scholarly journals Bacterial IgA protease-mediated degradation of agIgA1 and agIgA1 immune complexes as a potential therapy for IgA Nephropathy

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Li Wang ◽  
Xueying Li ◽  
Hongchun Shen ◽  
Nan Mao ◽  
Honglian Wang ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes ◽  
Iga Protease

scholarly journals Microbial IgA Protease Removes IgA Immune Complexes from Mouse Glomeruli In Vivo: Potential Therapy for IgA Nephropathy

2008 ◽  
Vol 172 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Michael E. Lamm ◽  
Steven N. Emancipator ◽  
Janet K. Robinson ◽  
Michifumi Yamashita ◽  
Hisashi Fujioka ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes ◽  
Iga Immune Complexes ◽  
Iga Protease

Estimation of Circulating Immune Complexes following Oral Challenge with Cow’s Milk in Patients with IgA Nephropathy

Nephron ◽  
1987 ◽  
Vol 47 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Masashi Sato ◽  
Kimihiro Takayama ◽  
Mikio Wakasa ◽  
Shozo Koshikawa
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes ◽  
Circulating Immune Complexes ◽  
Oral Challenge ◽  
Cow’S Milk ◽  
Cow's Milk

scholarly journals IgA nephropathy with leucocytoclastic vasculitis

2018 ◽  
Vol 46 (7) ◽  
pp. 3009-3014 ◽  
Author(s):  
Lin-Yan Wei ◽  
Chao Liu ◽  
Ya-Li Zhang ◽  
Guo-Liang Li
Keyword(s):  
Iga Nephropathy ◽  
Allergic Disease ◽  
Clinical Manifestation ◽  
Immune Complexes ◽  
Diagnosis And Treatment ◽  
Microscopic Haematuria ◽  
Leucocytoclastic Vasculitis ◽  
Rare Type ◽  
Gross Haematuria

Leucocytoclastic vasculitis is a rare type of allergic disease caused by immune complexes. IgA nephropathy is a glomerulopathy characterized by recurrent episodes of gross haematuria or microscopic haematuria and IgA deposition in the glomerular mesangial region. IgA nephropathy complicating leucocytoclastic vasculitis is rare documented. We present a case of IgA nephropathy in a 47-year-old woman with leucocytoclastic vasculitis and discuss the clinical and pathological data, aiming to promote the diagnosis and treatment of this specific clinical manifestation.

IgA nephropathy: clearance kinetics of IgA-containing immune complexes

2018 ◽  
Vol 40 (6) ◽  
pp. 539-543 ◽  
Author(s):  
Ann Chen ◽  
Sung-Sen Yang ◽  
Tsai-Jung Lin ◽  
Shuk-Man Ka
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes ◽  
Clearance Kinetics ◽  
Kinetics Of

The Role of IgA and IgG Immune Complexes in IgA Nephropathy

Nephron ◽  
1984 ◽  
Vol 36 (1) ◽  
pp. 52-59 ◽  
Author(s):  
J. Egido ◽  
J. Sancho ◽  
F. Rivera ◽  
L. Hernando
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes

Interstitial Inflammatory and Chronic Tubulointerstitial Lesions in Lupus Nephritis: Comparison with those in IgA Nephropathy

Lupus ◽  
1993 ◽  
Vol 2 (1_suppl) ◽  
pp. 261-268 ◽  
Author(s):  
Tatsuo Yamamoto ◽  
Mitsumasa Nagase ◽  
Akira Hishida ◽  
Nishio Honda
Keyword(s):  
Lupus Nephritis ◽  
Iga Nephropathy ◽  
Immune Complexes ◽  
Prognostic Significance ◽  
Underlying Disease ◽  
Inflammatory Lesions ◽  
Tubulointerstitial Lesions ◽  
Glomerular Lesions ◽  
Renal Prognosis

The significance of interstitial inflammatory and chronic tubulointerstitial lesions was studied in relation to the severity of glomerular lesions in 62 patients with lupus nephritis and 88 with IgA nephropathy. Severe interstitial inflammatory and chronic tubulointerstitial lesions were found in patients with severe glomerular lesions in both lupus nephritis and IgA nephropathy. In such cases, the serum creatinine levels at biopsy were high and the renal prognosis was poor regardless of the underlying disease (lupus nephritis or IgA nephropathy). No IgA nephropathy patients with nil or mild glomerular lesions had moderate or severe interstitial inflammatory and/or chronic tubulointerstitial lesions. In contrast, predominantly severe interstitial inflammatory lesions were found in 36% of lupus nephritis patients with nil or mild glomerular lesions. The prevalence of interstitial immune complexes deposition was markedly high in those with predominant interstitial inflammatory lesions. However, the severity of chronic tubulointerstitial lesions was mild and renal function did not deteriorate in the mean follow-up periods of 68.6 months. It is suggested that, besides the tubulointerstitial lesions attributable to the severe concomitant glomerular damage, the interstitial deposition of immune complexes per se plays a pathogenic role in the interstitial inflammatory lesions in lupus nephritis. Its prognostic significance, however, was considered to be minor.

Interaction of immune complexes with Fc receptors in mesangial cells: A potential target for the treatment of IgA nephropathy

Nephrology ◽  
1997 ◽  
Vol 3 (1) ◽  
pp. 95-101 ◽  
Author(s):  
C. GÓMEZ-GUERRERO ◽  
N. DUQUE ◽  
MJ LÓPEZ-ARMADA ◽  
MT CASADO ◽  
F. VIVANCO ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes ◽  
Mesangial Cells ◽  
Fc Receptors ◽  
Potential Target

Circulating Immune Complexes, the Concentration of Serum IgA and the Distribution of HLA Antigens in IgA Nephropathy

Nephron ◽  
1981 ◽  
Vol 29 (3-4) ◽  
pp. 170-175 ◽  
Author(s):  
J. Mustonen ◽  
A. Pasternack ◽  
H. Helin ◽  
A. Rilva ◽  
K. Penttinen ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes ◽  
Hla Antigens ◽  
Circulating Immune Complexes ◽  
Serum Iga

Detection of IgAl-Dominant Immune Complexes in Peripheral Blood Polymorphonuclear Leukocytes by Double Immunofluorescence in Patients with IgA Nephropathy

Nephron ◽  
1984 ◽  
Vol 37 (2) ◽  
pp. 137-139 ◽  
Author(s):  
Yasuhiko Tomino ◽  
Masahiko Miura ◽  
Takao Suga ◽  
Masayuki Endoh ◽  
Yasuo Nomoto ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Immune Complexes ◽  
Peripheral Blood ◽  
Polymorphonuclear Leukocytes ◽  
Double Immunofluorescence
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