scholarly journals Independent Association between Sleep Fragmentation and Dyslipidemia in Patients with Obstructive Sleep Apnea

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yingjun Qian ◽  
Hongliang Yi ◽  
Jianyin Zou ◽  
Lili Meng ◽  
Xulan Tang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Fragmentation ◽  
Obstructive Sleep ◽  
Independent Association

scholarly journals The Importance of Sleep Fragmentation on the Hemodynamic Dipping in Obstructive Sleep Apnea Patients

2020 ◽  
Vol 11 ◽  
Author(s):  
Richard Staats ◽  
Inês Barros ◽  
Dina Fernandes ◽  
Dina Grencho ◽  
Cátia Reis ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Fragmentation ◽  
Obstructive Sleep

scholarly journals Differential associations of hypoxia, sleep fragmentation, and depressive symptoms with cognitive dysfunction in obstructive sleep apnea

SLEEP ◽  
2020 ◽  
Author(s):  
Ridwan M Alomri ◽  
Gerard A Kennedy ◽  
Siraj Omar Wali ◽  
Faris Ahejaili ◽  
Stephen R Robinson
Keyword(s):  
Obstructive Sleep Apnea ◽  
Depressive Symptoms ◽  
Sleep Apnea ◽  
Sustained Attention ◽  
Sleep Fragmentation ◽  
Sleep Disruption ◽  
Visuospatial Ability ◽  
Treatment Interventions ◽  
Visuospatial Deficits ◽  
Obstructive Sleep

Abstract Obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial or complete cessation of breathing during sleep and increased effort to breathe. This study examined patients who underwent overnight polysomnographic studies in a major sleep laboratory in Saudi Arabia. The study aimed to determine the extent to which intermittent hypoxia, sleep disruption, and depressive symptoms are independently associated with cognitive impairments in OSA. In the sample of 90 participants, 14 had no OSA, 30 mild OSA, 23 moderate OSA, and 23 severe OSA. The findings revealed that hypoxia and sleep fragmentation are independently associated with impairments of sustained attention and reaction time (RT). Sleep fragmentation, but not hypoxia, was independently associated with impairments in visuospatial deficits. Depressive symptoms were independently associated with impairments in the domains of sustained attention, RT, visuospatial ability, and semantic and episodic autobiographical memories. Since the depressive symptoms are independent of hypoxia and sleep fragmentation, effective reversal of cognitive impairment in OSA may require treatment interventions that target each of these factors.

Independent association of vitamin D and insulin resistance in obstructive sleep apnea

2019 ◽  
Vol 80 (5-6) ◽  
pp. 319-323 ◽  
Author(s):  
Zeqin Fan ◽  
Bing Cao ◽  
Hong Long ◽  
Lijie Feng ◽  
Qianjun Li ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep ◽  
Independent Association

Independent association between obstructive sleep apnea severity and liver stiffness

2018 ◽  
Author(s):  
Wojciech Trzepizur ◽  
Jérôme Boursier ◽  
Marc Le Vaillant ◽  
Pierre-Henri Ducluzeau ◽  
Séverine Dubois ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Liver Stiffness ◽  
Obstructive Sleep Apnea Severity ◽  
Obstructive Sleep ◽  
Independent Association

scholarly journals Independent Association Between Obstructive Sleep Apnea Severity and Glycated Hemoglobin in Adults Without Diabetes

Diabetes Care ◽  
2012 ◽  
Vol 35 (9) ◽  
pp. 1902-1906 ◽  
Author(s):  
P. Priou ◽  
M. Le Vaillant ◽  
N. Meslier ◽  
S. Chollet ◽  
P. Masson ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Glycated Hemoglobin ◽  
Obstructive Sleep Apnea Severity ◽  
Obstructive Sleep ◽  
Independent Association

scholarly journals The Association between Obstructive Sleep Apnea and Post Traumatic Stress Disorder

2021 ◽  
pp. 1-4
Author(s):  
Hani Raoul Khouzam ◽  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Stress Disorder ◽  
Sleep Fragmentation ◽  
Post Traumatic Stress ◽  
Accurate Identification ◽  
Sleep Related Breathing Disorders ◽  
Treatment Interventions ◽  
Appropriate Treatment ◽  
Obstructive Sleep

Obstructive sleep apnea (OSA)is a type of sleep-related breathing disorders which is associated with frequent awakenings leading to sleep fragmentation. Posttraumatic stress disorder (PTSD) is a psychiatric disorder that is also associated with sleep fragmentation and disruption. A possible link between OSA and PTSD needs to be accurately identified in patients who present with either OSA or PTSD. This article will review the diagnostic criteria of OSA and PTSD, the proposed link between these two distinct clinical entities and the treatment interventions for both disorders. The accurate identification and appropriate treatment of OSA and PTSD would ultimately prevent sleep disruption and its serious medical and mental complications, leading to improved functioning in patients whose lives are adversely impacted by these disabling medical and mental disorders.

scholarly journals 0613 The Effects of Diabetes on Obstructive Sleep Apnea Severity and Progression: A Propensity Score Analysis

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A234-A235
Author(s):  
Q Li ◽  
B T Keenan ◽  
N M Punjabi ◽  
G Maislin ◽  
S T Kuna
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Propensity Score ◽  
Propensity Score Analysis ◽  
Hdl Cholesterol ◽  
Health Study ◽  
Obstructive Sleep Apnea Severity ◽  
Score Analysis ◽  
Obstructive Sleep ◽  
Independent Association

Abstract Introduction Obstructive sleep apnea (OSA) is associated with increased glucose intolerance and insulin resistance, and commonly coexists with type 2 diabetes mellitus (T2DM). Research suggests an independent association between these two conditions. However, more research into the role of T2DM in the development of OSA, or vice versa, is needed. Methods Leveraging data from 139 participants with T2DM from the Sleep AHEAD cohort and 5,085 participants without T2DM from the Sleep Heart Health Study (SHHS), we conducted two complementary propensity score (PS) subclassification analyses to estimate the effect of T2DM on the oxygen desaturation index (ODI), both at baseline and over 4-5 years of follow-up. PS models included age, sex, race, body mass index, neck circumference, waist circumference, total cholesterol, HDL cholesterol, triglycerides, Epworth Sleepiness Scale, and comorbid hypertension or cardiovascular disease. Models evaluating ODI progression also included baseline ODI. Results The PS subclassification analysis identified 109 participants with T2DM and 480 without T2DM, balanced with respect to baseline covariates, for evaluation of the effect of T2DM on baseline ODI. On average, those with T2DM had a 9 events/hour greater ODI compared to those without (24.3 [20.8, 27.9] vs. 15.3 [13.6, 16.9] events/hour; p<0.0001). Among patients with baseline ODI≥5, a second PS subclassification identified 99 with T2DM and 227 without for evaluating the effect of T2DM on ODI progression. No difference in change in ODI was observed between those with and without T2DM (mean [95% CI] difference -0.25 [-10.7, 10.2] events/hour; p=0.963). Conclusion Using two robust PS subclassification designs to minimize selection bias, we evaluated the effect of T2DM on baseline ODI and ODI progression in adults with OSA after 4-5 years. Those with T2DM had more severe baseline ODI, but there were no meaningful differences in ODI progression. Results further our understanding of the association between these coexisting conditions. Support NIH grant HL070301

scholarly journals Sleep Fragmentation in Obstructive Sleep Apnea

SLEEP ◽  
1996 ◽  
Vol 19 (suppl_9) ◽  
pp. S61-S66 ◽  
Author(s):  
R. John Kimoff
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Fragmentation ◽  
Obstructive Sleep
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