scholarly journals Skeletal Muscle Pump Drives Control of Cardiovascular and Postural Systems

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Ajay K. Verma ◽  
Amanmeet Garg ◽  
Da Xu ◽  
Michelle Bruner ◽  
Reza Fazel-Rezai ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Pump ◽  
Skeletal Muscle Pump

Decreased skeletal muscle pump activity in patients with postural tachycardia syndrome and low peripheral blood flow

2004 ◽  
Vol 286 (3) ◽  
pp. H1216-H1222 ◽  
Author(s):  
Julian M. Stewart ◽  
Marvin S. Medow ◽  
Leslie D. Montgomery ◽  
Kenneth McLeod
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Blood Volume ◽  
Orthostatic Intolerance ◽  
Low Flow ◽  
Peripheral Blood Flow ◽  
Muscle Pump ◽  
Postural Tachycardia ◽  
Calf Blood Flow ◽  
Skeletal Muscle Pump

Standing translocates thoracic blood volume into the dependent body. The skeletal muscle pump participates in preventing orthostatic intolerance by enhancing venous return. We investigated the hypothesis that skeletal muscle pump function is impaired in postural tachycardia (POTS) associated with low calf blood flow (low-flow POTS) and depends in general on muscle blood flow. We compared 12 subjects that have low-flow POTS with 10 controls and 7 patients that have POTS and normal calf blood flow using strain-gauge plethysmography to measure peripheral blood flow, venous capacitance, and calf muscle pump function. Blood volume was estimated by dye dilution. We found that calf circumference was reduced in low-flow POTS (32 ± 1 vs. 39 ± 3 and 43 ± 3 cm) and, compared with controls and POTS patients with normal blood flow, is related to the reduced fraction of calf venous capacity emptied during voluntary muscle contraction (ejection fraction, 0.52 ± 0.07 vs. 0.76 ± 0.07 and 0.80 ± 0.06). We found that blood flow was linearly correlated ( rp = 0.69) with calf circumference (used as a surrogate for muscle mass). Blood volume measurements were 2.2 ± 0.3 in low-flow POTS vs. 2.6 ± 0.5 in controls ( P = 0.17) and 2.4 ± 0.7 in normal-flow POTS patients. Decreased calf blood flow may reduce calf size in POTS and thereby impair the upright ejective ability of the skeletal muscle pump and further contribute to overall reduced blood flow and orthostatic intolerance in these patients.

ROLE OF THE SKELETAL MUSCLE PUMP DURING RECOVERY FROM EXERCISE 1023

1997 ◽  
Vol 29 (Supplement) ◽  
pp. 179
Author(s):  
R. Carter ◽  
D. E. Watenpaugh ◽  
W. L. Wasmund ◽  
S. L. Wasmund ◽  
M. L. Smith
Keyword(s):  
Skeletal Muscle ◽  
Muscle Pump ◽  
Skeletal Muscle Pump

Skeletal Muscle Pump vs. Respiratory Muscle Pump

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S225
Author(s):  
Jordan D. Miller ◽  
David F. Pegelow ◽  
Jerome A. Dempsey
Keyword(s):  
Skeletal Muscle ◽  
Respiratory Muscle ◽  
Muscle Pump ◽  
Skeletal Muscle Pump

scholarly journals Evaluation of a compressive-type skeletal muscle pump for cardiac assistance

1999 ◽  
Vol 67 (1) ◽  
pp. 105-111 ◽  
Author(s):  
Hisao Mizuhara ◽  
Takaaki Koshiji ◽  
Kazunobu Nishimura ◽  
Shin-ichi Nomoto ◽  
Katsuhiko Matsuda ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Pump ◽  
Cardiac Assistance ◽  
Skeletal Muscle Pump

A Compressive Type Skeletal Muscle Pump as a Biomechanical Energy Source

ASAIO Journal ◽  
1996 ◽  
Vol 42 (5) ◽  
pp. M637-641 ◽  
Author(s):  
HISAO MIZUHARA ◽  
TEIJI ODA ◽  
TAKAAKI KOSHIJI ◽  
TADASHI IKEDA ◽  
KAZUNOBU NISHIMURA ◽  
...  
Keyword(s):  
Energy Source ◽  
Skeletal Muscle ◽  
Muscle Pump ◽  
Skeletal Muscle Pump

scholarly journals Skeletal Muscle Pump Function Is Associated With Exercise Capacity in Patients With Heart Failure

2018 ◽  
Vol 82 (4) ◽  
pp. 1033-1040 ◽  
Author(s):  
Toru Kondo ◽  
Sumio Yamada ◽  
Chikako Asai ◽  
Takahiro Okumura ◽  
Daisuke Tanimura ◽  
...  
Keyword(s):  
Heart Failure ◽  
Skeletal Muscle ◽  
Exercise Capacity ◽  
Pump Function ◽  
Muscle Pump ◽  
Patients With Heart Failure ◽  
Skeletal Muscle Pump

scholarly journals Role of the Skeletal Muscle Pump in Exercise Onset Hyperemia in the Human Forearm

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Matthew Roderick Carter ◽  
Eric J Gray ◽  
Nathaniel L Rawicki ◽  
Jeffrey L Jasperse
Keyword(s):  
Skeletal Muscle ◽  
Muscle Pump ◽  
Exercise Onset ◽  
Human Forearm ◽  
Skeletal Muscle Pump

Flow-generating capability of the isolated skeletal muscle pump

1998 ◽  
Vol 274 (5) ◽  
pp. H1502-H1508 ◽  
Author(s):  
Don D. Sheriff ◽  
Richard Van Bibber
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Muscle Contraction ◽  
Vena Cava ◽  
Mechanical Forces ◽  
Muscle Pump ◽  
Arterial Blood ◽  
Contraction And Relaxation ◽  
Skeletal Muscle Pump ◽  
Shunt Tubing

We sought to test directly whether the mechanical forces produced during rhythmic muscle contraction and relaxation act on the muscle vasculature in a manner sufficient to initiate and sustain blood flow. To accomplish this goal, we evaluated the mechanical performance of the isolated skeletal muscle pump. The hindlimb skeletal muscle pump was isolated by reversibly connecting the inferior vena cava and terminal aorta with extracorporeal tubing in 15- to 20-kg anesthetized pigs ( n = 5). During electrically evoked contractions (1/s), hindlimb muscles were made to perfuse themselves by diverting the venous blood propelled out of the muscles into the shunt tubing, which had been prefilled with fresh arterial blood. This caused arterial blood to be pushed into the distal aorta and then through the muscles (shunt open, proximal aorta and vena cava clamped). In essence, the muscles perfused themselves for brief periods by driving blood around a “short-circuit” that isolates muscle from the remainder of the circulation, analogous to isolated heart-lung preparations. Because the large, short shunt offers a negligible resistance to flow, the arterial-venous pressure difference across the limbs was continuously zero, and thus the energy to drive flow through muscle could come only from the muscle pump. The increase in blood flow during normal heart-perfused contractions (with only the shunt tubing clamped) was compared with shunt-perfused contractions in which the large veins were preloaded with extra blood volume. Muscle blood flow increased by 87 ± 11 and 110 ± 21 (SE) ml/min in the first few seconds after the onset of shunt-perfused and heart-perfused contractions, respectively ( P > 0.4). We conclude that the mechanical forces produced by muscle contraction and relaxation act on the muscle vasculature in a manner sufficient to generate a significant flow of blood.

Sign in / Sign up

Export Citation Format

Share Document