scholarly journals Impact of aortocaval shunt flow on cardiac and renal function in unilateral nephrectomized rats

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jie Wu ◽  
Zhong Cheng ◽  
Mingjing Zhang ◽  
Pengfei Zhu ◽  
Ye Gu
Keyword(s):  
Renal Function ◽  
Shunt Flow ◽  
Aortocaval Shunt

scholarly journals Renal Function in High-Output Heart Failure in Rats

1999 ◽  
Vol 10 (3) ◽  
pp. 572-580
Author(s):  
ROLAND WILLENBROCK ◽  
INES PAGEL ◽  
MICHAELA SCHEUERMANN ◽  
KLAUS HÖHNEL ◽  
HARALD S. MACKENZIE ◽  
...  
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Systemic Hemodynamic ◽  
Aortocaval Shunt ◽  
Experimental Heart Failure ◽  
Volume Load ◽  
High Output Heart Failure ◽  
Specific Antagonist ◽  
Renal Responses ◽  
High Output

Abstract. The physiologic and pathophysiologic importance of natriuretic peptides (NP) has been imperfectly defined. The diminished renal responses to exogenous atrial NP in heart failure have led to the perception that the endogenous NP system might be less effective and thus contribute to renal sodium retention in heart failure. This study tests the hypothesis that in experimental heart failure, the renal responses to an acute volume load are still dependent on the NP system. The specific antagonist HS-142-1 was used to block the effects of NP in a model of high-output heart failure induced by an aortocaval shunt. Plasma cGMP levels and renal cGMP excretion were significantly lower in shunted and sham-operated rats receiving HS-142-1, compared with vehicle-treated controls, indicating effective blockade of guanylate cyclase-coupled receptors. Baseline sodium excretion and urine flow rate were lower in HS-142-1-treated sham-operated rats (15.2 ± 1.1 μl/min versus 27.5 ± 3.1 μl/min with vehicle, P < 0.001) and in HS-142-1-treated shunted rats (8.1 ± 1.3 μl/min versus 19.9 ± 2.3 μl/min with vehicle, P < 0.001). After an acute volume load, the diuretic and natriuretic responses were attenuated by HS-142-1 in control and shunted rats. The renal responses were reduced by HS-142-1 to a significantly greater extent in shunted rats than in control rats. HS-142-1 did not induce any significant systemic hemodynamic changes in either group, nor did it alter renal blood flow. However, the GFR in HS-142-1-treated shunted rats was lower than that in vehicle-treated shunted rats, both at baseline (0.6 ± 0.3 ml/min versus 2.1 ± 0.4 ml/min with vehicle, P < 0.05) and after an acute volume load (1.2 ± 0.4 ml/min versus 2.6 ± 0.4 ml/min with vehicle, P = 0.01), whereas no such effect was observed in control rats. These data indicate that the maintenance of basal renal function and the responses to acute volume loading are dependent on the NP system. The NP seem to be of particular importance for the maintenance of GFR in this model of experimental heart failure. These observations provide new insights into the importance of the renal NP system in heart failure.

1248: Impact of Surgical Treatment of Renal Carcinoma on Renal Function and Blood Pressure: A Race- and Age-Dependent Association

2007 ◽  
Vol 177 (4S) ◽  
pp. 411-412
Author(s):  
Javier Miller ◽  
Angela Smith ◽  
Kris Gunn ◽  
Erik Kouba ◽  
Eric M. Wallen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Function ◽  
Surgical Treatment ◽  
Renal Carcinoma ◽  
Age Dependent

1636: Unilateral PCNL Alters Bilateral Renal Function

2007 ◽  
Vol 177 (4S) ◽  
pp. 542-543
Author(s):  
Rajash K. Handa ◽  
Lynn R. Willis ◽  
Andrew P. Evan ◽  
Bret A. Connors ◽  
Ryan F. Paterson ◽  
...  
Keyword(s):  
Renal Function

1786: Prediction of Differential Renal Function as Determined by Contrasted and non-contrasted Computerized Tomography

2007 ◽  
Vol 177 (4S) ◽  
pp. 593-594
Author(s):  
Shelby N. Morrisroe ◽  
Erin P. Gibbons ◽  
Benjamin R. Stockton ◽  
Kyongtae T. Bae ◽  
Cheng Hong ◽  
...  
Keyword(s):  
Renal Function ◽  
Computerized Tomography ◽  
Differential Renal Function

875: The Effect of Warm Ischemic Time on the Ipsilateral Renal Function after Laparoscopic Partial Nephrectomy

2006 ◽  
Vol 175 (4S) ◽  
pp. 282-283
Author(s):  
Shigeta Masanobu ◽  
Koji Mita ◽  
Tsuguru Usui ◽  
Kazushi Marukawa ◽  
Toshihiro Tachikake
Keyword(s):  
Renal Function ◽  
Partial Nephrectomy ◽  
Laparoscopic Partial Nephrectomy ◽  
Ischemic Time ◽  
Warm Ischemic Time

754: Artifactual Elevation of Differential Renal Function Measured by Nuclear Scintigraphy in Large Hydronephrotic Kidneys

2006 ◽  
Vol 175 (4S) ◽  
pp. 245-245
Author(s):  
Joao L. Pippi Salle ◽  
Anthony J. Cook ◽  
Frank Papanicolaou ◽  
Darius J. Bagli ◽  
Farhat Walid ◽  
...  
Keyword(s):  
Renal Function ◽  
Nuclear Scintigraphy ◽  
Differential Renal Function

1905: The Effect of Percutaneous Nephrolithotripsy (PCNL) on Renal Function: Assessment with Quantitative Spect of TC 99M-DMSA (QDMSA) Renal Scintigraphy

2004 ◽  
Vol 171 (4S) ◽  
pp. 503-503
Author(s):  
Boaz Moskovitz ◽  
Vladimir Sopov ◽  
Sarel Halachmi ◽  
Michael Mullerad ◽  
Yusef Barbara ◽  
...  
Keyword(s):  
Renal Function ◽  
Renal Scintigraphy ◽  
Quantitative Spect ◽  
Percutaneous Nephrolithotripsy ◽  
Function Assessment

High-Dose Statin Aids Renal Function in CHD

2006 ◽  
Vol 39 (12) ◽  
pp. 43
Author(s):  
BRUCE JANCIN
Keyword(s):  
Renal Function ◽  
High Dose

Abstract #701: A Retrospective Analysis of The Impact of Weight Loss on Renal Function

2016 ◽  
Vol 22 ◽  
pp. 145-146
Author(s):  
Tiffany Schwasinger-Schmidt ◽  
Georges Elhomsy ◽  
Fanglong Dong ◽  
Bobbie Paull-Forney
Keyword(s):  
Weight Loss ◽  
Renal Function ◽  
Retrospective Analysis ◽  
The Impact
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