A new synthetic approach to 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives via enyne metathesis and the Diels–Alder reaction

2000 ◽  
pp. 503-504 ◽  
Author(s):  
Sambasivarao Kotha ◽  
Nampally Sreenivasachary
Author(s):  
Satoru Arimitsu ◽  
Gerald B Hammond

gem-Difluoro-1,7-enyne amides are suitable building blocks for the synthesis of difluorodihydropyridinones via a ring-closing metathesis reaction, and of 4,4-difluoro-3-oxoisoquinolines through a ring-closing metathesis–enyne metathesis tandem reaction. These products, in turn, undergo a Diels–Alder reaction to yield heterotricyclic systems in moderate to good yields.


1985 ◽  
Vol 16 (34) ◽  
Author(s):  
S. J. BURRELL ◽  
A. E. DEROME ◽  
M. S. EDENBOROUGH ◽  
L. M. HARWOOD ◽  
S. A. LEEMING ◽  
...  

1970 ◽  
Vol 11 (59) ◽  
pp. 5127-5128 ◽  
Author(s):  
Y. Kishi ◽  
F. Nakatsubo ◽  
M. Aratani ◽  
T. Goto ◽  
S. Inoue ◽  
...  

ChemInform ◽  
2015 ◽  
Vol 46 (47) ◽  
pp. no-no
Author(s):  
Javier Miro ◽  
Maria Sanchez-Rosello ◽  
Alvaro Sanz ◽  
Fernando Rabasa ◽  
Carlos del Pozo ◽  
...  

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