Quantitative Fourier transform near-infrared spectroscopy in the quality control of solid pharmaceutical formulations

The Analyst ◽  
1995 ◽  
Vol 120 (9) ◽  
pp. 2361 ◽  
Author(s):  
Elena Dreassi ◽  
Giuseppe Ceramelli ◽  
Piero Corti ◽  
Maurizio Massacesi ◽  
Piero Luigi Perruccio
Keyword(s):  
Quality Control ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Pharmaceutical Formulations

scholarly journals Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Tiannv Shi ◽  
Yongmei Guan ◽  
Lihua Chen ◽  
Shiyu Huang ◽  
Weifeng Zhu ◽  
...  
Keyword(s):  
Quality Control ◽  
Infrared Spectroscopy ◽  
Production Process ◽  
Process Monitoring ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Powder Preparation ◽  
Spectroscopy Analysis ◽  
Online Process Monitoring ◽  
Online Process

Product quality control is a prerequisite for ensuring safety, effectiveness, and stability. However, because of the different strain species and fermentation processes, there was a significant difference in quality. As a result, they should be clearly distinguished in clinical use. Among them, the fermentation process is critical to achieving consistent product quality. This study aims to introduce near-infrared spectroscopy analysis technology into the production process of fermented Cordyceps powder, including strain culture, strain passage, strain fermentation, strain filtration, strain drying, strain pulverizing, and strain mixing. First, high performance liquid chromatography (HPLC) was used to measure the total nucleosides content in the production process of 30 batches of fermented Cordyceps powder, including uracil, uridine, adenine, guanosine, adenosine, and the process stability and interbatch consistency were analyzed with traditional Chinese medicine (TCM) fingerprinting, followed by the near-infrared spectroscopy (NIRS) combined with partial least squares regression (PLSR) to establish a quantitative analysis model of total nucleosides for online process monitoring of fermented Cordyceps powder preparation products. The model parameters indicate that the established model with good robustness and high measurement precision. It further clarifies that the model can be used for online process monitoring of fermented Cordyceps powder preparation products.

Simultaneous Dielectric and Fourier Transform near Infrared Spectroscopy to Monitor a Polyepoxy Curing Process

2006 ◽  
Vol 14 (3) ◽  
pp. 161-166 ◽  
Author(s):  
Alexandra Durand ◽  
Laïla Hassi ◽  
Gilbert Lachenal ◽  
Isabelle Stevenson ◽  
Gérard Seytre ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Curing Process

scholarly journals Application of near Infrared Spectroscopy to the Quality Control of Citrus Fruits and Mango

NIR news ◽  
2016 ◽  
Vol 27 (7) ◽  
pp. 4-7 ◽  
Author(s):  
Jose Blasco ◽  
Delia Lorente ◽  
Victoria Cortes ◽  
Pau Talens ◽  
Sergio Cubero ◽  
...  
Keyword(s):  
Quality Control ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Citrus Fruits
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