scholarly journals Effects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Ruoxi Zhang ◽  
Shuyuan Chen ◽  
Hui Zhang ◽  
Qi Liu ◽  
Jianpang Xing ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Rabbit Model ◽  
Optical Coherence

scholarly journals Optical Coherence Tomography Angiography Imaging to monitor Anti-VEGF treatment of Corneal Vascularization in a Rabbit Model

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Kavya Devarajan ◽  
Hon Shing Ong ◽  
Nyein C. Lwin ◽  
Jacqueline Chua ◽  
Leopold Schmetterer ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Imaging Technique ◽  
Anterior Segment ◽  
Rabbit Model ◽  
Saline Group ◽  
Optical Coherence ◽  
Conjunctival Injection ◽  
Anti Vegf ◽  
Significant Difference

AbstractOptical coherence tomography angiography (OCTA) is a well-established non-invasive retinal vascular imaging technique. It has been recently adapted to image the anterior segment and has shown good potential to image corneal vascularisation. The purpose of the study is to evaluate the usefulness of OCTA to monitor regression of corneal vessels following anti-VEGF (vascular endothelial growth factor) treatment using a previously established corneal vascularisation rabbit model. The regression of vessels following the treatment with aflibercept and ranibizumab anti-VEGFs using both topical instillation and sub-conjunctival injection was quantified using OCTA and compared with ICGA (indocyanine green angiography). Overall vessel density measurements using OCTA showed good correlation (r = 0.988, p < 0.001) with ICGA, with no significant difference between the two treatment groups (p = 0.795). It was also shown that OCTA provided good repeatability outcomes of the quantitative measurements. Using Bland-Altman plots, vessel growth density values between anti-VEGF treatments were compared to control saline group. It was observed that aflibercept provided longer lasting effect than ranibizumab. We also observed that in both drugs, the topical route of administration topical provided longer regression outcomes compared to one-time sub-conjunctival injection. Thereby, with this pilot study, it was demonstrated that OCTA is a reliable imaging technique to follow-up and monitor corneal vascularisation and its treatment quantitatively.

scholarly journals Diagnosis of subglottic stenosis in a rabbit model using long-range optical coherence tomography

2016 ◽  
Vol 127 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Olubunmi Ajose-Popoola ◽  
Erica Su ◽  
Ashley Hamamoto ◽  
Alex Wang ◽  
Joseph C. Jing ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Long Range ◽  
Rabbit Model ◽  
Subglottic Stenosis ◽  
Optical Coherence

Role of optical coherence tomography for flexor tendon imaging in a rabbit model

2013 ◽  
Vol 55 (5) ◽  
pp. 990-995
Author(s):  
Benjamin Chia-Meng Tay ◽  
Tzu-Hao Chow ◽  
Beng Koon Ng ◽  
Min He ◽  
Aaron Wei-Tat Gan ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Flexor Tendon ◽  
Rabbit Model ◽  
Optical Coherence

scholarly journals In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model

2008 ◽  
Vol 13 (3) ◽  
pp. 034001 ◽  
Author(s):  
Matthew Brenner ◽  
Kelly Kreuter ◽  
Johnny Ju ◽  
Sari Mahon ◽  
Lillian Tseng ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Rabbit Model ◽  
Smoke Inhalation ◽  
Optical Coherence ◽  
Large Airway

scholarly journals Detection and characterization of early plaque formations by Raman probe spectroscopy and optical coherence tomography: an in vivo study on a rabbit model

2018 ◽  
Vol 23 (01) ◽  
pp. 1 ◽  
Author(s):  
Christian Matthäus ◽  
Sebastian Dochow ◽  
Kokila D. Egodage ◽  
Bernd F. Romeike ◽  
Bernhard R. Brehm ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Rabbit Model ◽  
In Vivo Study ◽  
Optical Coherence ◽  
Probe Spectroscopy ◽  
Raman Probe
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