scholarly journals Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation

2015 ◽  
Vol 5 (4) ◽  
pp. e548-e548 ◽  
Author(s):  
J Chiappelli ◽  
L E Hong ◽  
S A Wijtenburg ◽  
X Du ◽  
F Gaston ◽  
...  
Keyword(s):  
White Matter ◽  
Frontal White Matter

scholarly journals A Case Report of Adult-Onset Alexander Disease with a Tumor-Like Lesion in the Lateral Ventricle

2021 ◽  
pp. 355-360
Author(s):  
Tongjia Cai ◽  
Sisi Jing ◽  
Ying Li ◽  
Jianjun Wu
Keyword(s):  
White Matter ◽  
Contrast Enhancement ◽  
Medulla Oblongata ◽  
Lateral Ventricle ◽  
Brain Lesion ◽  
Alexander Disease ◽  
Adult Onset ◽  
White Matter Abnormality ◽  
Frontal White Matter ◽  
Upper Cervical

Adult-onset Alexander disease (AOAD) is an autosomal dominant progressive astrogliopathy caused by pathogenic variants in glial fibrillary acidic protein (<i>GFAP</i>). Individuals with this disorder often present with a typical neuroradiologic pattern, including frontal white matter abnormality with contrast enhancement, atrophy and signal intensity changes of the medulla oblongata and upper cervical cord on MRI. Focal lesions are rarely seen in AOAD, which causes concern for primary malignancies. This study aimed to present the case of a 37-year-old male patient initially diagnosed with an astrocytoma in the lateral ventricle that was later identified as GFAP mutation-confirmed AOAD. <i>GFAP</i> sequencing revealed a heterogeneous missense mutation point c.236G&#x3e;A. Hence, AOAD should be considered in patients with tumor-like lesion brain lesion in association with atrophy of medulla oblongata and upper cervical spinal cord, and frontal white matter abnormality with contrast enhancement.

scholarly journals Imaging mass spectrometry of frontal white matter lipid changes in human alcoholics

Alcohol ◽  
2018 ◽  
Vol 67 ◽  
pp. 51-63 ◽  
Author(s):  
Suzanne M. de la Monte ◽  
Jared Kay ◽  
Emine B. Yalcin ◽  
Jillian J. Kril ◽  
Donna Sheedy ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
White Matter ◽  
Imaging Mass Spectrometry ◽  
Frontal White Matter

scholarly journals Frontal White Matter and Cingulum Diffusion Tensor Imaging Deficits in Alcoholism

2008 ◽  
Vol 32 (6) ◽  
pp. 1001-1013 ◽  
Author(s):  
Gordon J. Harris ◽  
Sharon Kim Jaffin ◽  
Steven M. Hodge ◽  
David Kennedy ◽  
Verne S. Caviness ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
Frontal White Matter

scholarly journals Altered frontal white matter asymmetry and its implications for cognition in schizophrenia: A tractography study

2019 ◽  
Vol 22 ◽  
pp. 101781 ◽  
Author(s):  
Ainara Gómez-Gastiasoro ◽  
Leire Zubiaurre-Elorza ◽  
Javier Peña ◽  
Naroa Ibarretxe-Bilbao ◽  
Oiane Rilo ◽  
...  
Keyword(s):  
White Matter ◽  
Frontal White Matter
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