Microwave-induced 1,3-dipolar intramolecular cycloadditions of N-substituted oximes, nitrones, and azomethine ylides for the chiral synthesis of functionalized nitrogen heterocycles

2001 ◽  
pp. 452-456 ◽  
Author(s):  
Qian Cheng ◽  
Wen Zhang ◽  
Yoshimichi Tagami ◽  
Takayuki Oritani
Keyword(s):  
Nitrogen Heterocycles ◽  
Azomethine Ylides ◽  
Chiral Synthesis ◽  
Intramolecular Cycloadditions

Synthesis of Tetracyclic Indole-Containing Ring Systems by Intramolecular Cycloadditions of Azomethine Ylides.

ChemInform ◽  
2007 ◽  
Vol 38 (17) ◽  
Author(s):  
Iain Coldham ◽  
Benjamin C. Dobson ◽  
Andrew I. Franklin ◽  
Stephen R. Fletcher
Keyword(s):  
Azomethine Ylides ◽  
Ring Systems ◽  
Intramolecular Cycloadditions

ChemInform Abstract: Intramolecular Cycloadditions with Azomethine Ylides for the Synthesis of Metacyclophanes.

ChemInform ◽  
1987 ◽  
Vol 18 (4) ◽  
Author(s):  
W. EBERBACH ◽  
H. FRITZ ◽  
I. HEINZE ◽  
P. VON LAER ◽  
P. LINK
Keyword(s):  
Azomethine Ylides ◽  
Intramolecular Cycloadditions

Synthesis of tetracyclic indole-containing ring systems by intramolecular cycloadditions of azomethine ylides

2007 ◽  
Vol 48 (5) ◽  
pp. 873-875 ◽  
Author(s):  
Iain Coldham ◽  
Benjamin C. Dobson ◽  
Andrew I. Franklin ◽  
Stephen R. Fletcher
Keyword(s):  
Azomethine Ylides ◽  
Ring Systems ◽  
Intramolecular Cycloadditions

Intramolecular cycloadditions with azomethine ylides for the synthesis of metacyclophanes

1986 ◽  
Vol 27 (34) ◽  
pp. 4003-4006 ◽  
Author(s):  
W. Eberbach ◽  
H. Fritz ◽  
I. Heinze ◽  
P. von Laer ◽  
P. Link
Keyword(s):  
Azomethine Ylides ◽  
Intramolecular Cycloadditions

Hydrogen Cyanide Polymers from the Impact of Comet P/Shoemaker-Levy 9 on Jupiter

1997 ◽  
Vol 161 ◽  
pp. 179-187
Author(s):  
Clifford N. Matthews ◽  
Rose A. Pesce-Rodriguez ◽  
Shirley A. Liebman
Keyword(s):  
Amino Acids ◽  
Solar System ◽  
Hydrogen Cyanide ◽  
Nitrogen Heterocycles ◽  
Laboratory Studies ◽  
Heterogeneous Solids ◽  
The Many ◽  
Comet Halley ◽  
The Impact ◽  
By Products

AbstractHydrogen cyanide polymers – heterogeneous solids ranging in color from yellow to orange to brown to black – may be among the organic macromolecules most readily formed within the Solar System. The non-volatile black crust of comet Halley, for example, as well as the extensive orangebrown streaks in the atmosphere of Jupiter, might consist largely of such polymers synthesized from HCN formed by photolysis of methane and ammonia, the color observed depending on the concentration of HCN involved. Laboratory studies of these ubiquitous compounds point to the presence of polyamidine structures synthesized directly from hydrogen cyanide. These would be converted by water to polypeptides which can be further hydrolyzed to α-amino acids. Black polymers and multimers with conjugated ladder structures derived from HCN could also be formed and might well be the source of the many nitrogen heterocycles, adenine included, observed after pyrolysis. The dark brown color arising from the impacts of comet P/Shoemaker-Levy 9 on Jupiter might therefore be mainly caused by the presence of HCN polymers, whether originally present, deposited by the impactor or synthesized directly from HCN. Spectroscopic detection of these predicted macromolecules and their hydrolytic and pyrolytic by-products would strengthen significantly the hypothesis that cyanide polymerization is a preferred pathway for prebiotic and extraterrestrial chemistry.

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