scholarly journals Relationship between grip strength and newly diagnosed nonalcoholic fatty liver disease in a large-scale adult population

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Ge Meng ◽  
Hongmei Wu ◽  
Liyun Fang ◽  
Chunlei Li ◽  
Fei Yu ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Grip Strength ◽  
Fatty Liver Disease ◽  
Large Scale ◽  
Adult Population ◽  
Newly Diagnosed ◽  
Nonalcoholic Fatty Liver

scholarly journals Focus on Therapeutic Strategies of Nonalcoholic Fatty Liver Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Marilena Durazzo ◽  
Paola Belci ◽  
Alessandro Collo ◽  
Enrica Grisoglio ◽  
Simona Bo
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Adult Population ◽  
Visceral Obesity ◽  
Western World ◽  
Nonalcoholic Fatty Liver ◽  
Hepatocellular Damage ◽  
General Adult Population

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the Western world (it affects 30% of the general adult population). The NAFLD encompasses a histological spectrum ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), defined by steatosis, hepatocellular damage, and lobular inflammation in individuals without significant alcohol consumption and negative viral, congenital, and autoimmune liver disease markers. Currently, NAFLD is considered an emerging epidemic in light of the dramatic increase in obesity rates. With the progressive nature of NASH and its rising prevalence there is a significant need for a specific and targeted treatments since to date there has not been any validated therapies for NAFLD other than weight loss, which is well known to have a poor long-term success rate. In recent years, visceral adipose tissue has taken an important role in NAFLD pathogenesis, and current therapeutic approaches aim at reducing visceral obesity and free fatty acid overflow to the liver. This paper is focused on the treatments used for NAFLD and the potential new therapy.

Importance of Evaluating Cardiovascular Risk and Hepatic Fibrosis in Patients With Newly Diagnosed Nonalcoholic Fatty Liver Disease

2019 ◽  
Vol 17 (5) ◽  
pp. 997-999 ◽  
Author(s):  
Maria Cristina Moreno-del Castillo ◽  
Alain Sanchez-Rodriguez ◽  
Javier Jose Hernandez-Buen Abad ◽  
Jonathan Aguirre-Valadez ◽  
Isaac Ruiz ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Hepatic Fibrosis ◽  
Fatty Liver Disease ◽  
Newly Diagnosed ◽  
Nonalcoholic Fatty Liver

scholarly journals Association between dietary raw garlic intake and newly diagnosed nonalcoholic fatty liver disease: a population-based study

2019 ◽  
Vol 181 (6) ◽  
pp. 591-602 ◽  
Author(s):  
Shunming Zhang ◽  
Yeqing Gu ◽  
Liu Wang ◽  
Qing Zhang ◽  
Li Liu ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Animal Studies ◽  
Population Based ◽  
Sensitivity Analyses ◽  
Newly Diagnosed ◽  
Nonalcoholic Fatty Liver ◽  
Frequent Consumption

Background and Aims The protective effect of garlic against nonalcoholic fatty liver disease (NAFLD) has been reported in animal studies. However, in humans, the association between garlic consumption and NAFLD is unclear. The study sought to explore the association between habitual raw garlic intake and newly diagnosed NAFLD among Chinese adults. Methods We performed a study of 11,326 men and 12,780 women aged 20–90 years. Habitual food intake was assessed using a validated and standardized 100-item food frequency questionnaire. Diagnosis of NAFLD was based on the liver ultrasonography and self-reported alcohol intake. Multiple logistic regression was used to evaluate the association of raw garlic intake with newly diagnosed NAFLD. Results The prevalence of newly diagnosed NAFLD was 28.9% in men and 10.1% in women, respectively. In men, the fully adjusted odds ratios (95% confidence interval) of having NAFLD across increasing frequency of raw garlic intake were 1.00 (reference) for <1 time/week, 0.81 (0.73, 0.90) for 1–3 times/week, 0.66 (0.54, 0.80) for 4–6 times/week, and 0.71 (0.55, 0.90) for ≥7 times/week (P for trend <0.0001). The odds ratio for NAFLD associated with each 1 g of raw garlic/1000 kcal was 0.93 (0.90, 0.97) in men. In women, no significant association between raw garlic intake and NAFLD was identified. These associations between raw garlic intake and NAFLD were consistent in several sensitivity analyses. Conclusions Frequent consumption of raw garlic is inversely associated with NAFLD in Chinese men. Further investigations are needed to confirm this finding.

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