Determination of the Quaternary Ammonium Compounds Dequalinium and Cetylpyridinium Chlorides in Candy-based Lozenges by High-performance Liquid Chromatography

The Analyst ◽  
1997 ◽  
Vol 122 (9) ◽  
pp. 973-976 ◽  
Author(s):  
R. B. Taylor ◽  
S. Toasaksiri ◽  
R. G. Reid ◽  
D. Wood
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Quaternary Ammonium ◽  
High Performance ◽  
Quaternary Ammonium Compounds ◽  
Ammonium Compounds

Application of high performance liquid chromatography with a charged aerosol detector for the determination of quaternary ammonium compounds in disinfectants

2020 ◽  
pp. 18-27
Author(s):  
Daria A. Merkulova ◽  
◽  
Anastasia S. Ivanova ◽  
Anna D. Salimova ◽  
Sergey V. Andreev ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Ammonium Chloride ◽  
Quaternary Ammonium ◽  
Cationic Surfactants ◽  
High Performance ◽  
Charged Aerosol ◽  
Charged Aerosol Detector ◽  
Ammonium Compounds

Cationic surfactants based disinfectants have been widely used in practice for over 20 years. Despite the significant advances in analytical chemistry during this period, the determination of mixtures of several quaternary ammonium compounds in one disinfectant still causes certain difficulties. This work describes the separation in the combined presence of alkyldimethylbenzylammonium chloride, alkyldimethyl (ethylbenzyl) ammonium chloride, and dimethyldioctylammonium chloride in disinfectants using high performance liquid chromatography with a charged aerosol detector. The method was tested on model solutions and real disinfectants. The linearity range for alkyldimethylbenzylammonium chloride was from 0.03 to 0.17 %, for alkyldimethyl (ethylbenzyl) ammonium chloride – from 0.03 to 0.15 %, and from 0.01 to 0.11 % for dimethyldioctylammonium chloride. The calculated relative error of the method did not exceed 9 %. Thus, the proposed method can be used to analyze preparative forms of disinfectants containing these and other cationic surfactants.

Determination of five quaternary ammonium compounds in foodstuffs using high performance liquid chromatography-tandem mass spectrometry

2014 ◽  
Vol 6 (13) ◽  
pp. 4790-4796 ◽  
Author(s):  
Haiwei Cao ◽  
Mingqin Kang ◽  
Zhen Chen ◽  
Ling Li ◽  
Minghui Cui ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Quaternary Ammonium ◽  
High Performance ◽  
Food Samples ◽  
Quaternary Ammonium Compounds ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Ammonium Compounds

A HPLC-MS/MS was devcloped and applied for the determination of quaternary ammonium compounds in food samples.

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