scholarly journals (+)/(−)-Phaeocaulin A-D, four pairs of new enantiomeric germacrane-type sesquiterpenes from Curcuma phaeocaulis as natural nitric oxide inhibitors

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Gui-yang Xia ◽  
De-juan Sun ◽  
Jiang-hao Ma ◽  
Yue Liu ◽  
Feng Zhao ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Inhibitors

Nitric oxide inhibitors attenuate ischemic degeneration in the CA1 region of rat hippocampal slices

1996 ◽  
Vol 210 (3) ◽  
pp. 157-160 ◽  
Author(s):  
Yukitoshi Izumi ◽  
Ann M. Benz ◽  
David B. Clifford ◽  
Charles F. Zorumski
Keyword(s):  
Nitric Oxide ◽  
Hippocampal Slices ◽  
Ca1 Region ◽  
Nitric Oxide Inhibitors

Regulation of human placental fetal vessel tone: role of nitric oxide

1995 ◽  
Vol 7 (6) ◽  
pp. 1407 ◽  
Author(s):  
RG King ◽  
NM Gude ◽  
Iulio JL Di ◽  
SP Brennecke
Keyword(s):  
Nitric Oxide ◽  
Perfusion Pressure ◽  
Factors Affecting ◽  
Endothelin 1 ◽  
Calcium Dependent ◽  
Fetal Vessel ◽  
Nitric Oxide Inhibitors ◽  
Vessel Resistance ◽  
Endothelin 3

Factors affecting fetal vessel resistance have been studied in vitro in bilaterally perfused lobules of human placentae. Potent and efficacious constrictors in this preparation (in order of potency) include endothelin-1 > the thromboxane mimetic U46619 > endothelin-3 > prostaglandin F2 alpha. Inhibitors of eicosanoid synthesis did not affect fetal vessel basal perfusion pressure, nor did they potentiate the effects of the vasoconstrictor U46619. In contrast, the nitric oxide inhibitors N omega-nitro-L-arginine (NOLA), haemoglobin and methylene blue all increased fetal vessel basal perfusion pressure and also increased U46619-induced constriction. Similarly, NOLA markedly potentiated the constrictor effects of endothelin-1, angiotensin II, 5-hydroxytryptamine and bradykinin. These studies therefore provide evidence that NO is important in the maintenance of low basal fetal vessel impedance and also reduces the effects of a number of vasoconstrictor autacoids. Nitric oxide synthase (NOS) activity of human placental homogenates has been measured and shown to be mainly calcium-dependent. Human placental NOS activity was not affected by labour state but was reduced in pre-eclampsia. No evidence was found that in pre-eclampsia raised concentrations of the endogenous NOS inhibitor asymmetric dimethylarginine were responsible for the reduced placental NOS activity. Hence, these studies provide evidence that NO is an important endogenous dilator of the fetal vessels of the human placenta and that reduced NOS activity could contribute to the pathogenesis and/or effects of pre-eclampsia.

scholarly journals Effects of nitric oxide inhibitors in mice with bladder outlet obstruction

2017 ◽  
Vol 43 (2) ◽  
pp. 356-366 ◽  
Author(s):  
Marcy Lancia Pereira ◽  
Carlos Arturo Levi D’ancona ◽  
Julio Alejandro Rojas-Moscoso ◽  
Antonio Celso Saragossa Ramos Filho ◽  
Fabiola Zakia Mónica ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Bladder Outlet Obstruction ◽  
Outlet Obstruction ◽  
Nitric Oxide Inhibitors

Procognitive activity of nitric oxide inhibitors and donors in animal models

Nitric Oxide ◽  
2021 ◽  
Author(s):  
Paulina Cieślik ◽  
Leszek Kalinowski ◽  
Joanna M. Wierońska
Keyword(s):  
Nitric Oxide ◽  
Animal Models ◽  
Nitric Oxide Inhibitors

Monogalactosyldiacylglycerols, potent nitric oxide inhibitors from the marine microalgaTetraselmis chui

2013 ◽  
Vol 27 (12) ◽  
pp. 1084-1090 ◽  
Author(s):  
Arjun H. Banskota ◽  
Pamela Gallant ◽  
Roumiana Stefanova ◽  
Ronald Melanson ◽  
Stephen J.B. O’Leary
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Inhibitors

Possible role of antioxidants and nitric oxide inhibitors against carbon monoxide poisoning: Having a clear conscience because of their potential benefits

2016 ◽  
Vol 92 ◽  
pp. 3-6 ◽  
Author(s):  
Sumeyya Akyol ◽  
Sevda Yuksel ◽  
Sultan Pehlivan ◽  
Haci Kemal Erdemli ◽  
Mehmet Akif Gulec ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Carbon Monoxide ◽  
Carbon Monoxide Poisoning ◽  
Potential Benefits ◽  
Nitric Oxide Inhibitors
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