scholarly journals Genome-wide analysis of long-term evolutionary domestication in Drosophila melanogaster

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Mark A. Phillips ◽  
Anthony D. Long ◽  
Zachary S. Greenspan ◽  
Lee F. Greer ◽  
Molly K. Burke ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Genome Wide Analysis ◽  
Genome Wide

scholarly journals Genome-wide analysis of Polycomb targets in Drosophila melanogaster

2006 ◽  
Vol 38 (6) ◽  
pp. 700-705 ◽  
Author(s):  
Yuri B Schwartz ◽  
Tatyana G Kahn ◽  
David A Nix ◽  
Xiao-Yong Li ◽  
Richard Bourgon ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Genome Wide Analysis ◽  
Genome Wide

scholarly journals Genome-wide analysis of promoter architecture in Drosophila melanogaster

2010 ◽  
Vol 21 (2) ◽  
pp. 182-192 ◽  
Author(s):  
R. A. Hoskins ◽  
J. M. Landolin ◽  
J. B. Brown ◽  
J. E. Sandler ◽  
H. Takahashi ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Genome Wide Analysis ◽  
Promoter Architecture ◽  
Genome Wide

scholarly journals Erratum: Corrigendum: Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Adam J. Dobson ◽  
John M. Chaston ◽  
Peter D. Newell ◽  
Leanne Donahue ◽  
Sara L. Hermann ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Genetic Determinants ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Host Genetic

scholarly journals Genome-wide analysis of Sox genes in Drosophila melanogaster

2001 ◽  
Vol 109 (2) ◽  
pp. 371-375 ◽  
Author(s):  
Frédéric Crémazy ◽  
Philippe Berta ◽  
Franck Girard
Keyword(s):  
Drosophila Melanogaster ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Sox Genes

scholarly journals Characterizing dopaminergic neuron vulnerability using Genome-wide analysis

Genetics ◽  
2021 ◽  
Author(s):  
Jacinta Davis ◽  
Claire Da Silva Santos ◽  
Narda Caudillo Zavala ◽  
Nicholas Gans ◽  
Daniel Patracuolla ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Dopaminergic Neuron ◽  
Reference Panel ◽  
Functional Validation ◽  
Mutant Analysis ◽  
Genome Wide Analysis ◽  
Progressive Loss ◽  
Genome Wide ◽  
Drosophila Genetic Reference Panel ◽  
The Brain

Abstract Parkinson’s Disease (PD) is primarily characterized by the loss of dopaminergic (DA) neurons in the brain. However, little is known about why DA neurons are selectively vulnerable to PD. To identify genes that are associated with DA neuron loss, we screened through 201 wild-caught populations of Drosophila melanogaster as part of the Drosophila Genetic Reference Panel (DGRP). Here we identify the top associated genes containing SNPs that render DA neurons vulnerable. These genes were further analyzed by using mutant analysis and tissue-specific knockdown for functional validation. We found that this loss of DA neurons caused progressive locomotor dysfunction in mutants and gene knockdown analysis. The identification of genes associated with the progressive loss of DA neurons should help to uncover factors that render these neurons vulnerable in PD, and possibly develop strategies to make these neurons more resilient.

Genome-wide analysis of phenobarbital-inducible genes in Drosophila melanogaster

2006 ◽  
Vol 15 (4) ◽  
pp. 455-464 ◽  
Author(s):  
W. Sun ◽  
V. M. Margam ◽  
L. Sun ◽  
G. Buczkowski ◽  
G. W. Bennett ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Inducible Genes

scholarly journals Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster

PLoS Genetics ◽  
2016 ◽  
Vol 12 (1) ◽  
pp. e1005616 ◽  
Author(s):  
Sibylle Chantal Vonesch ◽  
David Lamparter ◽  
Trudy F. C. Mackay ◽  
Sven Bergmann ◽  
Ernst Hafen
Keyword(s):  
Drosophila Melanogaster ◽  
Genome Wide Analysis ◽  
Genome Wide
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