The analytical work of George Pearson MD, FRS (1751-1828)

1979 ◽  
Vol 16 (12) ◽  
pp. 344
Author(s):  
W. A. Campbell
Keyword(s):  
Analytical Work

PHENOLIC METABOLITES OF DL-NORGESTREL: A METHOD FOR THE REMOVAL OF 1-HYDROXYLATED METABOLITES, POTENTIAL SOURCES OF PHENOLIC ARTIFACTS

1974 ◽  
Vol 76 (4) ◽  
pp. 789-800 ◽  
Author(s):  
Samuel F. Sisenwine ◽  
Ann L. Liu ◽  
Hazel B. Kimmel ◽  
Hans W. Ruelius
Keyword(s):  
Urinary Metabolites ◽  
Ion Exchange Resin ◽  
Gas Chromatography Mass Spectrometry ◽  
Phenolic Metabolites ◽  
Hydroxylated Metabolites ◽  
Analytical Work ◽  
Potential Sources ◽  
Alkaline Conditions ◽  
Artifact Formation ◽  
Work Up

ABSTRACT The identification of 1β-hydroxynorgestrel among the urinary metabolites of dl-norgestrel and the facile transformation of this compound under mild alkaline conditions to a potentially oestrogenic phenol provide an experimental basis for the conclusion advanced by others that the oestrogens present in the urine of subjects treated with synthetic progestens are artifacts formed during analytical work-up. A method has been devised which eliminates 1-hydroxylated metabolites as potential sources of phenolic artifacts. This method is based on the reduction by NaBH4 of the 1-hydroxy-4-en-3-one grouping in the A ring thereby excluding the possibility of aromatization during later fractionation on a basic ion exchange resin that separates neutral from phenolic metabolites. In the urines of women treated with 14C-dl-nogestrel, only 0.17–0.27% of the dose is found to have phenolic properties when this method is used. Two of the phenolic metabolites, 18-homoethynyloestradiol and 16β-hydroxy-18-homoethynyloestradiol, are present in amounts smaller than 0.01 % of the dose. Without the reduction steps the percentages are noticeably higher, indicating artifact formation under alkaline conditions. Similar results were obtained with urines from African Green Monkeys (Cercopithecus Aethiops) that had been dosed with 14C-dl-norgestrel. Radiolabelled 18-homoethynyloestradiol and 16β-hydroxy-18-homoethynyloestradiol were isolated from monkey urine and their identity confirmed by gas chromatography-mass spectrometry.

CRITERIONS FOR THE EFFECTIVENESS OF SOCIALLY IMPORTANT INVESTMENT PROJECTS AND THEIR FORMULAS ADOPTED IN RUSSIAN PRACTICE

2020 ◽  
Vol 2 (8) ◽  
pp. 58-64
Author(s):  
A. F. AGEEVA ◽  
Keyword(s):  
Performance Indicators ◽  
Payback Period ◽  
Internal Rate Of Return ◽  
Investment Projects ◽  
Regulatory Documents ◽  
Project Analysis ◽  
Analytical Work ◽  
Methodological Approaches ◽  
Further Development ◽  
Selection Of

The article analyzes domestic guidelines for assessing the effectiveness of investment projects reflected in the regulatory documentation, both current and invalid. Considered are methodological approaches to calculating key performance indicators of investment projects - net discounted income, internal rate of return, discounted payback period and profitability index. The results of the analysis and recommendations for the further development of national regulatory documents for project analysis and methodological approaches to assessing the effectiveness of socially significant investment projects are presented. The results of the analytical work presented in the article are planned to be used to create a methodology for the selection of socially significant projects for the provision of state support.

scholarly journals Behavior of NSM CFRP Reinforced Concrete Columns: Experimental and Analytical Work

2021 ◽  
pp. e00589
Author(s):  
Yasmeen Taleb Obaidat ◽  
Wasim S. Barham ◽  
Ala’ Taleb Obaidat ◽  
Khaled M. Attar
Keyword(s):  
Reinforced Concrete ◽  
Concrete Columns ◽  
Reinforced Concrete Columns ◽  
Analytical Work

Contradictions in qualitative management research

2016 ◽  
Vol 11 (1) ◽  
pp. 44-64
Author(s):  
Per Richard Hansen ◽  
Jens Dorland
Keyword(s):  
Impression Management ◽  
Research Strategy ◽  
Single Individual ◽  
Management Research ◽  
Content Type ◽  
Multiple Realities ◽  
Interview Situation ◽  
Analytical Work ◽  
Management Work

