scholarly journals Effect of agomelatine on memory deficits and hippocampal gene expression induced by chronic social defeat stress in mice

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Vincent Martin ◽  
Najib Allaïli ◽  
Marine Euvrard ◽  
Tevrasamy Marday ◽  
Armance Riffaud ◽  
...  
Keyword(s):  
Gene Expression ◽  
Social Defeat ◽  
Memory Deficits ◽  
Social Defeat Stress ◽  
Chronic Social Defeat Stress

scholarly journals Dysfunction in Ribosomal Gene Expression in the Hypothalamus and Hippocampus following Chronic Social Defeat Stress in Male Mice as Revealed by RNA-Seq

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Dmitry A. Smagin ◽  
Irina L. Kovalenko ◽  
Anna G. Galyamina ◽  
Anatoly O. Bragin ◽  
Yuriy L. Orlov ◽  
...  
Keyword(s):  
Gene Expression ◽  
Social Stress ◽  
Ribosome Biogenesis ◽  
Social Defeat ◽  
Brain Regions ◽  
Ribosomal Gene ◽  
Rna Seq ◽  
Male Mice ◽  
Social Defeat Stress ◽  
Chronic Social Defeat Stress

Chronic social defeat stress leads to the development of anxiety- and depression-like states in male mice and is accompanied by numerous molecular changes in brain. The influence of 21-day period of social stress on ribosomal gene expression in five brain regions was studied using the RNA-Seq database. MostRps, Rpl, Mprs, andMprlgenes were upregulated in the hypothalamus and downregulated in the hippocampus, which may indicate ribosomal dysfunction following chronic social defeat stress. There were no differentially expressed ribosomal genes in the ventral tegmental area, midbrain raphe nuclei, or striatum. This approach may be used to identify a pharmacological treatment of ribosome biogenesis abnormalities in the brain of patients with “ribosomopathies.”

scholarly journals Comparison of Gut Tight Junction Gene Expression in C57BL/6J and BALB/c Mice After Chronic Social Defeat Stress

2019 ◽  
Vol 53 (1) ◽  
pp. 41-46
Author(s):  
Naoko YAMAGISHI ◽  
Yasuhiro OMATA ◽  
Ayako AOKI-YOSHIDA ◽  
Naoko MORIYA ◽  
Tatsuhiko GOTO ◽  
...  
Keyword(s):  
Gene Expression ◽  
Tight Junction ◽  
Social Defeat ◽  
Social Defeat Stress ◽  
Chronic Social Defeat Stress

Downregulation of Serotonergic Gene Expression in the Raphe Nuclei of the Midbrain Under Chronic Social Defeat Stress in Male Mice

2013 ◽  
Vol 48 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Ul’yana A. Boyarskikh ◽  
Natalya P. Bondar ◽  
Maxim L. Filipenko ◽  
Natalia N. Kudryavtseva
Keyword(s):  
Gene Expression ◽  
Social Defeat ◽  
Raphe Nuclei ◽  
Male Mice ◽  
Social Defeat Stress ◽  
Chronic Social Defeat Stress ◽  
Raphé Nuclei

scholarly journals Brain histamine and oleoylethanolamide restore behavioral deficits induced by chronic social defeat stress in mice

2021 ◽  
pp. 100317
Author(s):  
Barbara Rani ◽  
Andrea Santangelo ◽  
Adele Romano ◽  
Justyna Barbara Koczwara ◽  
Marzia Friuli ◽  
...  
Keyword(s):  
Social Defeat ◽  
Social Defeat Stress ◽  
Behavioral Deficits ◽  
Brain Histamine ◽  
Chronic Social Defeat Stress
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