Longitudinal changes in bone lead concentration: implications for modelling of human bone lead metabolism

2001 ◽  
Vol 3 (4) ◽  
pp. 343-351 ◽  
Author(s):  
José A. A. Brito ◽  
Fiona E. McNeill ◽  
Ian Stronach ◽  
Colin E. Webber ◽  
Sue Wells ◽  
...  
Keyword(s):  
Lead Concentration ◽  
Human Bone ◽  
Longitudinal Changes ◽  
Lead Metabolism ◽  
Bone Lead

The study of age influence on human bone lead metabolism by using a simplified model and X-ray fluorescence data

2005 ◽  
Vol 7 (11) ◽  
pp. 1069 ◽  
Author(s):  
Huiling Nie ◽  
David R. Chettle ◽  
Colin E. Webber ◽  
José A. A. Brito ◽  
Joanne M. O’Meara ◽  
...  
Keyword(s):  
Human Bone ◽  
Simplified Model ◽  
X Ray ◽  
Lead Metabolism ◽  
Bone Lead

K X-ray fluorescence measurements of bone lead concentration: the analysis of low-level data

1995 ◽  
Vol 40 (9) ◽  
pp. 1475-1485 ◽  
Author(s):  
R Kim ◽  
A Aro ◽  
A Rotnitzky ◽  
C Amarasiriwardena ◽  
H Hu
Keyword(s):  
Lead Concentration ◽  
X Ray ◽  
Low Level ◽  
Fluorescence Measurements ◽  
Bone Lead ◽  
Level Data

scholarly journals Association Between Bone-lead Concentration and Aggression in Youth From a Sub-cohort of the Birth to Twenty Cohort

2021 ◽  
Author(s):  
Nonhlanhla Tlotleng ◽  
Nisha Naicker ◽  
Angela Mathee ◽  
Andrew C. Todd ◽  
Palesa Nkomo ◽  
...  
Keyword(s):  
South Africa ◽  
Lead Exposure ◽  
Aggressive Behaviour ◽  
Lead Concentration ◽  
Blood Lead ◽  
Linear Regression Models ◽  
Children And Adolescent ◽  
Bone Lead ◽  
Aggression Questionnaire ◽  
History Of

Abstract Background: An association between blood-lead levels and aggression has been demonstrated in children and adolescent youth in South Africa. However, there are limited studies that have assessed aggression as an outcome for cumulative lead exposure using bone-lead concentration. The aim of this study was to assess the association between bone-lead concentration and aggressive behaviour among a sample of the youth in South Africa. Methods: Bone lead in 100 participants (53 males and 47 females) recruited and followed in the Birth to Twenty (BT20) Cohort were measured using 109Cd-based, K-Shell X-ray Fluorescence (KXRF). The Buss-Perry Aggression questionnaire was used to measure aggressive behaviour. Linear regression models were fitted to determine the association between aggression score for physical, verbal, anger and hostility and bone lead, adjusting for known confounders. Results: The study participants were between the ages of 23 and 24 years. A one-microgram-per-gram increase in bone lead was found to increase the score for all four scales of aggression, but significantly only for anger (β=0.2 [95% CI 0.04-0.370]). Psychosocial factors such as a history of family violence and exposure to neighbourhood crime were found to be significant predictors for aggression. Conclusion: The study provides a preliminary overview of the relationship between cumulative lead exposure and behavioural problems such as aggression. A larger sample, across exposed communities, may prove more definitive in deciding whether further investigating this association could maximize generalizability. Such information could be crucial in the drafting of policies designed to combat crime associated with youth aggression in South Africa.

Random left censoring: a second look at bone lead concentration measurements

2007 ◽  
Vol 52 (17) ◽  
pp. 5369-5378 ◽  
Author(s):  
M Popovic ◽  
H Nie ◽  
D R Chettle ◽  
F E McNeill
Keyword(s):  
Lead Concentration ◽  
Second Look ◽  
Bone Lead ◽  
Concentration Measurements
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