Purpose – Contradictory accounts in empirical material are often perceived as deliberate “lies” or “misleading deceptions” performed in acts of impression management, or they are simply neglected. When observed in the material collected empirically, methods have been developed in order to identify and remove them from the analytical work. The purpose of this paper is to re-visit and re-introduce a dissensus-based management research strategy in order to analytically be able to work with what appear to be contradictions and misinformation in qualitative research accounts, and give them a more profound role in the understanding of management ideas, work and practices. Design/methodology/approach – A literature review is presented on consensus and dissensus orientated theories on contradictions and multiple and conflicting identities in a single individual in an ethnographic inquiry. The purpose is to analyse and reflect upon the contradictory information gathered, and how it can shed light upon important aspects of the management work and practices performed by the informant. This is done by focusing on apparent contradictions in a single interview situation from an ethnographic case study through, respectively a consensus and a dissensus perspective. Findings – The findings indicate that dealing with contradictions and inner conflicts between self-view and external demands and conditions, led the informant to the production of multiple narrative self-identities imaging multiple realities that all appeared real to the informant. Each of these realities had different and contradictory impacts on the ideas and management work and practices he presented and performed in the organisation. These findings challenge the notions of “lies”, “deception” and “misinformation” in management research, and call for a more reflexive approach to analysis work in ethnographic accounts. Originality/value – By applying consensus and dissensus-oriented theories to a single account the authors point to conditions, phenomena and relations, which most current and historic management research streams fail to see. Multiple and conflicting identities surface in a single respondent during an interview situation, creating clearly self-contradictory and conflicting narratives and practices, that all appear to be oblivious to the respondent. These multiple and contradictory narrative identities all have significant impact on the management work performed by the respondent.

Line Contact Deformation: A Cylinder Between Two Flat Plates

1981 ◽  
Vol 103 (1) ◽  
pp. 21-25 ◽  
Author(s):  
M. R. Hoeprich ◽  
H. Zantopulos
Keyword(s):  
Plane Strain ◽  
General Equation ◽  
Roller Bearing ◽  
Experimental Results ◽  
Line Contact ◽  
Contact Deformation ◽  
Flat Plates ◽  
Special Cases ◽  
Analytical Work

Various line contact deformation equations used in roller bearing technology are analyzed. Many of these deformation equations, primarily involving plane strain, are shown to be special cases of a general equation derived in this paper. Experimental results are also presented to support the results of the analytical work.

Estimating Housing Mortality with Standard Loss Curves

1986 ◽  
Vol 18 (11) ◽  
pp. 1521-1530 ◽  
Author(s):  
M E Gleeson
Keyword(s):  
Survival Data ◽  
Statistical Models ◽  
Life Tables ◽  
Time To Failure ◽  
Truncated Data ◽  
Mobile Homes ◽  
Analytical Work ◽  
Tests Of Fit

Tests of fit using one set of data on mobile homes and another on conventional housing indicate that standard loss curves, such as the Pearl-Reed and Weibull curves, can be used to approximate housing survivorship functions. This finding opens up the possibility of analytical work using standard curves and the application of time-to-failure statistical models that are based on such curves. Tests of fit of standard curves to the two housing survivorship functions using truncated data are also encouraging, suggesting means of estimating housing mortality and computing life tables with incomplete cohort survival data.

Acoustic tracking: issues affecting design, analysis and interpretation of data from movement studies

2012 ◽  
Vol 63 (4) ◽  
pp. 312 ◽  
Author(s):  
Jason Richard How ◽  
Simon de Lestang
Keyword(s):  
Acoustic Telemetry ◽  
Full Moon ◽  
Water Movement ◽  
Lunar Cycle ◽  
Time Of Day ◽  
Detection Distance ◽  
Detection Rates ◽  
Detection Frequency ◽  
Analytical Work ◽  
Power Outputs

Acoustic telemetry systems are an increasingly common way to examine the movement and behaviour of marine organisms. However, there has been little published on the methodological and analytical work associated with this technology. We tested transmitters of differing power outputs simultaneously in several trials, some lasting ~50 days, to examine the effects of power output and environmental factors (water movement, temperature, lunar cycle and time of day). There were considerable and volatile changes in detections throughout all trials. Increased water movement and temperature significantly reduced detection rates, whereas daytime and full-moon periods had significantly higher detection rates. All nine transmitters (from seven transmitter types tested) showed a sigmoidal trend between detection frequency and distance. Higher-powered transmitters had a prolonged detection distance with near-maximal detections, whereas lower-powered transmitters showed an almost immediate decline. Variation of detection frequency, transmitter type and the modelled relationship between distance and detection frequency were incorporated into a positioning trial which resulted in markedly improved position estimates over previous techniques.

