scholarly journals Expression deregulation of mir31 and CXCL12 in two types of oral precancers and cancer: importance in progression of precancer and cancer

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Esita Chattopadhyay ◽  
Richa Singh ◽  
Anindita Ray ◽  
Roshni Roy ◽  
Navonil De Sarkar ◽  
...  
Keyword(s):  
Oral Precancers

Significance of chemiluminescence & staining in oral precancers: Our experience

2011 ◽  
Vol 3 (4) ◽  
pp. 64-65
Author(s):  
Dr Kumbhare S R Dr Kumbhare S R ◽  
◽  
Dr Taralekar S V Dr Taralekar S V
Keyword(s):  
Oral Precancers

scholarly journals Cryotherapy for oral precancers and cancers

2014 ◽  
Vol 113 (5) ◽  
pp. 272-277 ◽  
Author(s):  
Chuan-Hang Yu ◽  
Hung-Pin Lin ◽  
Shih-Jung Cheng ◽  
Andy Sun ◽  
Hsin-Ming Chen
Keyword(s):  
Oral Precancers

Histopathology of Oral Precancers

2016 ◽  
pp. 66-66
Author(s):  
KMK Masthan ◽  
N Babu ◽  
Vidyarani Shyamsundar
Keyword(s):  
Oral Precancers

scholarly journals Evaluation of Vimentin as a Potential Poor Prognostic Indicator and Salivary Biomarker for Oral Cancers and Pre-Cancers by Mass Spectrometry Based Proteomics

2021 ◽  
Author(s):  
Ananthi Sivagnanam ◽  
Vidyarani Shyamsundar ◽  
Arvind Krishnamurthy ◽  
Soundara Viveka Thangaraj ◽  
C.V Divyambika Srini ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Early Stage ◽  
Independent Set ◽  
Prognostic Indicator ◽  
High Morbidity ◽  
Tissue Samples ◽  
Oral Cancers ◽  
Normal Tissues ◽  
Aggressive Cancer ◽  
Oral Precancers

Abstract Background : Oral tongue squamous cell carcinoma (OTSCC) is an aggressive cancer with high morbidity and mortality rates, despite multimodality management. There are currently no clinically relevant molecular markers to help identify patients at a higher risk of recurrence and failure. Methods: 2D-DIGE coupled with tandem mass spectrometry was performed on tissues obtained from early staged OTSCC along with its paired apparently adjacent normal tissue samples (n=10). Top upregulated protein was validated using another independent set of tissue samples by Immunohistochemistry (n=346), comprising of retrospective early stage OTSCC (n=150) and prospective series of oral pre-cancers, normal and oral cancers (n=195). For further validation of protein expression, saliva samples collected from Oral Cancer and pre-cancer samples were analysed by ELISA (n=80). Results: We found vimentin, the mesenchymal protein to be the most upregulated protein in tongue tumour tissues compared to adjacent apparent normal tissues. Vimentin was found to be significantly overexpressed in oral pre-cancers along with cancers compared to normal tissues. Conclusion: Vimentin detection in saliva can be useful diagnostic test to detect oral precancers that may have malignant potential needing closer follow up. Salivary ELISA for vimentin can additionally be useful for disease monitoring in oral cancers.

Global spectral and local molecular connects for optical coherence tomography features to classify oral lesions towards unravelling quantitative imaging biomarkers

RSC Advances ◽  
2016 ◽  
Vol 6 (9) ◽  
pp. 7511-7520 ◽  
Author(s):  
Satarupa Banerjee ◽  
Swarnadip Chatterjee ◽  
Anji Anura ◽  
Jitamanyu Chakrabarty ◽  
Mousumi Pal ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Optical Coherence Tomography ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Quantitative Imaging ◽  
Imaging Biomarkers ◽  
Oral Lesions ◽  
Optical Coherence ◽  
Submucous Fibrosis ◽  
Oral Precancers

The biopsy based diagnosis of oral precancers like leukoplakia (OLK) and submucous fibrosis (OSF) as well as squamous cell carcinoma (OSCC) suffers from observer specific variability.

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