Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4+ T cell responses through TLR4 ligation

Jolanda Brummelman; René H. M. Raeven; Kina Helm; Jeroen L. A. Pennings; Bernard Metz; Willem van Eden; Cécile A. C. M. van Els; Wanda G. H. Han

doi:10.1038/srep25064

Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4+ T cell responses through TLR4 ligation

Scientific Reports ◽

10.1038/srep25064 ◽

2016 ◽

Vol 6 (1) ◽

Cited By ~ 9

Author(s):

Jolanda Brummelman ◽

René H. M. Raeven ◽

Kina Helm ◽

Jeroen L. A. Pennings ◽

Bernard Metz ◽

...

Keyword(s):

T Cell ◽

Pertussis Vaccine ◽

T Cell Responses ◽

Acellular Pertussis Vaccine ◽

Cd4 T Cell ◽

Cell Responses ◽

Transcriptome Signature

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Bordetella pertussis Fimbriae proteins Fim2 and 3 are Immunodominant in T cell responses to Acellular Pertussis Vaccine (LB509)

The FASEB Journal ◽

10.1096/fasebj.28.1_supplement.lb509 ◽

2014 ◽

Vol 28 (S1) ◽

Author(s):

Myles Dillon ◽

Ravi Kolla ◽

John Sidney ◽

Alessandro Sette

Keyword(s):

T Cell ◽

Pertussis Vaccine ◽

Bordetella Pertussis ◽

T Cell Responses ◽

Acellular Pertussis Vaccine ◽

Cell Responses

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Author response for "Naturally processed HLA‐DR3‐restricted HHV‐6b peptides are recognized broadly with polyfunctional and cytotoxic CD4 T cell responses"

10.1002/eji.201948126/v2/response1 ◽

2019 ◽

Author(s):

Aniuska Becerra‐Artiles ◽

John Cruz ◽

John D. Leszyk ◽

John Sidney ◽

Alessandro Sette ◽

...

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd4 T Cell ◽

Author Response ◽

Cell Responses ◽

Hla Dr3

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Maintenance of virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154

Zeitschrift für Gastroenterologie ◽

10.1055/s-0029-1225685 ◽

2009 ◽

Vol 47 (06) ◽

Author(s):

N Semmo ◽

M Mueller ◽

HC Spangenberg ◽

N Kersting ◽

T Altay ◽

...

Keyword(s):

T Cell ◽

T Cell Responses ◽

Hcv Infection ◽

Cd4 T Cell ◽

Cell Responses ◽

Chronic Hcv Infection ◽

Chronic Hcv

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Characterization and functional modulation of HBV-specific CD4+ T cell responses

Zeitschrift für Gastroenterologie ◽

10.1055/s-0035-1568100 ◽

2015 ◽

Vol 53 (12) ◽

Author(s):

F Jacobi ◽

T Flecken ◽

R Thimme ◽

T Boettler

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd4 T Cell ◽

Cell Responses ◽

Functional Modulation

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Gut microbiota induce local and systemic CD4 T cell responses in healthy individuals that are altered in inflammatory bowel diseases

10.1055/s-0037-1604874 ◽

2017 ◽

Author(s):

AN Hegazy ◽

N West ◽

MJT Stubbington ◽

E Wendt ◽

K Suijker ◽

...

Keyword(s):

T Cell ◽

Gut Microbiota ◽

Inflammatory Bowel Diseases ◽

T Cell Responses ◽

Cd4 T Cell ◽

Healthy Individuals ◽

Cell Responses ◽

Bowel Diseases ◽

Inflammatory Bowel

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Faculty Opinions recommendation of In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1005730.68761 ◽

2002 ◽

Author(s):

Christopher A Hunter

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd4 T Cell ◽

Intracellular Pathogens ◽

Cell Responses

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Faculty Opinions recommendation of Central memory CD4+ T cell responses in chronic HIV infection are not restored by antiretroviral therapy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020334.233434 ◽

2004 ◽

Author(s):

Luis J Montaner

Keyword(s):

T Cell ◽

Antiretroviral Therapy ◽

Hiv Infection ◽

T Cell Responses ◽

Central Memory ◽

Cd4 T Cell ◽

Cell Responses ◽

Chronic Hiv Infection

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Faculty Opinions recommendation of CD40-CD40 ligand interaction between dendritic cells and CD8+ T cells is needed to stimulate maximal T cell responses in the absence of CD4+ T cell help.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1071829.524753 ◽

2007 ◽

Author(s):

Marcia Blackman

Keyword(s):

T Cells ◽

Dendritic Cells ◽

T Cell ◽

Cd8 T Cells ◽

T Cell Responses ◽

Cd40 Ligand ◽

Cd4 T Cell ◽

Ligand Interaction ◽

Cell Responses ◽

T Cell Help

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Faculty Opinions recommendation of Cutting edge: Conditional MHC class II expression reveals a limited role for B cell antigen presentation in primary and secondary CD4 T cell responses.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718020496.793480946 ◽

2013 ◽

Author(s):

Tim Manser

Keyword(s):

T Cell ◽

B Cell ◽

Antigen Presentation ◽

Mhc Class Ii ◽

T Cell Responses ◽

Class Ii ◽

Cutting Edge ◽

Cd4 T Cell ◽

Cell Antigen ◽

Cell Responses

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Faculty Opinions recommendation of Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718219822.793492887 ◽

2014 ◽

Author(s):

Harold Nelson

Keyword(s):

T Cell ◽

Specific Immunotherapy ◽

T Cell Responses ◽

Cd4 T Cell ◽

Dependent Manner ◽

Cell Responses

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