scholarly journals Degeneration and energy shortage in the suprachiasmatic nucleus underlies the circadian rhythm disturbance in ApoE−/− mice: implications for Alzheimer’s disease

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Lan Zhou ◽  
Qian Gao ◽  
Meng Nie ◽  
Jing-Li Gu ◽  
Wei Hao ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Circadian Rhythm ◽  
Suprachiasmatic Nucleus ◽  
Rhythm Disturbance ◽  
Energy Shortage

Circadian Rhythm Disturbance in Agitation of Alzheimer's Disease

2021 ◽  
Vol 29 (4) ◽  
pp. S111-S113
Author(s):  
John Outen ◽  
Adam Spira ◽  
Sarah Wanigatunga ◽  
Vadim Zipunnikov ◽  
Mark Wu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Circadian Rhythm ◽  
Rhythm Disturbance

scholarly journals Circadian rhythm disturbance in agitation of Alzheimer's disease

2020 ◽  
Vol 16 (S6) ◽  
Author(s):  
Paul B. Rosenberg ◽  
Mark N. Wu ◽  
Adam P. Spira ◽  
Sarah K. Wanigatunga ◽  
Vadim Zipunnikov ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Circadian Rhythm ◽  
Rhythm Disturbance

scholarly journals Circadian rhythm disturbance in agitation of Alzheimer's disease

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Paul B. Rosenberg ◽  
John D. Outen ◽  
Adam P. Spira ◽  
Vadim Zipunnikov ◽  
Sarah K. Wanigatunga ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Circadian Rhythm ◽  
Rhythm Disturbance

scholarly journals Unique Sleep and Circadian Rhythm Dysfunction Neuroinflammatory and Immune Profiles in Alzheimer’s Disease with Mild Cognitive Impairment

2021 ◽  
pp. 1-6
Author(s):  
Jagan A. Pillai ◽  
James Bena ◽  
Lynn M. Bekris ◽  
Nancy Foldvary-Schaefer ◽  
Catherine Heinzinger ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Circadian Rhythm ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Humoral Immune ◽  
Humoral Immune Responses ◽  
Cerebrospinal Fluid Biomarkers ◽  
Circulating Markers

Sleep dysfunction has been identified in the pathophysiology of Alzheimer’s disease (AD); however, the role and mechanism of circadian rhythm dysfunction is less well understood. In a well-characterized cohort of patients with AD at the mild cognitive impairment stage (MCI-AD), we identify that circadian rhythm irregularities were accompanied by altered humoral immune responses detected in both the cerebrospinal fluid and plasma as well as alterations of cerebrospinal fluid biomarkers of neurodegeneration. On the other hand, sleep disruption was more so associated with abnormalities in circulating markers of immunity and inflammation and decrements in cognition.

Resilience in the suprachiasmatic nucleus: Implications for aging and Alzheimer's disease

2021 ◽  
Vol 147 ◽  
pp. 111258
Author(s):  
Fabian-Xosé Fernandez ◽  
Sevag Kaladchibachi ◽  
David C. Negelspach
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Suprachiasmatic Nucleus

24 hour cortisol circadian rhythm in Alzheimer's disease: Comparison with normal subjects

1994 ◽  
Vol 15 ◽  
pp. S10
Author(s):  
C.E. Rosenberg ◽  
J. Lee ◽  
D. Rowland ◽  
P.J. Whitehouse
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Circadian Rhythm ◽  
Normal Subjects
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