scholarly journals Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Tetsuji Moriyama ◽  
Shu Tanaka ◽  
Yasumune Nakayama ◽  
Masahiro Fukumoto ◽  
Kenji Tsujimura ◽  
...  
Keyword(s):  
Metabolic Network ◽  
Translational Initiation ◽  
Nucleocytoplasmic Distribution

Information on evolutionary age in redundancy of complex network

2019 ◽  
Vol 33 (27) ◽  
pp. 1950331
Author(s):  
Shiguo Deng ◽  
Henggang Ren ◽  
Tongfeng Weng ◽  
Changgui Gu ◽  
Huijie Yang
Keyword(s):  
Principal Component Analysis ◽  
Complex Networks ◽  
Metabolic Network ◽  
Complex Network ◽  
Cellular Networks ◽  
Topological Structure ◽  
Quantitative Measure ◽  
Principal Component ◽  
Evolutionary Information ◽  
Local Patterns

Evolutionary processes of many complex networks in reality are dominated by duplication and divergence. This mechanism leads to redundant structures, i.e. some nodes share most of their neighbors and some local patterns are similar, called redundancy of network. An interesting reverse problem is to discover evolutionary information from the present topological structure. We propose a quantitative measure of redundancy of network from the perspective of principal component analysis. The redundancy of a community in the empirical human metabolic network is negatively and closely related with its evolutionary age, which is consistent with that for the communities in the modeling protein–protein network. This behavior can be used to find the evolutionary difference stored in cellular networks.

scholarly journals Impacts of yeast metabolic network structure on enzyme evolution

2007 ◽  
Vol 8 (8) ◽  
pp. 407 ◽  
Author(s):  
Chenqi Lu ◽  
Ze Zhang ◽  
Lindsey Leach ◽  
MJ Kearsey ◽  
ZW Luo
Keyword(s):  
Metabolic Network ◽  
Network Structure ◽  
Enzyme Evolution
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