Plates in Unilateral Contact With Simple Supports: Pressure Loading

1986 ◽  
Vol 53 (1) ◽  
pp. 141-145 ◽  
Author(s):  
N. J. Salamon ◽  
T. P. Pawlak ◽  
F. F. Mahmoud
Keyword(s):  
Support System ◽  
Unilateral Contact ◽  
Response Mode ◽  
Pressure Loading ◽  
Analytical Work ◽  
Simple Supports ◽  
Square Plate ◽  
Lift Off ◽  
Good Agreement ◽  
Shear Fields

The response of a square plate, simply and unilaterally supported, to pressure loading is numerically treated. The support system consists of discrete elastic springs whose stiffnesses range from near-rigid to compliant character. It is found that, except for rather low support stiffnesses, the plate will lift off the foundation. After demonstrating good agreement with a recent analytical work, the deflections and shear fields are provided. The response mode changes dramatically as the supports approach rigidity.

OBJECTIVES OF DEVELOPING ANALYTICAL ACTIVITY IN THE INVESTIGATION OF CORRUPTION CRIMES

2021 ◽  
pp. 21-31
Author(s):  
Francisco Talmaci ◽  
◽  
◽  
Keyword(s):  
Science Education ◽  
Positive Impact ◽  
National Level ◽  
Republic Of Moldova ◽  
Criminal Offenses ◽  
Analytical Work ◽  
The Republic

This article sets out the objectives of developing analytical work in investigating criminal offenses, with particular reference to preventing and combating corruption offenses in the Republic of Moldova. Also, were analyzed the changes in legislation, which had a positive impact on the analytical activity carried out by the National Anticorruption Center, and it proposes new measures for the development of this activity in terms of science, education and institutions. The results of the research outline the need to develop guidelines for the training of future intelligence analysts, the approval of a model of criminal analysis at the national level and the introduction of a new discipline of study in police faculties - criminal analysis.

The Results of Experimental testing of Technical means of Training in the System of long-term Training of athletes specializing in Martial Arts

2021 ◽  
pp. 56-61
Author(s):  
Antonina Diachenko ◽  
Yilia Palamarchuk ◽  
Mykola Maievsky ◽  
Serhii Ilchenko ◽  
Eduard Syvokhop ◽  
...  
Keyword(s):  
Martial Arts ◽  
Experimental Testing ◽  
Scientific Research ◽  
World Cup ◽  
Internet Resources ◽  
Teaching Aids ◽  
Analytical Work ◽  
Analysis And Synthesis ◽  
Technical Teaching

According to the Results of monitoring of Internet resources, analysis of Scientific-Methodical, Special and reference literature, members of the Research Group established, that the issue of implementation (determination of effectiveness) of Modern Scientific tools, as well as Technical means of Training that provide a System of long-term training of athletes specializing in Martial Arts – is devoted to an insufficient number of Scientific and Methodological works. This requires Further Scientific Research and emphasizes the relevance and Practical component of the chosen area of Research. The main Purpose of Scientific Research is to determine the effectiveness of modern Scientific tools ("VKS Katsumoto" and "Visual 3D") in the System of long-term training of wrestlers (on the example of athletes who specialize in Sambo wrestling). In the process of Research and Analytical work, the following Research methods were used: abstraction, Analysis and Synthesis, induction and deduction, modeling, mathematical and statistical, etc. As a Result of Empirical Research, the effectiveness of modern Scientific tools has been determined "VKS Katsumoto" and "Visual 3D" in the System of long-term training of athletes specializing in Sambo (Sports and Combat direction). Prospects for Further Scientific Research in the chosen direction of Research include a comparative analysis of the performance of Ukrainian sambo wrestlers at the 2021 World Cup using modern Scientific tools (Technical Teaching Aids).

Sign in / Sign up

Export Citation Format

Share Document