fixation ◽  
Binding Capacity ◽  
Coordination Complexes ◽  
Anion Binding ◽  
Ionization Mass ◽  
X Ray ◽  
Carbonate Ion ◽  
Carbonate Ions ◽  
Supramolecular Coordination ◽  
Hydration Energies

Anion binding and extraction from solutions is currently a dynamic research topic in the field of supramolecular chemistry. A particularly challenging task is the extraction of anions with large hydration energies, such as the carbonate ion. Carbonate-binding complexes are also receiving increased interest due to their relevance to atmospheric CO2 fixation. Nanojars are a class of self-assembled, supramolecular coordination complexes that have been shown to bind highly hydrophilic anions and to extract even the most hydrophilic ones, including carbonate, from water into aliphatic solvents. Here we present an expanded nanojar that is able to bind two carbonate ions, thus doubling the previously reported carbonate-binding capacity of nanojars. The new nanojar is characterized by detailed single-crystal X-ray crystallographic studies in the solid state and electrospray ionization mass spectrometric (including tandem MS/MS) studies in solution.

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