scholarly journals Erratum: Corrigendum: Wharton’s jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Olfat A. Hammam ◽  
Nagwa Elkhafif ◽  
Yasmeen M. Attia ◽  
Mohamed T. Mansour ◽  
Mohamed M. Elmazar ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Liver Fibrosis ◽  
Schistosoma Mansoni ◽  
Wharton’S Jelly ◽  
Wharton's Jelly

scholarly journals The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis

2009 ◽  
Vol 15 (5) ◽  
pp. 484-495 ◽  
Author(s):  
Pei-Chun Tsai ◽  
Tz-Win Fu ◽  
Yi-Ming Arthur Chen ◽  
Tsui-Ling Ko ◽  
Tien-Hua Chen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Liver Fibrosis ◽  
Rat Liver ◽  
Therapeutic Potential ◽  
Wharton’S Jelly ◽  
Wharton's Jelly ◽  
Rat Liver Fibrosis ◽  
Umbilical Mesenchymal Stem Cells

scholarly journals Wharton’s jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Olfat A. Hammam ◽  
Nagwa Elkhafif ◽  
Yasmeen M. Attia ◽  
Mohamed T. Mansour ◽  
Mohamed M. Elmazar ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Liver Fibrosis ◽  
Post Infection ◽  
Smooth Muscle Actin ◽  
Wharton’S Jelly ◽  
Alpha Smooth Muscle Actin ◽  
Beneficial Effects ◽  
Wharton's Jelly ◽  
Infection Treatment

Abstract Liver fibrosis is one of the most serious consequences of S. mansoni infection. The aim of the present study was to investigate the potential anti-fibrotic effect of human Wharton’s jelly-derived mesenchymal stem cells (WJMSCs) combined with praziquantel (PZQ) in S. mansoni-infected mice. S. mansoni-infected mice received early (8th week post infection) and late (16th week post infection) treatment with WJMSCs, alone and combined with oral PZQ. At the 10th month post infection, livers were collected for subsequent flow cytometric, histopathological, morphometric, immunohistochemical, gene expression, and gelatin zymographic studies. After transplantation, WJMSCs differentiated into functioning liver-like cells as evidenced by their ability to express human hepatocyte-specific markers. Regression of S. mansoni-induced liver fibrosis was also observed in transplanted groups, as evidenced by histopathological, morphometric, and gelatin zymographic results besides decreased expression of three essential contributors to liver fibrosis in this particular model; alpha smooth muscle actin, collagen-I, and interleukin-13. PZQ additionally enhanced the beneficial effects observed in WJMSCs-treated groups. Our results suggest that combining WJMSCs to PZQ caused better enhancement in S. mansoni-induced liver fibrosis, compared to using each alone.

Identify the role of Human Wharton's Jelly Mesenchymal Stem Cells in repairing injured uterine of rat

2021 ◽  
Vol 47 (1) ◽  
pp. 320-328
Author(s):  
Hezhu Wang ◽  
Xiaoqing Yang ◽  
Xiaojing Chen ◽  
Huihui Xie ◽  
Junxia Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Wharton’S Jelly ◽  
Wharton's Jelly

scholarly journals Exosomes derived from human umbilical cord Wharton's jelly mesenchymal stem cells ameliorate experimental lymphedema

2021 ◽  
Vol 11 (7) ◽  
Author(s):  
Zhao Ting ◽  
Yan Zhi‐xin ◽  
Tan You‐wen ◽  
Yang Fu‐ji ◽  
Sun Hui ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Umbilical Cord ◽  
Wharton’S Jelly ◽  
Human Umbilical Cord ◽  
Wharton's Jelly
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