Asymmetric nucleophilic α-amino-acylation with metalated chiral amino nitriles: enantioselective synthesis of 3-substituted 5-amino-4-oxo-esters via asymmetric Michael addition

Author(s):  
Dieter Enders ◽  
John P. Shilvock ◽  
Gerhard Raabe
ChemInform ◽  
2011 ◽  
Vol 42 (16) ◽  
pp. no-no
Author(s):  
Hai-Feng Cui ◽  
Peng Li ◽  
Xiao-Wei Wang ◽  
Zhuo Chai ◽  
Ying-Quan Yang ◽  
...  

2016 ◽  
Vol 52 (12) ◽  
pp. 2537-2540 ◽  
Author(s):  
Zhong-Yan Cao ◽  
Yu-Lei Zhao ◽  
Jian Zhou

We report an unprecedented sequential Au(i)/bifunctional tertiary amine catalysis, which enables a tandem C–H functionalization of weak nucleophiles (anisoles or thiophenes) and asymmetric Michael addition for the highly enantioselective synthesis of quaternary oxindoles.


Sign in / Sign up

Export Citation Format

Share Document