CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors

Masayuki Ishibashi; Shinya Neri; Hiroko Hashimoto; Tomoyuki Miyashita; Tatsuya Yoshida; Yuka Nakamura; Hibiki Udagawa; Keisuke Kirita; Shingo Matsumoto; Shigeki Umemura; Kiyotaka Yoh; Seiji Niho; Masahiro Tsuboi; Kenkichi Masutomi; Koichi Goto; Atsushi Ochiai; Genichiro Ishii

doi:10.1038/srep46662

CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors

Scientific Reports ◽

10.1038/srep46662 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 12

Author(s):

Masayuki Ishibashi ◽

Shinya Neri ◽

Hiroko Hashimoto ◽

Tomoyuki Miyashita ◽

Tatsuya Yoshida ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Cancer Associated Fibroblasts ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Lung Adenocarcinomas

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Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors from the Natural Origin: A Recent Perspective

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520615666150312100259 ◽

2015 ◽

Vol 15 (8) ◽

pp. 988-1011 ◽

Cited By ~ 3

Author(s):

Harun Patel ◽

Rajesh Rane ◽

Neeta Thapliyal ◽

Mahesh Palkar ◽

Mahamadhanif Shaikh ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Natural Origin ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Complex epidermal growth factor receptor mutations and their responses to tyrosine kinase inhibitors in previously untreated advanced lung adenocarcinomas

Cancer ◽

10.1002/cncr.31329 ◽

2018 ◽

Vol 124 (11) ◽

pp. 2399-2406 ◽

Cited By ~ 6

Author(s):

Bo Zhang ◽

Shuyuan Wang ◽

Jie Qian ◽

Wenjia Yang ◽

Fangfei Qian ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Lung Adenocarcinomas

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Combination strategies based on epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for cancer patients

Medicine ◽

10.1097/md.0000000000014135 ◽

2019 ◽

Vol 98 (13) ◽

pp. e14135

Author(s):

Ran Xu ◽

Hong Shao ◽

Jing Zhu ◽

Qianqian Ju ◽

Hui Shi

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Cancer Patients ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Combination Strategies ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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140PD Complex epidermal growth factor receptor (EGFR) mutations and responses to tyrosine kinase inhibitors (TKIs) in advanced lung adenocarcinomas

Journal of Thoracic Oncology ◽

10.1016/s1556-0864(18)30414-3 ◽

2018 ◽

Vol 13 (4) ◽

pp. S82

Author(s):

B. Zhang ◽

S. Wang ◽

J. Qian ◽

W. Yang ◽

F. Qian ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Egfr Mutations ◽

Epidermal Growth ◽

Lung Adenocarcinomas

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Mutations in the epidermal growth factor receptor gene and effects of EGFR-tyrosine kinase inhibitors on lung cancers

General Thoracic and Cardiovascular Surgery ◽

10.1007/s11748-007-0193-8 ◽

2008 ◽

Vol 56 (3) ◽

pp. 97-103 ◽

Cited By ~ 30

Author(s):

Takayuki Fukui ◽

Tetsuya Mitsudomi

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Receptor Gene ◽

Growth Factor Receptor ◽

Lung Cancers ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.02.067 ◽

2009 ◽

Vol 19 (8) ◽

pp. 2333-2337 ◽

Cited By ~ 75

Author(s):

Ronghui Lin ◽

Sigmond G. Johnson ◽

Peter J. Connolly ◽

Steven K. Wetter ◽

Eva Binnun ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Pyrimidine Analogues

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3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

Journal of Computer-Aided Molecular Design ◽

10.1023/b:jcam.0000004622.13865.4f ◽

2003 ◽

Vol 17 (8) ◽

pp. 475-493 ◽

Cited By ~ 42

Author(s):

Haregewein Assefa ◽

Shantaram Kamath ◽

John K. Buolamwini

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

3D Qsar ◽

Docking Studies ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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ChemInform Abstract: Synthesis of Novel Benzoxazinone Compounds as Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors.

ChemInform ◽

10.1002/chin.201301148 ◽

2013 ◽

Vol 44 (1) ◽

pp. no-no

Author(s):

Shaopeng Chen ◽

Xuemin Li ◽

Shengbiao Wan ◽

Tao Jiang

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)

Annals of Palliative Medicine ◽

10.21037/apm-21-2828 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0-0

Author(s):

Jinfei Si ◽

Xiaodong Gu ◽

Wenxian Wang ◽

Shenpeng Ying ◽

Zhengbo Song

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Egfr Mutations ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Safety and Tolerability of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors in Oncology

Drug Safety ◽

10.1007/s40264-018-0772-x ◽

2019 ◽

Vol 42 (2) ◽

pp. 181-198 ◽

Cited By ~ 15

Author(s):

Rashmi R. Shah ◽

Devron R. Shah

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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