scholarly journals Knockdown of stem cell regulator Oct4A in ovarian cancer reveals cellular reprogramming associated with key regulators of cytoskeleton-extracellular matrix remodelling

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Chantel Samardzija ◽  
David W. Greening ◽  
Ruth Escalona ◽  
Maoshan Chen ◽  
Maree Bilandzic ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Extracellular Matrix ◽  
Stem Cell ◽  
Cellular Reprogramming ◽  
Extracellular Matrix Remodelling

The role of biomaterials in the direction of mesenchymal stem cell properties and extracellular matrix remodelling in dermal tissue engineering

Biomaterials ◽  
2010 ◽  
Vol 31 (31) ◽  
pp. 7948-7959 ◽  
Author(s):  
Rebekka K. Schneider ◽  
Julia Anraths ◽  
Rafael Kramann ◽  
Jörg Bornemann ◽  
Manfred Bovi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Dermal Tissue ◽  
Extracellular Matrix Remodelling

Enhanced Structure and Function of Stem Cell-Derived Beta-Like Cells Cultured on Extracellular Matrix

2020 ◽  
Author(s):  
Reena Singh ◽  
Richard Tan ◽  
Clara Tran ◽  
Thomas Loudovaris ◽  
Helen E. Thomas ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Structure And Function ◽  
And Function ◽  
Cells Cultured

Recent Advances in Extracellular Matrix for Engineering Stem Cell Responses

2019 ◽  
Vol 26 (34) ◽  
pp. 6321-6338 ◽  
Author(s):  
Shuaimeng Guan ◽  
Kun Zhang ◽  
Jingan Li
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Attachment ◽  
Biological Significance ◽  
Engineering Application ◽  
Advanced Medical Technology ◽  
Challenges And Opportunities ◽  
Physical Functions ◽  
Differential Ability

Stem cell transplantation is an advanced medical technology, which brings hope for the treatment of some difficult diseases in the clinic. Attributed to its self-renewal and differential ability, stem cell research has been pushed to the forefront of regenerative medicine and has become a hot topic in tissue engineering. The surrounding extracellular matrix has physical functions and important biological significance in regulating the life activities of cells, which may play crucial roles for in situ inducing specific differentiation of stem cells. In this review, we discuss the stem cells and their engineering application, and highlight the control of the fate of stem cells, we offer our perspectives on the various challenges and opportunities facing the use of the components of extracellular matrix for stem cell attachment, growth, proliferation, migration and differentiation.

scholarly journals Cues from human atrial extracellular matrix enrich the atrial differentiation of human induced pluripotent stem cell-derived cardiomyocytes

2021 ◽  
Author(s):  
Fernanda C. P. Mesquita ◽  
Jacquelynn Morrissey ◽  
Po-Feng Lee ◽  
Gustavo Monnerat ◽  
Yutao Xi ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Cardiac Differentiation ◽  
Twofold Increase ◽  
Decellularized Extracellular Matrix ◽  
Induced Pluripotent

Decellularized extracellular matrix (dECM) from human atria preserves key native components that directed the cardiac differentiation of hiPSCs to an atrial-like phenotype, yielding a twofold increase of functional atrial-like cells.

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