scholarly journals A life course approach to explore the biological embedding of socioeconomic position and social mobility through circulating inflammatory markers

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Raphaële Castagné ◽  
Cyrille Delpierre ◽  
Michelle Kelly-Irving ◽  
Gianluca Campanella ◽  
Florence Guida ◽  
...  
Author(s):  
José Aparecido Soares Lopes ◽  
Luana Giatti ◽  
Rosane Harter Griep ◽  
Antonio Alberto da Silva Lopes ◽  
Sheila Maria Alvim Matos ◽  
...  

Abstract Background Life course epidemiology is a powerful framework to unravel the role of socioeconomic position (SEP) disparities in hypertension (HTN). This study investigated whether life course SEP is associated with HTN incidence. Specifically, to test whether cumulative low SEP throughout life and unfavorable intergenerational social mobility increased HTN incidence. METHODS Longitudinal analysis of 8,754 ELSA-Brasil participants without HTN or cardiovascular in visit 1 (2008–2010). The response variable was the incidence of HTN between visits 1 and 2 (2012–2014). The explanatory variables were childhood, youth, and adulthood SEP, cumulative low SEP, and intergenerational social mobility. Associations were estimated by incidence rate ratios (IRRs) obtained by generalized linear models, with Poisson distribution and logarithmic link function, after adjustment for sociodemographic, behavioral, and health factors. RESULTS The incidence of HTN was 43.2/1,000 person-years, being higher in males, elderly (70–74 years), self-declared black, and low SEP individuals. After considering sociodemographic factors, low SEP in childhood, youth, and adulthood remained statistically associated with increased HTN incidence. Individuals in the third (IRR: 1.26; 95% confidence interval (CI): 1.11–1.44) and fourth top quartiles (IRR: 1.29; 95% CI: 1.11–1.49) of cumulative low SEP, vs. first, as well as those with low stable intergenerational trajectory (IRR: 1.29; 95% CI: 1.16–1.43), vs. high stable, also had increased HTN incidence rates. Conclusions Socioeconomic disparities at all phases of the life cycle appear to raise HTN incidence rates, being the individuals with greater accumulation of exposure to low SEP and with more unfavorable intergenerational mobility at greatest risk, even in a short follow-up time.


2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Raphaele Castagné ◽  
Michelle Kelly-Irving ◽  
Paolo Vineis ◽  
Marc Chadeau ◽  
Cyrille Delpierre*

2018 ◽  
Vol 107 ◽  
pp. 29-35 ◽  
Author(s):  
Gregore I. Mielke ◽  
Wendy J. Brown ◽  
Ulf Ekelund ◽  
Soren Brage ◽  
Helen Gonçalves ◽  
...  

2010 ◽  
Vol 71 (1) ◽  
pp. 187-195 ◽  
Author(s):  
Eric B. Loucks ◽  
Louise Pilote ◽  
John W. Lynch ◽  
Hugues Richard ◽  
Nisha D. Almeida ◽  
...  

2010 ◽  
Vol 65 (11) ◽  
pp. 964-971 ◽  
Author(s):  
A. Otero-Rodriguez ◽  
L. M. Leon-Munoz ◽  
J. R. Banegas ◽  
P. Guallar-Castillon ◽  
F. Rodriguez-Artalejo ◽  
...  

2021 ◽  
pp. 053901842110221
Author(s):  
Magda Nico

Social mobility is one of the concepts which is the most intrinsically bound to sociology. Hence, the diachronic analysis of this concept contributes to our understanding of sociology and the way that the discipline has changed, as it turned to individual social trajectories according to different topics. Aimed at contributing to this understanding, I’ve developed a literature review based on a systematic collection of the scientific publications in social sciences directly addressing social mobility. A database with conceptual and methodological variables was compiled (N=1054) and worked on. Distinct periods in the life course of this concept have been identified, with the emergence of a scattered concept (1920–1959), the golden age of social mobility (1960–1989), followed by a period of fragmentation and resistance (1990–2012). These three periods are characterized by different methodological and geographical hegemonies, flows and volumes of publications, and also by different tendencies and theoretical and disciplinary rivalries.


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