A new efficient route to the phenolic derivatives of chrysene and 5-methylchrysene, precursors to dihydrodiol and diol epoxide metabolites of chrysene and 5-methylchrysene, through Suzuki cross-coupling reaction

1998 ◽  
pp. 3157-3162 ◽  
Author(s):  
Subodh Kumar
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Diol Epoxide ◽  
Cross Coupling Reaction ◽  
Efficient Route ◽  
Phenolic Derivatives ◽  
Derivatives Of

scholarly journals Synthesis of 4-Alkyl-4H-1,2,4-triazole Derivatives by Suzuki Cross-coupling Reactions and Their Luminescence Properties

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 652 ◽  
Author(s):  
Monika Olesiejuk ◽  
Agnieszka Kudelko ◽  
Marcin Swiatkowski ◽  
Rafal Kruszynski
Keyword(s):  
Ionic Liquids ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Boronic Acids ◽  
Luminescence Properties ◽  
Coupling Reactions ◽  
Triazole Derivatives ◽  
Cross Coupling Reactions ◽  
Cross Coupling Reaction ◽  
Derivatives Of

New derivatives of 4-alkyl-3,5-diaryl-4H-1,2,4-triazole were synthesized utilizing the Suzuki cross-coupling reaction. The presented methodology comprises of the preparation of bromine-containing 4-alkyl-4H-1,2,4-triazoles and their coupling with different commercially available boronic acids in the presence of ionic liquids or in conventional solvents. The obtained compounds were tested for their luminescence properties.

Synthesis of 2-TIPS-oxazol-5-ylboronic acid pinacol ester: efficient route to 5-(het)aryloxazoles via Suzuki cross-coupling reaction

Tetrahedron ◽  
2009 ◽  
Vol 65 (32) ◽  
pp. 6348-6353 ◽  
Author(s):  
Nicolas Primas ◽  
Alexandre Bouillon ◽  
Jean-Charles Lancelot ◽  
Sylvain Rault
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Cross Coupling Reaction ◽  
Efficient Route

Palladium-Catalyzed Regioselective Heck–Suzuki–Miyaura Cascade Cyclization for the Synthesis of Trisubstituted Arylideneisoquinolinones

Synlett ◽  
2019 ◽  
Vol 30 (09) ◽  
pp. 1073-1076 ◽  
Author(s):  
M. Asgari ◽  
R. Mirzazadeh ◽  
B. Larijani ◽  
P. Rashidi Ranjbar ◽  
R. Rahimi ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Cascade Cyclization ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed ◽  
Derivatives Of

An Ugi four-component reaction was used to construct propargylamide starting materials for a subsequent domino Heck–Suzuki–Miyaura cross-coupling reaction to give derivatives of 4-benzylidene-1-oxo-3,4-dihydro-1H-isoquinoline.

Palladium Nanoparticles Anchored on Magnesium Organosilicate: An Effective and Selective Catalyst for the Heck Reaction

Synthesis ◽  
2020 ◽  
Author(s):  
Nelson Luís C. Domingues ◽  
Beatriz F. dos Santos ◽  
Beatriz A. L. da Silva ◽  
Aline R. de Oliveira ◽  
Maria H. Sarragiotto ◽  
...  
Keyword(s):  
Heck Reaction ◽  
Palladium Nanoparticles ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Amorphous Solid ◽  
Selective Catalyst ◽  
Cross Coupling Reaction ◽  
Efficient Route ◽  
High Yields ◽  
Short Time

AbstractA new and effective palladium catalyst supported on a magnesium organosilicate for application in the Heck reaction is presented. A group of compounds comprising 22 examples were synthesized in moderate to high yields (up to 99%) within a short time. The palladium supported on magnesium organosilicate catalyst was characterized as an amorphous solid by SEM, containing around 33% of palladium inside the solid, and even with this low quantity of palladium, the catalyst was very efficient in the Heck reaction. Besides, based on the Scherrer equation, the crystallite size of the synthesized palladium nanoparticles was ultrasmall (around 1.3 nm). This strategy is a simple and efficient route for the formation of C–C bonds via the Heck cross-coupling reaction.

scholarly journals Synthesis and Biological Evaluation of Novel 2-Substituted ­Analogues of (–)-Pentenomycin I

Synlett ◽  
2020 ◽  
Vol 31 (05) ◽  
pp. 475-481
Author(s):  
Stavroula A. Zisopoulou ◽  
Spyridon Bousis ◽  
Jörg Haupenthal ◽  
Jennifer Herrmann ◽  
Rolf Müller ◽  
...  
Keyword(s):  
Natural Product ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Eukaryotic Cell ◽  
Biological Evaluation ◽  
Gram Positive Bacteria ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of

A library of novel 2-substituted derivatives of the antibiotic natural product pentenomycin I is presented. The new collection of analogues is divided in two main classes, 2-alkynyl- and 2-aryl- derivatives, which are accessed by the appropriate type of palladium-catalyzed cross-coupling reaction of the 2-iodo-protected pentenomycin I with suitable nucleophiles. The new derivatives were tested for their activity against certain types of bacteria and one of them, compound 8h, was found to exhibit significant inhibitory activity against several Gram-positive bacteria but also displayed cytotoxic activity against eukaryotic cell lines.

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