scholarly journals Respiratory Syncytial Virus whole-genome sequencing identifies convergent evolution of sequence duplication in the C-terminus of the G gene

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Seth A. Schobel ◽  
Karla M. Stucker ◽  
Martin L. Moore ◽  
Larry J. Anderson ◽  
Emma K. Larkin ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Convergent Evolution ◽  
Whole Genome ◽  
C Terminus ◽  
Syncytial Virus

scholarly journals Whole Genome Sequencing and Evolutionary Analysis of Human Respiratory Syncytial Virus A and B from Milwaukee, WI 1998-2010

PLoS ONE ◽  
2011 ◽  
Vol 6 (10) ◽  
pp. e25468 ◽  
Author(s):  
Cecilia Rebuffo-Scheer ◽  
Michael Bose ◽  
Jie He ◽  
Shamim Khaja ◽  
Michael Ulatowski ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Human Respiratory Syncytial Virus ◽  
Whole Genome ◽  
Evolutionary Analysis ◽  
Syncytial Virus

scholarly journals Investigation of Respiratory Syncytial Virus Outbreak on an Adult Stem Cell Transplant Unit by Use of Whole-Genome Sequencing

2017 ◽  
Vol 55 (10) ◽  
pp. 2956-2963 ◽  
Author(s):  
Yijun Zhu ◽  
Teresa R. Zembower ◽  
Kristen E. Metzger ◽  
Zhengdeng Lei ◽  
Stefan J. Green ◽  
...  
Keyword(s):  
Stem Cell ◽  
Respiratory Syncytial Virus ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Stem Cell Transplant ◽  
Pcr Amplification ◽  
Adult Stem Cell ◽  
Cell Transplant ◽  
Whole Genome ◽  
Syncytial Virus

ABSTRACTA viral whole-genome sequencing (WGS) strategy, based on PCR amplification followed by next-generation sequencing, was used to investigate a nosocomial respiratory syncytial virus-B (RSV-B) outbreak in a hematology-oncology and stem cell transplant unit. RSV-B genomes from 16 patients and health care workers (HCWs) suspected to be involved in the outbreak were compared to RSV-B genomes that were acquired from outpatients during the same time period but epidemiologically unrelated to the outbreak. Phylogenetic analysis of the whole genome identified a cluster of 11 patients and HCWs who had an identical RSV-B strain which was clearly distinct from strains recovered from individuals unrelated to the outbreak. Sequence variation of the glycoprotein (G) gene alone was insufficient to distinguish the outbreak strains from the outbreak-unrelated strains, thereby demonstrating that WGS is valuable for local outbreak investigation.

Utility of Whole Genome Sequencing in diagnosing complex disorders: lesson from renal tubular disorders

2018 ◽  
Author(s):  
Mark Stevenson ◽  
Alistair T Pagnamenta ◽  
Heather G Mack ◽  
Judith A Savige ◽  
Kate E Lines ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Whole Genome ◽  
Complex Disorders ◽  
Tubular Disorders ◽  
Renal Tubular Disorders ◽  
Renal Tubular

0306 Exploring the feasibility of using copy number variants as genetic markers through large-scale whole genome sequencing experiments

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 146-146
Author(s):  
D. M. Bickhart ◽  
L. Xu ◽  
J. L. Hutchison ◽  
J. B. Cole ◽  
D. J. Null ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genetic Markers ◽  
Genome Sequencing ◽  
Copy Number ◽  
Large Scale ◽  
Copy Number Variants ◽  
Whole Genome

Evaluation of Whole Genome Sequencing for outbreak detection of Salmonella enterica serovar Enteritidis

2020 ◽  
Author(s):  
Ainhoa Arrieta-Gisasola ◽  
Aitor Atxaerandio Landa ◽  
Javier Garaizar ◽  
Joseba Bikandi ◽  
José Karkamo ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Salmonella Enterica ◽  
Outbreak Detection ◽  
Whole Genome ◽  
Salmonella Enterica Serovar Enteritidis
Sign in / Sign up

Export Citation Format

Share Document