scholarly journals Neurophysiological correlates of altered response inhibition in internet gaming disorder and obsessive-compulsive disorder: Perspectives from impulsivity and compulsivity

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Minah Kim ◽  
Tak Hyung Lee ◽  
Jung-Seok Choi ◽  
Yoo Bin Kwak ◽  
Wu Jeong Hwang ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Response Inhibition ◽  
Internet Gaming Disorder ◽  
Gaming Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Internet Gaming ◽  
Altered Response

scholarly journals Neural correlates of working memory deficits and associations to response inhibition in obsessive compulsive disorder

2018 ◽  
Vol 17 ◽  
pp. 426-434 ◽  
Author(s):  
Stephan Heinzel ◽  
Christian Kaufmann ◽  
Rosa Grützmann ◽  
Robert Hummel ◽  
Julia Klawohn ◽  
...  
Keyword(s):  
Working Memory ◽  
Obsessive Compulsive Disorder ◽  
Response Inhibition ◽  
Memory Deficits ◽  
Neural Correlates ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Disturbed Monitoring and Response Inhibition in patients with Gilles De La Tourette Syndrome and Co-Morbid Obsessive Compulsive Disorder

2003 ◽  
Vol 14 (1-2) ◽  
pp. 29-37 ◽  
Author(s):  
Sandra Verena Müller ◽  
Sönke Johannes ◽  
Berdieke Wieringa ◽  
Axel Weber ◽  
Kirsten Müller-Vahl ◽  
...  
Keyword(s):  
Executive Functions ◽  
Obsessive Compulsive Disorder ◽  
Tourette Syndrome ◽  
Response Inhibition ◽  
Error Detection ◽  
Neuropsychological Tests ◽  
Cognitive Domain ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Objective:Fronto-striatal dysfunction has been discussed as underlying symptoms of Tourette syndrome (TS) with co-morbid Obsessive Compulsive Disorder (OCD). This suggests possible impairments of executive functions in this disorder, which were therefore targeted in the present study.Results:A comprehensive series of neuropsychological tests examining attention, memory and executive functions was performed in a group of 14 TS/OCD in co-occurrence with OCD patients and a matched control group.Results:While attentional and memory mechanisms were not altered, TS/OCS patients showed deficits in executive functions predominately in the areas of response inhibition and action monitoring.Conclusions:These findings provide further evidence for a substantial impairment of the frontal-striatal-thalamic-frontal circuit. We propose that the deficits in monitoring, error detection and response inhibition constitute the major impairment of TS/OCD patients in the cognitive domain.

scholarly journals Trans-diagnostic comparison of response inhibition in Tourette’s disorder and obsessive-compulsive disorder

2017 ◽  
Vol 19 (7) ◽  
pp. 527-537 ◽  
Author(s):  
Siyan Fan ◽  
Danielle C. Cath ◽  
Ysbrand D. van der Werf ◽  
Stella de Wit ◽  
Dick J. Veltman ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Response Inhibition ◽  
Tourette’S Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Tourette's Disorder

scholarly journals Altered response to risky decisions and reward in patients with obsessive–compulsive disorder

2020 ◽  
Vol 45 (2) ◽  
pp. 98-107
Author(s):  
Pedro Silva Moreira ◽  
Julian Macoveanu ◽  
Paulo Marques ◽  
Ana Coelho ◽  
Ricardo Magalhães ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Altered Response ◽  
Risky Decisions

scholarly journals Visuomotor Activation of Inhibition-Processing in Pediatric Obsessive Compulsive Disorder: A Magnetoencephalography Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Eman Nishat ◽  
Colleen Dockstader ◽  
Anne L. Wheeler ◽  
Thomas Tan ◽  
John A. E. Anderson ◽  
...  
Keyword(s):  
Task Performance ◽  
Obsessive Compulsive Disorder ◽  
Response Inhibition ◽  
Regional Differences ◽  
Children And Youth ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Medication Effects ◽  
Imaging Research ◽  
Inhibition Performance

Background: Response inhibition engages the cortico-striato-thalamo-cortical (CSTC) circuit, which has been implicated in children, and youth with obsessive compulsive disorder (OCD). This study explored whether CSTC engagement during response inhibition, measured using magnetoencephalography (MEG), differed in a sample of medication-naïve youth with OCD, compared to typically developing controls (TDC).Methods: Data was analyzed in 17 medication-naïve children and youth with OCD (11.7 ± 2.2 SD years) and 13 TDC (12.6 ± 2.2 SD years). MEG was used to localize and characterize neural activity during a Go/No-Go task. Task performance on Go/No-Go conditions and regional differences in amplitude of activity during Go and No-Go condition between OCD vs. TDC were examined using two-sample t-tests. Post-hoc analysis with Bayesian t-tests was used to estimate the certainty of outcomes.Results: No differences in Go/No-Go performance were found between OCD and TDC groups. In response to the visual cue presented during the Go condition, participants with OCD showed significantly increased amplitude of activity in the primary motor (MI) cortex compared to TDC. In addition, significantly reduced amplitude of PCu was found following successful stopping to No-Go cues in OCD vs. TDC during No-Go task performance. Bayesian t-tests indicated high probability and large effect sizes for the differences in MI and PCu amplitude found between groups.Conclusion: Our preliminary study in a small medication-naïve sample extends previous work indicating intact response inhibition in pediatric OCD. While altered neural response in the current study was found during response inhibition performance in OCD, differences localized to regions outside of the CSTC. Our findings suggest that additional imaging research in medication-naïve samples is needed to clarify regional differences associated with OCD vs. influenced by medication effects, and suggest that MEG may be sensitive to detecting such differences.

Sign in / Sign up

Export Citation Format

Share Document