scholarly journals In-vivo Imaging of Magnetic Fields Induced by Transcranial Direct Current Stimulation (tDCS) in Human Brain using MRI

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Mayank V. Jog ◽  
Robert X. Smith ◽  
Kay Jann ◽  
Walter Dunn ◽  
Belen Lafon ◽  
...  
Keyword(s):  
Magnetic Fields ◽  
Human Brain ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
In Vivo Imaging ◽  
Direct Current Stimulation

scholarly journals Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo

2018 ◽  
Vol 11 (4) ◽  
pp. 727-733 ◽  
Author(s):  
Pratik Y. Chhatbar ◽  
Steven A. Kautz ◽  
Istvan Takacs ◽  
Nathan C. Rowland ◽  
Gonzalo J. Revuelta ◽  
...  
Keyword(s):  
Human Brain ◽  
Electric Fields ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation

Abstract WP139: Transcranial Direct Current Stimulation (tDCS) Generates Electric Fields (EF) at the Level of Deep Nuclei of the Human Brain in vivo

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Pratik Y Chhatbar ◽  
Steven A Kautz ◽  
Istvan Takacs ◽  
Nathan C Rowland ◽  
Gonzalo J Revuelta ◽  
...  
Keyword(s):  
Human Brain ◽  
Electric Fields ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation

scholarly journals In-vivo imaging of targeting and modulation of depression-relevant circuitry by transcranial direct current stimulation: a randomized clinical trial

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mayank. S. Jog ◽  
Elizabeth Kim ◽  
Cole Anderson ◽  
Antoni Kubicki ◽  
Rishikesh Kayathi ◽  
...  
Keyword(s):  
Magnetic Fields ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Rating Scale ◽  
Neural Circuitry ◽  
Post Treatment ◽  
Anterior Cingulate ◽  
Direct Current Stimulation ◽  
Left Dlpfc

AbstractRecent clinical trials of transcranial direct current stimulation (tDCS) in depression have shown contrasting results. Consequently, we used in-vivo neuroimaging to confirm targeting and modulation of depression-relevant neural circuitry by tDCS. Depressed participants (N = 66, Baseline Hamilton Depression Rating Scale (HDRS) 17-item scores ≥14 and <24) were randomized into Active/Sham and High-definition (HD)/Conventional (Conv) tDCS groups using a double-blind, parallel design, and received tDCS individually targeted at the left dorsolateral prefrontal cortex (DLPFC). In accordance with Ampere’s Law, tDCS currents were hypothesized to induce magnetic fields at the stimulation-target, measured in real-time using dual-echo echo-planar-imaging (DE-EPI) MRI. Additionally, the tDCS treatment trial (consisting of 12 daily 20-min sessions) was hypothesized to induce cerebral blood flow (CBF) changes post-treatment at the DLPFC target and in the reciprocally connected anterior cingulate cortex (ACC), measured using pseudo-continuous arterial spin labeling (pCASL) MRI. Significant tDCS current-induced magnetic fields were observed at the left DLPFC target for both active stimulation montages (Brodmann’s area (BA) 46: pHD = 0.048, Cohen’s dHD = 0.73; pConv = 0.018, dConv = 0.86; BA 9: pHD = 0.011, dHD = 0.92; pConv = 0.022, dConv = 0.83). Significant longitudinal CBF increases were observed (a) at the left DLPFC stimulation-target for both active montages (pHD = 3.5E−3, dHD = 0.98; pConv = 2.8E−3, dConv = 1.08), and (b) at ACC for the HD-montage only (pHD = 2.4E−3, dHD = 1.06; pConv = 0.075, dConv = 0.64). These results confirm that tDCS-treatment (a) engages the stimulation-target, and (b) modulates depression-relevant neural circuitry in depressed participants, with stronger network-modulations induced by the HD-montage. Although not primary outcomes, active HD-tDCS showed significant improvements of anhedonia relative to sham, though HDRS scores did not differ significantly between montages post-treatment.

Primary motor cortex activation by transcranial direct current stimulation in the human brain

2008 ◽  
Vol 435 (1) ◽  
pp. 56-59 ◽  
Author(s):  
Yong Hyun Kwon ◽  
Myoung-Hwan Ko ◽  
Sang Ho Ahn ◽  
Yun-Hee Kim ◽  
Jun Chan Song ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Human Brain ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Motor Cortex ◽  
Direct Current Stimulation

scholarly journals Myoinositol content in the human brain is modified by transcranial direct current stimulation in a matter of minutes: A1H-MRS study

2008 ◽  
Vol 60 (4) ◽  
pp. 782-789 ◽  
Author(s):  
M. Rango ◽  
F. Cogiamanian ◽  
S. Marceglia ◽  
B. Barberis ◽  
A. Arighi ◽  
...  
Keyword(s):  
Human Brain ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation
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