scholarly journals Efficacy and safety of low-molecular-weight heparin in patients with sepsis: a meta-analysis of randomized controlled trials

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yu Fan ◽  
Menglin Jiang ◽  
Dandan Gong ◽  
Chen Zou
Keyword(s):  
Molecular Weight ◽  
Randomized Controlled Trials ◽  
Low Molecular Weight Heparin ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Low Molecular Weight ◽  
Efficacy And Safety ◽  
Randomized Controlled

scholarly journals Meta-analysis of Different Pressing Time on the Incidence of Subcutaneous Hemorrhage of Low Molecular Weight Heparin Administration

2021 ◽  
Vol 27 ◽  
pp. 107602962110386
Author(s):  
Juan Fang ◽  
Gefeng Pan ◽  
Xufei Bao ◽  
Yanhong Wang
Keyword(s):  
Molecular Weight ◽  
Randomized Controlled Trials ◽  
Low Molecular Weight Heparin ◽  
Meta Analysis ◽  
Biomedical Literature ◽  
Controlled Trials ◽  
Low Molecular Weight ◽  
Bleeding Rate ◽  
Randomized Controlled ◽  
Pressing Time

To investigate the effect of different pressing time on the incidence of subcutaneous hemorrhage of low molecular weight heparin (LMWH) administration by meta-analysis. Cochrane Library, PubMed, MEDLINE, CINAHL, EMbase, Springer, EBSCO, China Biomedical Literature Database, CNKI, Wanfang Database, and VIP Database were searched. To screen the literature of randomized controlled trials with different pressing time in patients with subcutaneous LMWH injection from the establishment of the database to December 2020. The quality of the literature was evaluated and the data were extracted. Meta-analysis was performed by RevMan 5.3. A total of 17 randomized controlled trials were included. Meta-analysis showed that the bleeding rate of pressing for 5 min odds ratio (OR  =  3.89, 95% confidence interval [CI]: 2.68-5.64, P < .05) or pressing for 10 min (OR  =  1.99, 95% CI: 1.34-2.95) was significantly lower than that of pressing for 3 min. Moreover, the bleeding rate was significantly lower in the 5 min pressing (OR  =  1.47, 95% CI: 1.18-1.82) and 10 min pressing(OR  =  2.12, 95% CI: 1.61-2.77) than in the no compression group. It is the most suitable time to press 5 min after subcutaneous LMWH injection, which can better control the incidence of bleeding.

Sign in / Sign up

Export Citation Format

Share Document