scholarly journals Therapeutic effects of human adipose tissue-derived stem cell (hADSC) transplantation on experimental autoimmune encephalomyelitis (EAE) mice

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Jia Li ◽  
Ying Chen ◽  
Zhibo Chen ◽  
Yuanyuan Huang ◽  
Dehao Yang ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Stem Cell ◽  
Experimental Autoimmune Encephalomyelitis ◽  
Human Adipose Tissue ◽  
Therapeutic Effects ◽  
Autoimmune Encephalomyelitis ◽  
Experimental Autoimmune

scholarly journals Engineered stem cell-derived microglia as therapeutic vehicle for experimental autoimmune encephalomyelitis

Gene Therapy ◽  
2013 ◽  
Vol 20 (8) ◽  
pp. 797-806 ◽  
Author(s):  
C Beutner ◽  
V Lepperhof ◽  
A Dann ◽  
B Linnartz-Gerlach ◽  
S Litwak ◽  
...  
Keyword(s):  
Stem Cell ◽  
Experimental Autoimmune Encephalomyelitis ◽  
Autoimmune Encephalomyelitis ◽  
Experimental Autoimmune

Therapeutic effects of diosgenin in experimental autoimmune encephalomyelitis

2017 ◽  
Vol 313 ◽  
pp. 152-160 ◽  
Author(s):  
Weili Liu ◽  
Mei Zhu ◽  
Zhongwang Yu ◽  
Dou Yin ◽  
Fengfeng Lu ◽  
...  
Keyword(s):  
Experimental Autoimmune Encephalomyelitis ◽  
Therapeutic Effects ◽  
Autoimmune Encephalomyelitis ◽  
Experimental Autoimmune

scholarly journals Role of Plant-Derived Natural Compounds in Experimental Autoimmune Encephalomyelitis: A Review of the Treatment Potential and Development Strategy

2021 ◽  
Vol 12 ◽  
Author(s):  
Yu-Xin Guo ◽  
Yuan Zhang ◽  
Yu-Han Gao ◽  
Si-Ying Deng ◽  
Li-Mei Wang ◽  
...  
Keyword(s):  
Natural Products ◽  
Experimental Autoimmune Encephalomyelitis ◽  
High Throughput Screening ◽  
Natural Compounds ◽  
Network Pharmacology ◽  
Therapeutic Effects ◽  
Autoimmune Encephalomyelitis ◽  
Novel Technologies ◽  
Natural Medicine ◽  
Experimental Autoimmune

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that is mainly mediated by pathological T-cells. Experimental autoimmune encephalomyelitis (EAE) is a well-known animal model of MS that is used to study the underlying mechanism and offers a theoretical basis for developing a novel therapy for MS. Good therapeutic effects have been observed after the administration of natural compounds and their derivatives as treatments for EAE. However, there has been a severe lag in the research and development of drug mechanisms related to MS. This review examines natural products that have the potential to effectively treat MS. The relevant data were consulted in order to elucidate the regulated mechanisms acting upon EAE by the flavonoids, glycosides, and triterpenoids derived from natural products. In addition, novel technologies such as network pharmacology, molecular docking, and high-throughput screening have been gradually applied in natural product development. The information provided herein can help improve targeting and timeliness for determining the specific mechanisms involved in natural medicine treatment and lay a foundation for further study.

Sign in / Sign up

Export Citation Format

Share Document