Determination of linear alkylbenzene sulfonates and their polar carboxylic degradation products in sewage treatment plants by automated solid-phase extraction followed by capillary electrophoresis-mass spectrometry

The Analyst ◽  
2001 ◽  
Vol 126 (6) ◽  
pp. 825-828 ◽  
Author(s):  
J. Riu ◽  
D. Barceló
Keyword(s):  
Mass Spectrometry ◽  
Solid Phase ◽  
Degradation Products ◽  
Sewage Treatment ◽  
Phase Extraction ◽  
Linear Alkylbenzene ◽  
Sewage Treatment Plants ◽  
Linear Alkylbenzene Sulfonates ◽  
Automated Solid Phase Extraction

scholarly journals Simultaneous Determination of Pharmaceuticals by Solid-phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry: A Case Study from Sharjah Sewage Treatment Plant

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 633 ◽  
Author(s):  
Mohammad Semreen ◽  
Abdallah Shanableh ◽  
Lucy Semerjian ◽  
Hasan Alniss ◽  
Mouath Mousa ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Solid Phase ◽  
Sewage Treatment ◽  
Sewage Treatment Plant ◽  
Treatment Plant ◽  
Tandem Mass ◽  
Phase Extraction ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

The present work describes the optimization and validation of a highly selective and sensitive analytical method using solid phase extraction and liquid chromatography tandem mass spectrometry (SPE LC-MS/MS) for the determination of some frequently prescribed pharmaceuticals in urban wastewater received and treated by Sharjah sewage treatment plant (STP). The extraction efficiency of different SPE cartridges was tested and the simultaneous extraction of pharmaceuticals was successfully accomplished using hydrophilic-lipophilic-balanced reversed phase Waters® Oasis HLB cartridge (200 mg/ 6 mL) at pH 3. The analytes were separated on an Aquity BEH C18 column (1.7 µm, 2.1 mm × 150 mm) using gradient elution and mass spectrometric analysis were performed in multiple reactions monitoring (MRM) selecting two precursor ions to produce ion transition for each pharmaceutical using positive electrospray ionization (+ESI) mode. The correlation coefficient values in the linear calibration plot for each target compound exceeded 0.99 and the recovery percentages of the investigated pharmaceuticals were more than 84%. Limit of detection (LOD) varied between 0.1–1.5 ng/L and limit of quantification (LOQ) was 0.3–5 ng/L for all analytes. The precision of the method was calculated as the relative standard deviation (RSD%) of replicate measurements and was found to be in the ranges of 2.2% to 7.7% and 2.2% to 8.6% for inter and intra-day analysis, respectively. All of the obtained validation parameters satisfied the requirements and guidelines of analytical method validation.

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