scholarly journals Spatiotemporally and Sequentially-Controlled Drug Release from Polymer Gatekeeper–Hollow Silica Nanoparticles

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
L. Palanikumar ◽  
M. T. Jeena ◽  
Kibeom Kim ◽  
Jun Yong Oh ◽  
Chaekyu Kim ◽  
...  
Keyword(s):  
Drug Release ◽  
Silica Nanoparticles ◽  
Controlled Drug Release ◽  
Hollow Silica ◽  
Hollow Silica Nanoparticles

Porous Hollow Silica Nanoparticles as Carriers for Controlled Delivery of Ibuprofen to Small Intestine

2006 ◽  
Vol 6 (9) ◽  
pp. 3139-3144 ◽  
Author(s):  
Li-Xiong Wen ◽  
Hao-Min Ding ◽  
Jie-Xin Wang ◽  
Jian-Feng Chen
Keyword(s):  
Small Intestine ◽  
Drug Release ◽  
Silica Nanoparticles ◽  
Sol Gel ◽  
Gastric Fluid ◽  
Sustained Drug Release ◽  
Hollow Silica ◽  
The Matrix ◽  
Hollow Silica Nanoparticles ◽  
Almost All

With two different methods, ibuprofen was entrapped into porous hollow silica nanoparticles (PHSNs) carriers, which were synthesized through a sol–gel route by using CaCO3 nanoparticles as the inorganic templates. By employing pressured CO2 as the loading medium, the amount of ibuprofen that was pressed into the carriers was ∼52% higher than that by simply soaking. The drug release behaviors of the ibuprofen-loaded PHSNs were investigated in a simulated intestine juice and an artificial gastric fluid, respectively, and it demonstrated a sustained release pattern in all cases and the sample prepared under high pressure had a lower release rate in both fluids and thus owned a greater sustained drug release capacity. In the acidic artificial gastric fluid, no silica was degraded and only 16% of the loaded ibuprofen was released from the matrix in 300 min. However, much more silica was degraded in the simulated intestine juice in a shorter time and almost all the loaded ibuprofen was dissolved into the solution eventually, resulting in a quicker and complete ibuprofen release. Therefore, the PHSNs can be utilized for applications of controlled drug delivery to small intestine.

scholarly journals AuNP and ssDNA capped mesoporous silica nanoparticles for laser controlled drug release

RSC Advances ◽  
2019 ◽  
Vol 9 (60) ◽  
pp. 34958-34962 ◽  
Author(s):  
Lu Zhou ◽  
Guojie Liu ◽  
Yang Wang ◽  
Jianling Liu ◽  
Yajie Zhang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Release

Gold nanoparticles were linked to the surface of mesoporous silica through a polyA oligonucleotide and infrared stimulation controlled drug release.

DNA-capped Fe3O4/SiO2 magnetic mesoporous silica nanoparticles for potential controlled drug release and hyperthermia

RSC Advances ◽  
2015 ◽  
Vol 5 (29) ◽  
pp. 22365-22372 ◽  
Author(s):  
Yufang Zhu ◽  
Cuilian Tao
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Potential Temperature ◽  
Controlled Drug Release ◽  
Magnetic Hyperthermia ◽  
Temperature Controlled ◽  
Magnetic Mesoporous Silica

DNA-capped Fe3O4/SiO2 magnetic mesoporous silica (MMS) nanoparticles were developed for potential temperature controlled drug release and magnetic hyperthermia.

Hollow Silica Nanoparticles Penetrate the Peripheral Nerve and Enhance the Nerve Blockade from Tetrodotoxin

Nano Letters ◽  
2017 ◽  
Vol 18 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Qian Liu ◽  
Claudia M. Santamaria ◽  
Tuo Wei ◽  
Chao Zhao ◽  
Tianjiao Ji ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Silica Nanoparticles ◽  
Hollow Silica ◽  
Nerve Blockade ◽  
Hollow Silica Nanoparticles

Novel fabrication of stable Pickering emulsion and latex by hollow silica nanoparticles

2019 ◽  
Vol 553 ◽  
pp. 83-90 ◽  
Author(s):  
Yan Bao ◽  
Yuanxia Zhang ◽  
Pan Liu ◽  
Jianzhong Ma ◽  
Wenbo Zhang ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Pickering Emulsion ◽  
Hollow Silica ◽  
Hollow Silica Nanoparticles
Sign in / Sign up

Export Citation Format

Share Document